Home Neuronal Signaling Adrenergic Receptor antagonist Propranolol

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Propranolol Adrenergic Receptor antagonist

Cat.No.E5827

Propranolol is a non-selective antagonist of β-adrenergic receptors (βAR), with Ki values of 1.8 nM for β1AR and 0.8 nM for β2AR, effectively lowering cAMP levels and activating the MAPK pathway downstream of βARs. It is an effective treatment for infantile hemangiomas (IHs), where it induces antiproliferative and antisurvival effects on hemangioma stem cells (HemSCs).
Propranolol Adrenergic Receptor antagonist Chemical Structure

Chemical Structure

Molecular Weight: 259.34

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Quality Control

Batch: E582701 DMSO]52 mg/mL]false]Ethanol]13 mg/mL]false]Water]Insoluble]false Purity: 94.86%
94.86

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Chemical Information, Storage & Stability

Molecular Weight 259.34 Formula

C16H21NO2

 Storage (From the date of receipt)
CAS No. 525-66-6 Download SDF Storage of Stock Solutions

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Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-06-17)

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