For research use only.
Catalog No.S3061 Synonyms: Adrenaline
Molecular Weight(MW): 219.67
Epinephrine HCl is a hormone and a neurotransmitter.
Purity & Quality Control
Choose Selective Adrenergic Receptor Inhibitors
|Description||Epinephrine HCl is a hormone and a neurotransmitter.|
Epinephrine has many functions in the body, regulating heart rate, blood vessel and air passage diameters, and metabolic shifts. Epinephrine release is a crucial component of the fight-or-flight response of the sympathetic nervous system.In chemical terms, epinephrine is one of a group of monoamines called the catecholamines. It is produced in some neurons of the central nervous system, and in the chromaffin cells of the adrenal medulla from the amino acids phenylalanine and tyrosine.
|In vitro||DMSO||44 mg/mL (200.3 mM)|
|Water||44 mg/mL (200.3 mM)|
|Ethanol||7 mg/mL (31.86 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT04123067||Suspended||Drug: Pioglitazone 45 mg|Drug: Placebo oral tablet||Stroke Acute|Hyperglycemia|Diabetes||Milton S. Hershey Medical Center|National Center for Advancing Translational Science (NCATS)||July 1 2020||Phase 1|Phase 2|
|NCT04325321||Not yet recruiting||Other: Stress reactivity test||Takotsubo Cardiomyopathy||The Miriam Hospital|National Heart Lung and Blood Institute (NHLBI)||June 1 2020||Not Applicable|
|NCT04130984||Recruiting||Device: EZ-IO||Out-of-Hospital Cardiac Arrest||Second Affiliated Hospital School of Medicine Zhejiang University|The First Affiliated Hospital of Soochow University|The Sixth Affiliated Hospital of Wenzhou Medical University|The Affiliated Hospital of Xuzhou Medical University|Second Affiliated Hospital of Wenzhou Medical University|Shanghai 10th People''s Hospital|The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School|The First Affiliated Hospital with Nanjing Medical University|West China Hospital|Shanghai Zhongshan Hospital|Ningbo Medical Center Lihuili Hospital|Henan Provincial People''s Hospital|The First Affiliated Hospital of Zhengzhou University|Shandong Provincial Hospital|The Third Affiliated Hospital of Wenzhou Medical University|Sir Run Run Shaw Hospital||June 2020||Not Applicable|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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