Epinephrine HCl

Catalog No.S3061 Synonyms: Adrenaline

For research use only.

Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.

Epinephrine HCl Chemical Structure

CAS No. 55-31-2

Selleck's Epinephrine HCl has been cited by 1 Publication

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Biological Activity

Description Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.
Targets
Adrenergic Receptor [1]
In vitro

Epinephrine has many functions in the body, regulating heart rate, blood vessel and air passage diameters, and metabolic shifts. Epinephrine release is a crucial component of the fight-or-flight response of the sympathetic nervous system.In chemical terms, epinephrine is one of a group of monoamines called the catecholamines. It is produced in some neurons of the central nervous system, and in the chromaffin cells of the adrenal medulla from the amino acids phenylalanine and tyrosine.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 44 mg/mL
(200.3 mM)
Water 44 mg/mL
(200.3 mM)
Ethanol 7 mg/mL
(31.86 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 219.67
Formula

C9H13NO3.HCl

CAS No. 55-31-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CNCC(C1=CC(=C(C=C1)O)O)O.Cl

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04801810 Recruiting Other: Normobaric hypoxia|Other: Normobaric normoxia Overweight and Obesity Florida State University May 2022 Not Applicable
NCT05179499 Not yet recruiting Drug: Norepinephrine|Other: Balanced Crystalloid Sepsis NHS Greater Glasgow and Clyde|University of Glasgow|University of Edinburgh|Salford Royal NHS Foundation Trust|Imperial College London|Guy''s and St Thomas'' NHS Foundation Trust|St George''s University of London March 1 2022 Phase 3
NCT04316611 Not yet recruiting Drug: Potassium chloride Out-of-hospital Cardiac Arrest (OHCA) Assistance Publique - Hôpitaux de Paris|URC-CIC Paris Descartes Necker Cochin February 2022 Phase 2

(data from https://clinicaltrials.gov, updated on 2022-01-17)

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