- Inhibitory Selectivity
|Catalog No.||Product Name||Solubility(25°C)|
|S5704||Myclobutanil||-1 mg/mL||58 mg/mL||-1 mg/mL|
|S9341||3,4-Dimethoxycinnamic acid||-1 mg/mL||42 mg/mL||-1 mg/mL|
|S5499||Amantadine||-1 mg/mL||1 mg/mL||-1 mg/mL|
|S5268||Solithromycin||<1 mg/mL||100 mg/mL||25 mg/mL|
|S5025||Efinaconazole||<1 mg/mL||69 mg/mL||69 mg/mL|
|S4854||Bedaquiline fumarate||<1 mg/mL||100 mg/mL||4 mg/mL|
|S2348||Rotenone (Barbasco)||<1 mg/mL||55 mg/mL||2 mg/mL|
|S2597||Oseltamivir Phosphate||<1 mg/mL||4 mg/mL||<1 mg/mL|
|S2527||Methacycline HCl||5 mg/mL||3 mg/mL||<1 mg/mL|
|S1677||Chloramphenicol||<1 mg/mL||65 mg/mL||65 mg/mL|
|S2716||Peramivir Trihydrate||<1 mg/mL||0.2 mg/mL||<1 mg/mL|
|S1606||Clotrimazole||<1 mg/mL||11 mg/mL||69 mg/mL|
|S1956||Miconazole Nitrate||<1 mg/mL||96 mg/mL||1 mg/mL|
|S2557||Terbinafine HCl||<1 mg/mL||66 mg/mL||66 mg/mL|
|S2457||Clindamycin HCl||92 mg/mL||92 mg/mL||<1 mg/mL|
|S1611||Cefoperazone||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S3007||Zanamivir||25 mg/mL||2 mg/mL||<1 mg/mL|
|S2908||Hygromycin B||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S1854||Bifonazole||<1 mg/mL||62 mg/mL||20 mg/mL|
|S1876||Valaciclovir HCl||72 mg/mL||14 mg/mL||<1 mg/mL|
|S1997||Liranaftate||<1 mg/mL||<1 mg/mL||<1 mg/mL|
|S4042||Nafcillin Sodium||91 mg/mL||91 mg/mL||20 mg/mL|
|S1791||Bacitracin Zinc||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S2572||Streptomycin sulfate||89 mg/mL||<1 mg/mL||<1 mg/mL|
|S1685||Sulfanilamide||<1 mg/mL||34 mg/mL||17 mg/mL|
|S8279||Shikonin||<1 mg/mL||57 mg/mL||23 mg/mL|
|S7550||Erythromycin Cyclocarbonate||<1 mg/mL||100 mg/mL||100 mg/mL|
|S7784||Fumagillin||<1 mg/mL||92 mg/mL||32 mg/mL|
|S3077||Tazobactam||<1 mg/mL||60 mg/mL||<1 mg/mL|
|S4647||Cefmenoxime hydrochloride||<1 mg/mL||70 mg/mL||<1 mg/mL|
|S4602||Acetohydroxamic acid||15 mg/mL||15 mg/mL||15 mg/mL|
|S4198||Aminothiazole||20 mg/mL||20 mg/mL||20 mg/mL|
|S3710||Fosfomycin calcium||<1 mg/mL||0.1 mg/mL||<1 mg/mL|
|S3667||Imipenem||63 mg/mL||1 mg/mL||<1 mg/mL|
|S4105||Closantel Sodium||<1 mg/mL||100 mg/mL||100 mg/mL|
|S4106||Closantel||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S3732||Avibactam sodium||57 mg/mL||57 mg/mL||<1 mg/mL|
|S3028||Geneticin (G418 Sulfate)||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S7417||Puromycin 2HCl||100 mg/mL||100 mg/mL||<1 mg/mL|
|S4286||Anidulafungin (LY303366)||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S1958||Sulbactam||47 mg/mL||47 mg/mL||47 mg/mL|
|S4564||Diethylcarbamazine citrate||78 mg/mL||78 mg/mL||30 mg/mL|
|S4986||Latamoxef sodium||100 mg/mL||100 mg/mL||<1 mg/mL|
|S1373||Daptomycin||100 mg/mL||100 mg/mL||<1 mg/mL|
|S1408||Linezolid||<1 mg/mL||67 mg/mL||8 mg/mL|
|S1097||BTZ043 Racemate||<1 mg/mL||22 mg/mL||<1 mg/mL|
|S1517||Natamycin||<1 mg/mL||7 mg/mL||<1 mg/mL|
|S1403||Tigecycline||100 mg/mL||100 mg/mL||<1 mg/mL|
|S5491||Lomefloxacin||-1 mg/mL||7 mg/mL||-1 mg/mL|
|S5700||Phthalylsulfathiazole||-1 mg/mL||80 mg/mL||-1 mg/mL|
|S5397||Chlorhexidine||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5637||Cefotiam Hexetil Hydrochloride||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5724||Dichlorophene||-1 mg/mL||54 mg/mL||-1 mg/mL|
|S9046||Berberine||1 mg/mL||45 mg/mL||5 mg/mL|
|S9328||5,6,7-Trimethoxyflavone||-1 mg/mL||10 mg/mL||-1 mg/mL|
|S9342||1,4-Naphthoquinone||-1 mg/mL||32 mg/mL||-1 mg/mL|
|S5684||Lapachol||-1 mg/mL||48 mg/mL||-1 mg/mL|
|S5638||Cefozopran hydrochloride||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5644||Ceftriaxone Sodium||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5601||Balofloxacin Dihydrate||<1 mg/mL||2 mg/mL||2 mg/mL|
|S3623||Ceftibuten dihydrate||-1 mg/mL||90 mg/mL||-1 mg/mL|
|S5533||Tobramycin sulfate||100 mg/mL||<1 mg/mL||-1 mg/mL|
|S5531||Doripenem||-1 mg/mL||60 mg/mL||-1 mg/mL|
|S5532||Erythromycin estolate||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5535||Moxifloxacin||-1 mg/mL||24 mg/mL||-1 mg/mL|
|S5054||Rifamycin sodium salt||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5207||Cephalexin Monohydrate||<1 mg/mL||0.01 mg/mL||<1 mg/mL|
|S5487||Cefoperazone sodium||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5546||Sulfacetamide||-1 mg/mL||43 mg/mL||-1 mg/mL|
|S5328||Gamithromycin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S5719||Ceftizoxime sodium||81 mg/mL||81 mg/mL||<1 mg/mL|
|S5065||Ganciclovir sodium||55 mg/mL||55 mg/mL||<1 mg/mL|
|S5475||Novaluron||-1 mg/mL||99 mg/mL||-1 mg/mL|
|S5406||Sultamicillin Tosylate||9 mg/mL||100 mg/mL||100 mg/mL|
|S5278||Tedizolid (TR-700)||-1 mg/mL||10 mg/mL||-1 mg/mL|
|S5657||Ertapenem sodium||100 mg/mL||100 mg/mL||<1 mg/mL|
|S5353||Cefpiramide sodium||100 mg/mL||100 mg/mL||<1 mg/mL|
|S5352||Cefminox Sodium||100 mg/mL||100 mg/mL||<1 mg/mL|
|S5356||Ceftiofur||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5411||Sultamicillin||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S3966||Nifuratel||<1 mg/mL||57 mg/mL||<1 mg/mL|
|S5373||Pseudolaric Acid B||<1 mg/mL||86 mg/mL||86 mg/mL|
|S5354||Cefteram pivoxil||<1 mg/mL||0.01 mg/mL||<1 mg/mL|
|S5351||Cefmetazole sodium||98 mg/mL||98 mg/mL||1 mg/mL|
|S5247||Selamectin||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5560||Midecamycin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S5573||Tilmicosin phosphate||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5350||Cefpodoxime proxetil||<1 mg/mL||100 mg/mL||100 mg/mL|
|S3971||Fusidine||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5541||Dimetridazole||-1 mg/mL||28 mg/mL||-1 mg/mL|
|S5473||Pivmecillinam hydrochloride||95 mg/mL||95 mg/mL||95 mg/mL|
|S5359||Butoconazole||-1 mg/mL||82 mg/mL||-1 mg/mL|
|S5366||Fipronil||-1 mg/mL||87 mg/mL||-1 mg/mL|
|S5213||Piroctone Olamine||<1 mg/mL||38 mg/mL||59 mg/mL|
|S4850||Flucloxacillin sodium||95 mg/mL||95 mg/mL||5 mg/mL|
|S4846||Meropenem Trihydrate||87 mg/mL||87 mg/mL||4 mg/mL|
|S4865||Cefetamet pivoxil hydrochloride||<1 mg/mL||100 mg/mL||100 mg/mL|
|S4833||Cefoxitin sodium||89 mg/mL||89 mg/mL||<1 mg/mL|
|S5355||Piperaquine phosphate||2 mg/mL||<1 mg/mL||-1 mg/mL|
|S5456||Isobavachalcone||<1 mg/mL||64 mg/mL||64 mg/mL|
|S4996||Tavaborole (AN-2690)||<1 mg/mL||30 mg/mL||30 mg/mL|
|S5440||Berberine Sulfate||-1 mg/mL||20 mg/mL||-1 mg/mL|
|S5557||Aklomide||-1 mg/mL||40 mg/mL||-1 mg/mL|
|S5331||Ceftezole sodium||92 mg/mL||92 mg/mL||<1 mg/mL|
|S5333||Sulbenicillin Sodium||91 mg/mL||91 mg/mL||<1 mg/mL|
|S5420||Clindamycin alcoholate||-1 mg/mL||95 mg/mL||-1 mg/mL|
|S5421||Fluoroquinolonic Acid||-1 mg/mL||25 mg/mL||-1 mg/mL|
|S5296||Cephradine monohydrate||4 mg/mL||<1 mg/mL||-1 mg/mL|
|S5290||Ormetoprim||<1 mg/mL||0.01 mg/mL||<1 mg/mL|
|S5294||Cephalotin acid||-1 mg/mL||79 mg/mL||-1 mg/mL|
|S5291||sulfaisodimidine||-1 mg/mL||55 mg/mL||-1 mg/mL|
|S5298||Amoxicillin trihydrate||-1 mg/mL||30 mg/mL||-1 mg/mL|
|S5289||Ceftezole||-1 mg/mL||88 mg/mL||-1 mg/mL|
|S5299||Tosufloxacin p-Toluenesulfonate Hydrate||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5295||Lincomycin Hydrochloride Monohydrate||-1 mg/mL||92 mg/mL||-1 mg/mL|
|S5292||Diazolidinyl urea||-1 mg/mL||55 mg/mL||-1 mg/mL|
|S5492||Econazole||-1 mg/mL||76 mg/mL||-1 mg/mL|
|S5515||Penicillin G Procaine||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5332||Cefquinome sulfate||9 mg/mL||100 mg/mL||<1 mg/mL|
|S5227||Erythromycin thiocyanate||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S4880||Cefathiamidine||-1 mg/mL||94 mg/mL||-1 mg/mL|
|S4999||Avermectin B1||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5048||Fosfomycin Disodium||36 mg/mL||<1 mg/mL||-1 mg/mL|
|S5051||Pipemidic acid||60 mg/mL||<1 mg/mL||-1 mg/mL|
|S5081||Ceforanide||-1 mg/mL||6 mg/mL||-1 mg/mL|
|S5035||6-Aminopenicillanic acid||<1 mg/mL||1 mg/mL||<1 mg/mL|
|S5092||Febantel||-1 mg/mL||89 mg/mL||-1 mg/mL|
|S4878||Neticonazole Hydrochloride||-1 mg/mL||67 mg/mL||-1 mg/mL|
|S5093||Rafoxanide||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5095||Olaquindox||<1 mg/mL||0.01 mg/mL||<1 mg/mL|
|S5214||Imidocarb dipropionate||-1 mg/mL||39 mg/mL||-1 mg/mL|
|S5055||Milbemycin Oxime||<1 mg/mL||100 mg/mL||100 mg/mL|
|S5070||Mupirocin calcium||6 mg/mL||100 mg/mL||100 mg/mL|
|S5096||SulfadiMethoxine sodium||-1 mg/mL||66 mg/mL||-1 mg/mL|
|S5099||4-Aminophenylarsonic acid||-1 mg/mL||43 mg/mL||-1 mg/mL|
|S5209||Enoxacin Sesquihydrate||-1 mg/mL||4 mg/mL||-1 mg/mL|
|S5212||Imidazolidinyl Urea||-1 mg/mL||77 mg/mL||-1 mg/mL|
|S5211||4-Aminosalicylic acid||-1 mg/mL||10 mg/mL||-1 mg/mL|
|S4971||Buparvaquone||<1 mg/mL||65 mg/mL||4 mg/mL|
|S4978||Azathramycin||<1 mg/mL||50 mg/mL||100 mg/mL|
|S5033||Terconazole||<1 mg/mL||49 mg/mL||100 mg/mL|
|S4866||Nicarbazin||<1 mg/mL||9 mg/mL||<1 mg/mL|
|S5016||Isoprinosine||100 mg/mL||100 mg/mL||2 mg/mL|
|S5041||Difloxacin hydrochloride||98 mg/mL||98 mg/mL||98 mg/mL|
|S2501||Pyrantel Pamoate||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S4942||4-Hydroxy-3,5-dimethoxybenzyl alcohol||-1 mg/mL||36 mg/mL||-1 mg/mL|
|S4874||Cefazedone||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S4822||Silver Sulfadiazine||<1 mg/mL||0.1 mg/mL||<1 mg/mL|
|S4959||Skatole||-1 mg/mL||26 mg/mL||-1 mg/mL|
|S5020||Tilorone dihydrochloride||96 mg/mL||43 mg/mL||96 mg/mL|
|S4898||Sulfalozine sodium||-1 mg/mL||56 mg/mL||-1 mg/mL|
|S4882||Resorantel||-1 mg/mL||61 mg/mL||-1 mg/mL|
|S5017||Oxyclozanide||-1 mg/mL||80 mg/mL||-1 mg/mL|
|S4870||Cefodizime Sodium||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S4847||Faropenem Sodium||61 mg/mL||12 mg/mL||<1 mg/mL|
|S4875||Cephapirin Benzathine||-1 mg/mL||81 mg/mL||-1 mg/mL|
|S4885||Taurolidine||-1 mg/mL||56 mg/mL||-1 mg/mL|
|S4876||Robenidine Hydrochoride||-1 mg/mL||74 mg/mL||-1 mg/mL|
|S4869||Sulfamethoxazole sodium||-1 mg/mL||55 mg/mL||-1 mg/mL|
|S4848||Dalbavancin||100 mg/mL||100 mg/mL||<1 mg/mL|
|S5012||Octenidine Dihydrochloride||-1 mg/mL||60 mg/mL||-1 mg/mL|
|S3999||α-santonin||-1 mg/mL||49 mg/mL||-1 mg/mL|
|S5007||Delamanid||<1 mg/mL||100 mg/mL||2 mg/mL|
|S4812||Ceftizoxime||<1 mg/mL||76 mg/mL||<1 mg/mL|
|S3978||5-Phenyl-2,4-pentadienoic acid||-1 mg/mL||6 mg/mL||-1 mg/mL|
|S5159||Doxycycline||-1 mg/mL||88 mg/mL||-1 mg/mL|
|S4813||Cefuroxime axetil||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S4843||Potassium acetate||-1 mg/mL||6 mg/mL||-1 mg/mL|
|S4844||Cefcapene Pivoxil Hydrochloride||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S5009||Brivudine||-1 mg/mL||66 mg/mL||-1 mg/mL|
|S5005||Cefotiam hydrochloride||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S3910||4',7-Dimethoxyisoflavone||-1 mg/mL||4 mg/mL||-1 mg/mL|
|S5108||Tylosin||-1 mg/mL||100 mg/mL||-1 mg/mL|
|S3801||Sodium Houttuyfonate||<1 mg/mL||2 mg/mL||<1 mg/mL|
|S3979||Zinc Undecylenate||-1 mg/mL||36 mg/mL||-1 mg/mL|
|S3787||Picroside I||-1 mg/mL||98 mg/mL||-1 mg/mL|
|S3941||Pinocembrin||<1 mg/mL||51 mg/mL||51 mg/mL|
|S4759||p-Coumaric Acid||<1 mg/mL||32 mg/mL||32 mg/mL|
|S3741||Benznidazole||<1 mg/mL||52 mg/mL||5 mg/mL|
|S1878||Ganciclovir||<1 mg/mL||27 mg/mL||<1 mg/mL|
|S2504||Ribavirin||49 mg/mL||49 mg/mL||<1 mg/mL|
|S1807||Aciclovir||<1 mg/mL||45 mg/mL||<1 mg/mL|
|S1374||Doripenem Hydrate||26 mg/mL||36 mg/mL||<1 mg/mL|
|S1381||Meropenem||8 mg/mL||76 mg/mL||<1 mg/mL|
|S1162||PA-824||<1 mg/mL||72 mg/mL||16 mg/mL|
|S1934||Nystatin (Fungicidin)||<1 mg/mL||19 mg/mL||<1 mg/mL|
|S1741||Rifabutin||<1 mg/mL||60 mg/mL||40 mg/mL|
|S1370||Biapenem||16 mg/mL||<1 mg/mL||<1 mg/mL|
|S1351||Ivermectin||<1 mg/mL||100 mg/mL||28 mg/mL|
|S1371||Cefoselis Sulfate||5 mg/mL||3 mg/mL||<1 mg/mL|
|S2159||Tebipenem Pivoxil||<1 mg/mL||99 mg/mL||87 mg/mL|
|S1636||Amphotericin B||<1 mg/mL||22 mg/mL||<1 mg/mL|
|S1282||Artemisinin||<1 mg/mL||57 mg/mL||24 mg/mL|
|S1399||Teicoplanin||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S2468||Fenbendazole||<1 mg/mL||4 mg/mL||<1 mg/mL|
|S1505||Aztreonam||11 mg/mL||87 mg/mL||<1 mg/mL|
|S1725||Terbinafine||<1 mg/mL||58 mg/mL||58 mg/mL|
|S2510||Spectinomycin 2HCl||81 mg/mL||81 mg/mL||<1 mg/mL|
|S1768||Cefditoren Pivoxil||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S1450||Nanchangmycin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S1839||Chloroxine||<1 mg/mL||43 mg/mL||<1 mg/mL|
|S2264||Artemether||<1 mg/mL||60 mg/mL||60 mg/mL|
|S1666||Flucytosine||5 mg/mL||8 mg/mL||<1 mg/mL|
|S1998||D-Cycloserine||20 mg/mL||<1 mg/mL||<1 mg/mL|
|S2479||Lincomycin HCl||89 mg/mL||89 mg/mL||<1 mg/mL|
|S1605||Cefdinir||<1 mg/mL||79 mg/mL||<1 mg/mL|
|S3073||Caspofungin Acetate||100 mg/mL||-1 mg/mL||-1 mg/mL|
|S2528||Ciclopirox||<1 mg/mL||42 mg/mL||42 mg/mL|
|S2152||Sitafloxacin Hydrate||<1 mg/mL||4 mg/mL||<1 mg/mL|
|S1502||Cephalexin||10 mg/mL||2 mg/mL||<1 mg/mL|
|S1835||Azithromycin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S1773||Oxytetracycline (Terramycin)||<1 mg/mL||92 mg/mL||10 mg/mL|
|S1637||Docosanol||<1 mg/mL||<1 mg/mL||4 mg/mL|
|S2535||Econazole nitrate||<1 mg/mL||89 mg/mL||5 mg/mL|
|S2568||Neomycin sulfate||143 mg/mL||<1 mg/mL||<1 mg/mL|
|S1777||Ethionamide||<1 mg/mL||33 mg/mL||17 mg/mL|
|S1635||Erythromycin||3 mg/mL||147 mg/mL||147 mg/mL|
|S2420||Aloperine||12 mg/mL||2 mg/mL||46 mg/mL|
|S4226||Minocycline HCl||1 mg/mL||<1 mg/mL||<1 mg/mL|
|S2486||Moroxydine HCl||42 mg/mL||42 mg/mL||<1 mg/mL|
|S1644||Nitrofural||<1 mg/mL||40 mg/mL||<1 mg/mL|
|S3079||Atovaquone||<1 mg/mL||5 mg/mL||<1 mg/mL|
|S4050||Valganciclovir HCl||78 mg/mL||78 mg/mL||<1 mg/mL|
|S4052||Netilmicin Sulfate||288 mg/mL||<1 mg/mL||<1 mg/mL|
|S4082||Spiramycin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S2565||Amoxicillin Sodium||78 mg/mL||78 mg/mL||<1 mg/mL|
|S2544||Cefprozil hydrate||<1 mg/mL||<1 mg/mL||<1 mg/mL|
|S2563||Oxacillin sodium monohydrate||88 mg/mL||<1 mg/mL||<1 mg/mL|
|S3129||Trimethoprim||<1 mg/mL||58 mg/mL||<1 mg/mL|
|S2028||Diclazuril||<1 mg/mL||16 mg/mL||<1 mg/mL|
|S3161||Sertaconazole nitrate||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S1499||Cefaclor||<1 mg/mL||11 mg/mL||<1 mg/mL|
|S1915||Sulfamethoxazole||<1 mg/mL||51 mg/mL||23 mg/mL|
|S2120||Arbidol HCl||<1 mg/mL||103 mg/mL||22 mg/mL|
|S2467||Famciclovir||64 mg/mL||64 mg/mL||48 mg/mL|
|S2031||Fenticonazole Nitrate||<1 mg/mL||104 mg/mL||2 mg/mL|
|S2574||Tetracycline HCl||96 mg/mL||96 mg/mL||<1 mg/mL|
|S2575||Vancomycin HCl||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S1851||Oxibendazole||<1 mg/mL||1 mg/mL||<1 mg/mL|
|S4030||Gentamicin Sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S2514||Tobramycin||94 mg/mL||<1 mg/mL||<1 mg/mL|
|S1762||Pyrazinamide||12 mg/mL||25 mg/mL||2 mg/mL|
|S1676||Amorolfine HCl||9 mg/mL||28 mg/mL||71 mg/mL|
|S4075||Zinc Pyrithione||<1 mg/mL||30 mg/mL||<1 mg/mL|
|S2530||7-Aminocephalosporanic acid||<1 mg/mL||1 mg/mL||<1 mg/mL|
|S2536||Miconazole||<1 mg/mL||83 mg/mL||83 mg/mL|
|S2543||Ceftiofur HCl||<1 mg/mL||100 mg/mL||22 mg/mL|
|S1691||Praziquantel||<1 mg/mL||63 mg/mL||63 mg/mL|
|S4237||Primaquine Diphosphate||91 mg/mL||91 mg/mL||<1 mg/mL|
|S1964||Rimantadine||33 mg/mL||33 mg/mL||33 mg/mL|
|S1883||Idoxuridine||<1 mg/mL||35 mg/mL||<1 mg/mL|
|S3162||Tylosin tartrate||200 mg/mL||300 mg/mL||300 mg/mL|
|S1916||Sulfisoxazole||<1 mg/mL||53 mg/mL||2 mg/mL|
|S1770||Sulfadiazine||<1 mg/mL||50 mg/mL||<1 mg/mL|
|S3195||Azlocillin sodium salt||97 mg/mL||97 mg/mL||3 mg/mL|
|S4004||Ethambutol 2HCl||56 mg/mL||56 mg/mL||<1 mg/mL|
|S2469||Fleroxacin||<1 mg/mL||<1 mg/mL||<1 mg/mL|
|S2551||Sulbactam sodium||51 mg/mL||3 mg/mL||<1 mg/mL|
|S3116||Sulfathiazole||<1 mg/mL||51 mg/mL||<1 mg/mL|
|S1910||Tioconazole||<1 mg/mL||78 mg/mL||78 mg/mL|
|S2506||Roxithromycin||<1 mg/mL||167 mg/mL||167 mg/mL|
|S2048||Clindamycin Phosphate||101 mg/mL||<1 mg/mL||<1 mg/mL|
|S3055||Besifloxacin HCl||1 mg/mL||<1 mg/mL||<1 mg/mL|
|S4120||Sulconazole Nitrate||<1 mg/mL||92 mg/mL||<1 mg/mL|
|S2511||Sulfadoxine||<1 mg/mL||62 mg/mL||<1 mg/mL|
|S3067||Chlorhexidine 2HCl||<1 mg/mL||100 mg/mL||<1 mg/mL|
|S3059||Enrofloxacin||<1 mg/mL||3 mg/mL||<1 mg/mL|
|S4141||Dinitolmide||<1 mg/mL||45 mg/mL||1 mg/mL|
|S1977||Sarafloxacin HCl||<1 mg/mL||4 mg/mL||<1 mg/mL|
|S4146||Bacitracin||100 mg/mL||-1 mg/mL||-1 mg/mL|
|S4147||Azithromycin Dihydrate||10 mg/mL||100 mg/mL||100 mg/mL|
|S4044||Toltrazuril||<1 mg/mL||85 mg/mL||<1 mg/mL|
|S4254||Apramycin Sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S4056||Retapamulin||<1 mg/mL||104 mg/mL||104 mg/mL|
|S3015||Amoxicillin||<1 mg/mL||73 mg/mL||<1 mg/mL|
|S4184||Penciclovir||1 mg/mL||34 mg/mL||<1 mg/mL|
|S4191||Betamipron||<1 mg/mL||39 mg/mL||39 mg/mL|
|S1957||Sulfamethizole||<1 mg/mL||54 mg/mL||10 mg/mL|
|S2537||Secnidazole||37 mg/mL||37 mg/mL||37 mg/mL|
|S4195||Broxyquinoline||<1 mg/mL||17 mg/mL||<1 mg/mL|
|S4196||Ethacridine lactate monohydrate||5 mg/mL||72 mg/mL||<1 mg/mL|
|S4093||Bismuth Subcitrate Potassium||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S4094||Tetramisole HCl||41 mg/mL||<1 mg/mL||<1 mg/mL|
|S2539||Lomefloxacin HCl||6 mg/mL||1 mg/mL||<1 mg/mL|
|S2612||Ribitol||30 mg/mL||30 mg/mL||<1 mg/mL|
|S3122||Amikacin hydrate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S3105||Nadifloxacin||<1 mg/mL||20 mg/mL||<1 mg/mL|
|S4234||Capreomycin Sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S3133||Sulfamethazine||<1 mg/mL||56 mg/mL||<1 mg/mL|
|S1855||Pefloxacin Mesylate||67 mg/mL||14 mg/mL||<1 mg/mL|
|S3154||Butenafine HCl||<1 mg/mL||70 mg/mL||70 mg/mL|
|S3156||Naftifine HCl||<1 mg/mL||<1 mg/mL||8 mg/mL|
|S1833||Butoconazole nitrate||<1 mg/mL||95 mg/mL||<1 mg/mL|
|S3179||Carbenicillin disodium||84 mg/mL||5 mg/mL||<1 mg/mL|
|S3193||Ticarcillin sodium||86 mg/mL||86 mg/mL||<1 mg/mL|
|S1881||Protionamide||<1 mg/mL||36 mg/mL||7 mg/mL|
|S1830||Oxfendazole||<1 mg/mL||10 mg/mL||<1 mg/mL|
|S4726||Lauric Acid||20 mg/mL||40 mg/mL||40 mg/mL|
|S3621||Pazufloxacin mesylate||82 mg/mL||82 mg/mL||7 mg/mL|
|S4576||Sulfabenzamide||<1 mg/mL||55 mg/mL||<1 mg/mL|
|S4579||Resorcinol||22 mg/mL||22 mg/mL||22 mg/mL|
|S2583||Thiamphenicol||<1 mg/mL||71 mg/mL||<1 mg/mL|
|S4594||Cephalothin||83 mg/mL||10 mg/mL||<1 mg/mL|
|S4420||Mefloquine HCl||<1 mg/mL||82 mg/mL||82 mg/mL|
|S1617||Sulfapyridine||<1 mg/mL||2 mg/mL||<1 mg/mL|
|S4029||Colistin Sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S4122||Tilmicosin||8 mg/mL||100 mg/mL||<1 mg/mL|
|S2052||Oxytetracycline Dihydrate||<1 mg/mL||5 mg/mL||<1 mg/mL|
|S2058||Tolnaftate||<1 mg/mL||62 mg/mL||<1 mg/mL|
|S4584||Butylparaben||38 mg/mL||38 mg/mL||38 mg/mL|
|S4585||Succinylsulfathiazole||<1 mg/mL||71 mg/mL||<1 mg/mL|
|S4142||Clopidol||<1 mg/mL||1 mg/mL||<1 mg/mL|
|S4592||Captisol (SBE-β-CD)||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S4595||Cefazolin Sodium||95 mg/mL||95 mg/mL||<1 mg/mL|
|S4145||Decoquinate||<1 mg/mL||0.01 mg/mL||<1 mg/mL|
|S4596||Cefixime||<1 mg/mL||90 mg/mL||1 mg/mL|
|S4148||Ampicillin Trihydrate||2 mg/mL||81 mg/mL||<1 mg/mL|
|S2259||Aloe-emodin||<1 mg/mL||3 mg/mL||<1 mg/mL|
|S4041||Olsalazine Sodium||41 mg/mL||4 mg/mL||<1 mg/mL|
|S4150||Orbifloxacin||<1 mg/mL||0.05 mg/mL||<1 mg/mL|
|S4620||Cefuroxime sodium||89 mg/mL||89 mg/mL||<1 mg/mL|
|S4250||Sulfamethoxypyridazine||<1 mg/mL||56 mg/mL||<1 mg/mL|
|S4156||Chlortetracycline HCl||1 mg/mL||5 mg/mL||<1 mg/mL|
|S4158||Ceftriaxone Sodium Trihydrate||100 mg/mL||1 mg/mL||<1 mg/mL|
|S4160||Penicillin G Sodium||71 mg/mL||71 mg/mL||<1 mg/mL|
|S2271||Berberine chloride||<1 mg/mL||40 mg/mL||<1 mg/mL|
|S2282||Cinchonidine||<1 mg/mL||59 mg/mL||59 mg/mL|
|S4610||Mebendazole||<1 mg/mL||6 mg/mL||<1 mg/mL|
|S4167||Cyromazine||1 mg/mL||33 mg/mL||2 mg/mL|
|S4612||Dapson||<1 mg/mL||49 mg/mL||10 mg/mL|
|S1884||Sparfloxacin||<1 mg/mL||9 mg/mL||<1 mg/mL|
|S1395||Polymyxin B sulphate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S2385||Hordenine||<1 mg/mL||33 mg/mL||33 mg/mL|
|S4634||Sodium sulfadiazine||54 mg/mL||9 mg/mL||<1 mg/mL|
|S4172||Cetylpyridinium Chloride||68 mg/mL||68 mg/mL||68 mg/mL|
|S4641||Tedizolid Phosphate||<1 mg/mL||22 mg/mL||<1 mg/mL|
|S3695||Cystamine dihydrochloride||45 mg/mL||14 mg/mL||2 mg/mL|
|S4175||Sulfaguanidine||<1 mg/mL||43 mg/mL||<1 mg/mL|
|S2395||Rheochrysidin||<1 mg/mL||1 mg/mL||<1 mg/mL|
|S3645||Kitasamycin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S4178||Climbazole||<1 mg/mL||59 mg/mL||59 mg/mL|
|S3644||Sulfamonomethoxine||<1 mg/mL||56 mg/mL||4 mg/mL|
|S3646||Thimerosal||80 mg/mL||80 mg/mL||20 mg/mL|
|S4179||Mezlocillin Sodium||100 mg/mL||100 mg/mL||<1 mg/mL|
|S4060||Erythromycin Ethylsuccinate||<1 mg/mL||172 mg/mL||172 mg/mL|
|S3649||Ceftazidime||100 mg/mL||4 mg/mL||<1 mg/mL|
|S4062||Ronidazole||<1 mg/mL||40 mg/mL||<1 mg/mL|
|S4183||Paromomycin Sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S3655||Cefepime Dihydrochloride Monohydrate||1 mg/mL||100 mg/mL||<1 mg/mL|
|S4541||Triclosan||<1 mg/mL||57 mg/mL||57 mg/mL|
|S4187||Salicylanilide||<1 mg/mL||43 mg/mL||18 mg/mL|
|S4068||Tinidazole||<1 mg/mL||49 mg/mL||<1 mg/mL|
|S3676||Carbendazim||<1 mg/mL||17 mg/mL||<1 mg/mL|
|S2315||Kanamycin sulfate||52 mg/mL||<1 mg/mL||<1 mg/mL|
|S4192||Chlorquinaldol||<1 mg/mL||46 mg/mL||6 mg/mL|
|S4258||Luliconazole||<1 mg/mL||71 mg/mL||5 mg/mL|
|S4750||Sulfacetamide sodium salt hydrate||50 mg/mL||50 mg/mL||2 mg/mL|
|S4081||Sulfacetamide Sodium||51 mg/mL||19 mg/mL||<1 mg/mL|
|S3636||Cefadroxil hydrate||1 mg/mL||7 mg/mL||<1 mg/mL|
|S3637||Cefpirome sulfate||100 mg/mL||100 mg/mL||<1 mg/mL|
|S3638||Cefamandole nafate||100 mg/mL||100 mg/mL||<1 mg/mL|
|S2534||Isoconazole nitrate||<1 mg/mL||41 mg/mL||4 mg/mL|
|S3713||Moxidectin||<1 mg/mL||100 mg/mL||100 mg/mL|
|S7411||Ascomycin (FK520)||<1 mg/mL||100 mg/mL||100 mg/mL|
|S3705||Chlorobutanol||<1 mg/mL||35 mg/mL||35 mg/mL|
|S3707||Ethopabate||<1 mg/mL||47 mg/mL||47 mg/mL|
|S3708||Sulfachloropyridazine||<1 mg/mL||56 mg/mL||9 mg/mL|
|S4201||Florfenicol||<1 mg/mL||72 mg/mL||8 mg/mL|
|S4663||Fusidate Sodium||100 mg/mL||100 mg/mL||100 mg/mL|
|S3709||Furagin||<1 mg/mL||52 mg/mL||<1 mg/mL|
|S4203||Furaltadone HCl||72 mg/mL||17 mg/mL||<1 mg/mL|
|S3058||Danofloxacin Mesylate||91 mg/mL||<1 mg/mL||<1 mg/mL|
|S4271||Isepamicin Sulphate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S3672||Cefonicid sodium||100 mg/mL||100 mg/mL||<1 mg/mL|
|S4213||Dirithromycin||<1 mg/mL||11 mg/mL||100 mg/mL|
|S4215||Ribostamycin Sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S4216||Valnemulin HCl||100 mg/mL||100 mg/mL||100 mg/mL|
|S4671||Cefradine||10 mg/mL||<1 mg/mL||<1 mg/mL|
|S2334||Oleanolic Acid||<1 mg/mL||21 mg/mL||7 mg/mL|
|S4222||Piperacillin Sodium||100 mg/mL||100 mg/mL||100 mg/mL|
|S4601||Clioquinol||<1 mg/mL||61 mg/mL||1 mg/mL|
|S3650||Penicillin V potassium salt||77 mg/mL||<1 mg/mL||<1 mg/mL|
|S2613||Clorsulon||<1 mg/mL||76 mg/mL||7 mg/mL|
|S4111||Dicloxacillin Sodium||100 mg/mL||100 mg/mL||22 mg/mL|
|S3722||Isavuconazole||<1 mg/mL||87 mg/mL||87 mg/mL|
|S2564||Cloxacillin Sodium||55 mg/mL||55 mg/mL||25 mg/mL|
|S3121||Ornidazole||2 mg/mL||44 mg/mL||44 mg/mL|
|S4232||Nithiamide||<1 mg/mL||37 mg/mL||<1 mg/mL|
|S3618||Acetylspiramycin (ASPM)||<1 mg/mL||100 mg/mL||15 mg/mL|
|S4517||Cefotaxime sodium||95 mg/mL||95 mg/mL||<1 mg/mL|
|S4518||Chloroxylenol||<1 mg/mL||31 mg/mL||31 mg/mL|
|S3132||Sulfamerazine||<1 mg/mL||53 mg/mL||<1 mg/mL|
|S4236||Proflavine Hemisulfate||22 mg/mL||<1 mg/mL||<1 mg/mL|
|S3065||Amikacin disulfate||10 mg/mL||<1 mg/mL||<1 mg/mL|
|S4523||Dihydrostreptomycin sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S3746||Lumefantrine||<1 mg/mL||13 mg/mL||<1 mg/mL|
|S4525||Ethylparaben||<1 mg/mL||33 mg/mL||33 mg/mL|
|S4528||Furazolidone||<1 mg/mL||45 mg/mL||<1 mg/mL|
|S4678||Povidone iodine||28 mg/mL||28 mg/mL||28 mg/mL|
|S3139||Methenamine||<1 mg/mL||28 mg/mL||9 mg/mL|
|S4536||Nitrofurantoin||<1 mg/mL||47 mg/mL||<1 mg/mL|
|S3170||Ampicillin sodium||74 mg/mL||37 mg/mL||74 mg/mL|
|S2352||Salinomycin||0.01 mg/mL||0.005 mg/mL||<1 mg/mL|
|S4540||Sisomicin sulfate||100 mg/mL||<1 mg/mL||<1 mg/mL|
|S4242||Cetrimonium Bromide (CTAB)||100 mg/mL||5 mg/mL||100 mg/mL|
|S4279||Demeclocycline HCl||26 mg/mL||100 mg/mL||<1 mg/mL|
|S4550||Azelaic acid||37 mg/mL||37 mg/mL||37 mg/mL|
|S4287||Micafungin Sodium||100 mg/mL||-1 mg/mL||-1 mg/mL|
|S4553||Bronopol||39 mg/mL||39 mg/mL||39 mg/mL|
|S1962||Sulphadimethoxine||<1 mg/mL||62 mg/mL||<1 mg/mL|
|S4555||Carsalam||<1 mg/mL||32 mg/mL||2 mg/mL|
|S4559||Cloxiquine||<1 mg/mL||35 mg/mL||35 mg/mL|
|S7896||Sodium Tauroursodeoxycholate (TUDC)||100 mg/mL||100 mg/mL||71 mg/mL|
|S4522||Dehydroacetic acid||<1 mg/mL||33 mg/mL||33 mg/mL|
|S4565||Diiodohydroxyquinoline||<1 mg/mL||13 mg/mL||<1 mg/mL|
- Anti-infection Inhibitors (454)
- New Anti-infection Products
|Catalog No.||Information||Product Use Citations||Product Validations|
Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
3,4-Dimethoxycinnamic acid is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.
Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
Trilobatin, a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
Amantadine is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
Solithromycin, belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
Efinaconazole is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
Bedaquiline fumarate, an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.
Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport.
Oseltamivir Phosphate is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.
Nystatin, filipin III, and oseltamivir inhibit the labeling of trophozoites by CTXB and GM1 antibodies. (A) Trophozoites were treated with nystatin (27 μM), filipin III (7.6 μM), and oseltamivir (20 μM) for 30 min before labeling with Alexa Fluor-conjugated CTXB antibody (images a to d) and GM1 antibody (images a′ to d′). Myriocin (27 μM), a sphingolipid inhibitor, was used as a negative control (images e and e′). N, nucleus; PM, plasma membrane; F, flagella; VD, ventral disc. Bars, 5 μm. (B and C) Changes in intensity of control and inhibitor-treated trophozoites. For intensity measurements, cells were randomly selected from 10 to 15 fields from 3 to 5 separate experiments. Approximately 50 cells were considered for each condition and were analyzed using Zeiss Zen 2009 confocal software. One-way ANOVAs were performed to evaluate differences (means ± SDs) between the treatment and control groups. Mean intensities from 3 to 5 separate experiments are shown in panels B and C. Statistical significance was calculated using a one-way ANOVA test, followed by the Tukey (B) and Holm-Šídák (C) methods. *, P < 0.05; **, P < 0.01; ***, P < 0.001; NS, not significant.
Methacycline HCl is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.
Chloramphenicol is a bacteriostatic by inhibiting protein synthesis.
Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of peramivir (C) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
Clotrimazole alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.
Miconazole Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.
Terbinafine HCl inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.
Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.
Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.
Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of oseltamivir zanamivir (B) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.
Bifonazole is a substituted imidazole antifungal agent.
Valaciclovir HCl, an aciclovir prodrug, inhibits activity of virus DNA polymerase, used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus, and for prophylaxis against cytomegalovirus (CMV).
Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.
Nafcillin sodium reversibly inhibits β-lactamase with Kd of 33 mM.
Bacitracin is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.
Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
Tazobactam is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.
Cefmenoxime, a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.
Fosfomycin is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.
Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.
Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
Puromycin 2HCl is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.
Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.
Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
Sulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
Latamoxef sodium is an antibiotic and has anti-bacterial and anti-inflammation effects.
Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
Same experiment as in Figure 2 with fluorescent daptomycin shown as confocal images. A 7/3 DOPC/DOPG GUV (including 1% Rh-PE) was introduced at time zero into a solution containing 1 uM daptomycin with 0.5 uM BODIPY-daptomycin and 1 mM Ca2+. To show colocalization of lipid and peptide in aggregates, confocal images were taken: red for RH-PE and green for BODIPY-daptomycin. As the protrusion length decreased, aggregates appeared on the GUV surface containing both lipid and peptide. The scale bar is 10 um.
Linezolid is a synthetic antibiotic used for the treatment of serious infections.
Auranofin inhibits MRSA toxin production and effectively clears intracellular bacteria. (a) Toxin production (ng/ml) in S. aureus MRSA USA300 after treatment with auranofin or control antibiotics (linezolid or vancomycin) for one hour (data corrected for organism burden). The results are presented as mean ± SD (n = 3). Statistical analysis was done by two-tailed Student’s ‘t’ test. Asterisks (**) indicate statistical significance in relation to the control (DMSO or water). P values of (**P ≤ 0.01) are considered significant. Detailed “P” values are listed below. α-hemolysin: control vs linezolid: 0.0027, control vs auranofin: 0.001. Panton-Valentine leukocidin: control vs linezolid: 0.0017, control vs auranofin: 0.0040. (b) MRSA USA300 infected J774A.1 cells were treated with auranofin and control antibiotics (vancomycin or linezolid) for 24 hours and the percent bacterial reduction was calculated compared to untreated control groups. The results are given as mean ± SD (n = 3). Two-tailed Student’s ‘t’ test was employed and P values of (*,# ≤ 0.05) are deemed significant. Auranofin was compared to controls (*) and to antibiotics (#). Detailed “P” values are listed below. Control vs linezolid: 0.0234, control vs vancomycin: 0.021, control vs auranofin: 0.02031, linezolid vs auranofin: 0.0397, vancomycin vs auranofin: 0.0491.
BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
Natamycin, a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference
Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.
CHX blocked Pim-1 AUG isoform translocation from the cytosol to mitochondria and led to reduced pBADS112. Cox-2 was examined to assess the effect of tigecycline on mitochondrial translation. Cy-Cox-2: cytoplasmic Cox-2; Mt-Cox-2: mitochondrial Cox-2.
Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
Atractylon, the sesquiterpenoid oxide isolated from the rhizomes of Atractylodes japonica and its related plants (Compositae), shows significant antiviral activities for influenza A virus.
Lomefloxacin is a fluoroquinolone antibiotic used to treat bacterial infections.
Phthalylsulfathiazole is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.
Isoeugenol, an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.
Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
Dichlorophen is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
Berberine, an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.
5,6,7-Trimethoxyflavone, methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
1,4-Naphthoquinone, found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide.
Lapachol, a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.
Ammonium lactate is the ammonium salt of lactic acid with mild anti-bacterial properties.
Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.
Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic.
Spiramycin I is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity.
Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.
Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.
Doripenem is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.
Erythromycin, a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.
Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity.
Cefoperazone Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
Sulfacetamide is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Tomatine is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
Maackiain is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.
Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.
Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
Pneumocandin B0 is a natural product and a key intermediate in the synthesis of the antifungal agent.
Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
Steviolbioside, a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.
Gamithromycin is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease.
Scutellarein, extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities
Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants, such as Pueraria thunbergiana Benth, Belamcanda chinensis, and Iris unguicularis. It has been reported to exert pharmacological actions, including antitumor and antibacterial effects, free radical neutralization, and selective estrogen receptor modulation.
Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.
Neochlorogenic acid is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
Rhoifolin, a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
Orientin, isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
Kaempferitrin, isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
Ononin is an isoflavone glycoside with anti-inflammtory effects.
Ceftizoxime sodium is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
Sinigrin is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects. Sinigrin is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
Epigoitrin, the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
Benzathine penicilline is an antibiotic useful for the treatment of a number of bacterial infections.
Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.
Ganciclovir Sodium is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV).
Novaluron belongs to the class of insecticides called insect growth regulators with pesticide properties.
Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
Ertapenem Sodium is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.
Cefpiramide sodium (CPMS) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
Cefminox Sodium is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.
Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
Sultamicillin is a newly developed antibiotic in which ampicillin and the β-lactamase inhibitor sulbactam are linked as an ester.
Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Selamectin is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.
Midecamycin is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.
Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
Fusidine, isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
Butoconazole is an imidazole antifungal used in gynecology.
Fipronil is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.
Piroctone Olamine is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
Flucloxacillin sodium is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.
Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic.
Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
Isobavachalcone, a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
Berberine sulfate, an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
Aklomide is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
Ceftezole Sodium is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
Sulbenicillin Sodium is the sodium salt of sulbenicillin, which is a penicillin antibiotic.
Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
Fluoroquinolonic Acid is an antibiotic and antimicrobial agent.
Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture.
Cephalotin acid is a cephalosporin antibiotic.
Sulfisomidin is a sulfonamide antibacterial.
Amoxicillin is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.
Ceftezole is a semi-synthetic first-generation cephalosporin with antibacterial activity.
Tosufloxacin is a fluoroquinolone antibiotic that is used to treat susceptible infections.
Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
Diazolidinyl urea is an antimicrobial preservative used in cosmetics.
Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.
Procaine benzylpenicillin, also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
Cefquinome sulphate is a veterinary, parenteral, and fourth-generation cephalosporin. Its antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
Fosfomycin is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
Pipemidic acid is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative and some gram-positive bacteria.
Ceforanide is a new cephalosporin with antibacterial activity and has a longer elimination half-life than any currently available cephalosporin.
6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin.
Febantel is a prodrug that is metabolized to fenbendazole and oxfendazole, which are undoubtedly the active parasiticides.
Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
Rafoxanide is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.
Olaquindox is an oral anti-bacterial agent used as an additive to animal food.
Imidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis.
Milbemycin Oxime is a broad spectrum anti-parasitic drug that is active against worms (anthelmintic) and mites (miticide).
Mupirocin Calcium is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.
Sulfadimethoxine is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.
4-Aminophenylarsonic acid (Arsanilic Acid) is an organoarsenic compound with activity as an anti-infective agent.
p-Anisaldehyde (4-methoxybenzaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
Enoxacin sesquihydrate is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
Imidazolidinyl Urea is an antimicrobial agent used as preservative in cosmetics.
Quinocetone is a novel veterinary chemicals that is also bacteriocide and potential anti-tumor agent.
4-Aminosalicylic acid (Aminosalicylic acid) is an antitubercular agent with bacteriostatic activity against Mycobacterium tuberculosis.
Azathramycin (Azaerythromycin) is a macrolide antibiotic containing cladinose.
Terconazole is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.
Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug.
Isoprinosine is an immunopharmacologic agent with antiviral activities.
Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic used in veterinary medicine.
Pyrantel pamoate, a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
4-Hydroxy-3,5-dimethoxybenzyl alcohol, also known as Syringic alcohol, is a kind of phenol with antiviral properties.
Cefazedone is a semisynthetic first-generation cephalosporin with antibacterial activity.
Silver sulfadiazine is a bactericidal for many gram- negative and gram-positive bacteria as well as being effective against yeast.
Skatole (3-Methylindole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.
Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.
Sulfalozine sodium is an antiprotozoal useful in coccidiosis research.
Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp.
Oxyclozanide is a salicylanilide anthelmintic and mitochondrial uncoupling anthelmintic drug approved for veterinary use.
Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases.
Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
Cephapirin Benzathine is the benzathine salt form of cephapirin, which is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.
Taurolidine is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.
Robenidine hydrochloride is an anticoccidial agent mainly for poultry.
Sulfamethoxazole sodium is an antibiotic used for bacterial infections.
Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci.
Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria.
α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
Delamanid is a new anti-tuberculosis drug with an excellent intracellular bactericidal activity and a high accumulation rate.
Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
5-Phenyl-2,4-pentadienoic acid is used as Synthetic building block, anti-malarial agent.
Doxycycline is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa.
Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
Potassium acetate is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.
Cefotiam hydrochloride is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
Tylosin is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
Zinc Undecylenate is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
Picroside I, an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
Allicin, the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
Pinocembrin is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities.
p-Coumaric acid is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.
Benznidazole is a nitroimidazole derivative having an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM in a cell-free assay.
Effect of ganciclovir on viral DNA accumulation (A,B) and induction of TGF-β1 production after human cytomegalovirus infection in human trabecular meshwork cells (C). Cells were harvested at 5 day post-infection at a high multiplicity of infection (MOI 1) under the treatment with different concentrations of ganciclovir (GAN). Treatment with 10 μmol of ganciclovir significantly decreased the viral DNA accumulation (p < 0.001) (A,B). However, treatment with ganciclovir did not affect the TGF-β production using a TGF-β1 luciferase bioassay. Results are expressed as the mean +/− standard deviation of three different experiments.
Ribavirin, a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.
(E) Left panel, Western blot showed that 20 μM Ribavirin effectively inhibits elevated Sox2 expression in irradiated SW1990 cells. Right panel, qPCR analysis showed that Sox2 mRNA level in irradiated SW1990 cells at 48 hours was lower than that in non-irradiated SW1990 cells, *p < 0.05. (F) Left panel, Western blot showed 20 μM Ribavirin inhibits elevated Sox2 expression in irradiated BxPc-3 cells. Right panel, qPCR analysis showed that there is no significant fluctuation of Sox2 mRNA in irradiated BxPc-3 cells and Ribavirin did not influence sox2 mRNA level in irradiated BxPc-3 cells.
Aciclovir is a synthetic nucleoside analogue active against herpesviruses.
(A) HONE1 and (B) HK1-EBV cells were treated with TPA (40 ng/ml) and SB (3 mM) for EBV induction. After 3 h, uninduced and induced HONE1 and HK1-EBV cells were treated with the vehicle control (0.006% DMSO) or indicated concentrations of berberine for 48 h. Subsequently, the culture medium was harvested for quantitative-PCR analysis with EBNA1 primers. Each sample was normalized to the amount of the GAPDH gene; *p<0.05, compared with the control group.
Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.
Meropenem is an ultra-broad spectrum injectable antibiotic.
PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.
Rifabutin is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.
Biapenem is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.
Cefoselis is a widely used beta-lactam antibiotic.
Tebipenem pivoxil is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.
Amphotericin B (AmB) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.
Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.
Teicoplanin is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
Aztreonam is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.
Terbinafine is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
Spectinomycin 2HCl is a new parenteral antibiotic prepared from Streptomyces spectabilis.
Cefditoren Pivoxil is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.
Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.
Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.
Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
Flucytosine (5-Fluorocytosine, 5-FC) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
D-cycloserine is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.
Lincomycin hydrochloride(Lincocin) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
Cefdinir is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.
Caspofungin acetate is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.
Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator.
Sitafloxacin Hydrate is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.
Cephalexin is an antibiotic that can treat a number of bacterial infections.
Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
Oxytetracycline is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.
Effect of FDA approved drugs on EBOV transfected donor and recipient immune cells. (A) Varying concentrations of Cambinol and Esomepraole (1 nM, 1 μM, 10 μM), Oxytetracycline (1 nM, 10 nM, 10 μM), and DMSO (0.00001, 0.0001, 0.001%) treatments were administered to VP40-transfected 293T cells, followed by incubation for 3 days. Supernatant was centrifuged to remove cellular material and subsequently incubated for 72 h at 4°C with 20 μL of 30% slurry of NT80/82 beads. The NT pellet was washed twice with PBS and resuspended in SDS Laemmli buffer, followed by Western blot analysis for levels of exosomal markers CD63 and Alix. Actin levels were also analyzed. Mid-log phase EVTR2C cells (containing VP40) were treated with either low (0.1 μM), medium (1 μM), or high (10 μM) concentrations of Oxytetracycline and incubated for 5 days along with untreated 293T cells. Cell-free supernatants were harvested, filtered, and used to treat CEM (B), Jurkat (C), and U937 (D) cells. Cells were incubated for 5 days and assayed with CellTiter-Glo for viability. Statistical significance was determined using two-tailed student’s t-test with all groups compared to the untreated 293T cell control groups. RLU, Relative Luminescent Units. ∗p < 0.05, ∗∗∗p < 0.001.
Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. (ED50=2.5 mg/mL for plaque inhibition, and ED50=1.7 mg/mL for inhibition of virus production)
Econazole Nitrate is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.
Neomycin sulfate is an aminoglycoside antibiotic, used to treat bacteria infections.
Ethionamide is an antibiotic used in the treatment of tuberculosis.
Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).
Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
Minocycline HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.
Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.
Nitrofural is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)
Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.
Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.
Spiramycin is a 16-membered ring macrolide (antibiotic).
Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
Oxacillin sodium monohydrate is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
Diclazuril is an anti-coccidial drug.
Sertaconazole nitrate is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
Cefaclor is a cephalosporin antibiotic.
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.
Arbidol HCl is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.
Famciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.
Fenticonazole Nitrate is an azole antifungal agent.
Tetracycline HCl is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.
Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.
Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.
Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.
Tobramycin is an aminoglycoside antibiotic with an IC50 of 9.7 μM.
Pyrazinamide is an agent used to treat tuberculosis.
Amorolfine HCl is an antifungal reagent.
Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
Miconazole (Monistat) is an imidazole antifungal agent.
Ceftiofur HCl is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
Praziquantel is an anthelmintic effective against flatworms.
Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.
Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.
Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent.
Sulfadiazine is a sulfonamide antibiotic.
Azlocillin is an acylampicillin with a broad spectrum against bacteria.
Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
Fleroxacin is a new broad-spectrum fluoroquinolone.
Sulbactam sodium (Unasyn) is an irreversible β-lactamase inhibitor.
Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.
Tioconazole is an antifungal medication with an average IC50 of 1.7 μM.
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.
Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.
Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
Sulfadoxine is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.
Enrofloxacin is a fluoroquinolone antibiotic.
Dinitolmide is a broad-spectrum anticoccidial drug.
Sarafloxacin HCl is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L.
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.
Azithromycin Dihydrate is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.
Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
Apramycin is an aminoglycoside antibiotic, which binds to the deep groove of the RNA.
Retapamulin is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM.
Amoxicillin is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.
Penciclovir is a purine acyclic nucleoside analogue with potent antiviral activity.
Betamipron is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.
Sulfamethizole is a sulfathiazole antibacterial agent.
Secnidazole (Flagentyl) is a nitroimidazole anti-infective.
Broxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.
Ethacridine lactate monohydrate is an aromatic organic compound based on acridine used as an antiseptic agent.
Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.
Tetramisole is a mixture of dextro- and levo isomers used as an anthelmintic.
Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.
Ribitol is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections.
Nadifloxacin is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.
Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.
Sulfamethazine is a sulfonamide antibacterial.
Pefloxacin Mesylate is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.
Butenafine HCl is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
Butoconazole nitrate is an anti-fungal agent that inhibits PHA-stimulated release of cytokines-- IL-2, TNFα, IFN and GM-CSF from human peripheral blood lymphocytes (IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively).
Carbenicillin is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
Protionamide is a drug used in the treatment of tuberculosis.
Oxfendazole is a broad spectrum benzimidazole anthelmintic.
Lauric Acid is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Pazufloxacin Mesylate, also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.
m-Tolyl acetate is a pharmaceutical intermediate and antiseptic.
Sulfabenzamide is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.
Resorcinol is a chemical compound that serves as an antiseptic,an disinfectant, and a chemical intermediate for the production of many other pharmaceuticals.
Triacetin is a triglyceride that is used as an antifungal agent.
Thiamphenicol is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.
Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
Sulfapyridine is a sulfonamide antibacterial.
Colistin is a cyclic cationic decapeptide linked to a fatty acid side chain, it belongs to a group of similarly structured bacterial antimicrobial peptides.
Tilmicosin is a macrolide antibiotic.
Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
Butylparaben is a chemical compound commonly used as an antifungal preservative in cosmetic products.
Succinylsulfathiazole, a sulfonamide, is an antibiotic.
Clopidol is an antiprotozoal agent.
Captisol (SBE-β-CD) is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.
Cefazolin Sodium is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Decoquinate is a coccidiostat.
Cefixime is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
Ampicillin Trihydrate is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.
Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.
Flow cytometry result. Promastigotes were stained with Annexin V and propidium iodide 48 hours after treatment with aloe-emodin
Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.
Values represent the average scores for each group ± S.E. (N = 10 per group). The differences between individual experimental groups and 17 days DSS only group were statistically significant (p < 0.05) for all groups.
Orbifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic.
Cefuroxime Sodium is a cephalosporin effective against gram-positive and gram-negative bacteria with resistance to β-lactamase.
Sulfamethoxypyridazine is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.
Chlortetracycline HCl is the first identified tetracycline antibiotic.
Ceftriaxone sodium trihydrate is a third-generation cephalosporin antibiotic.
Penicillin G Sodium is a β-lactam antibiotic produced by Penicillin spp.
Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids.
Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.
Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake.
Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.
Sparfloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
Polymyxin B is an antibiotic primarily used for resistant gram-negative infections.
Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
Sodium Sulfadiazine is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.
Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
Cystamine dihydrochloride acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes.
Sulfaguanidine is a sulfonamide used as an anti-infective agent.
Physcion is an anthraquinone from roots of Rheum officinale Baill.
AmpC β-lactamase and MDH inhibition dose-response curves in the absence (black circles) and presence (red triangles) of DTT for (C and D) physcion.
Kitasamycin is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens.
Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits.
Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
Thimerosal is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks.
Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
Ceftazidime is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.
Ronidazole is an antiprotozoal agent.
Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.
Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.
Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
Salicylanilides are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.
Tinidazole is an anti-parasitic drug.
Carbendazim is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
Kanamycin sulfate(Kanamycin monosulfate) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.
Chlorquinaldol is an antimicrobial agent used for local antisepsy.
Luliconazole is a broad-spectrum antifungal drug.
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.
Sulfacetamide Sodium is an anti-biotic.
Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
Cefpirome is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.
Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Isoconazole nitrate (Travogen) is an azole antifungal reagent.
Moxidectin is a potent, broad-spectrum endectocide with activity against a wide range of nematodes, insects and acari.
Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.
Chlorobutanol (trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
Ethopabate (ETP) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.
Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.
Florfenicol is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
Furagin is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.
Furaltadone HCl is an antibacterial and has distinct curative effect in the treatment of coccidiosis.
Danofloxacin is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM.
Isepamicin Sulphate is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
Cefonicid sodium is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
Dirithromycin is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.
Ribostamycin is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidiﬁcus.
Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
Cephradine is a semi-synthetic cephalosporin antibiotic.
Oleanolic Acid is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.
Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.
Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep.
Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.
Isavuconazole is a new extended-spectrum triazole with activity against yeasts, molds, and dimorphic fungi that inhibits cytochrome P450 (CYP)-dependent 14α-lanosterol demethylation, which is essential for fungal cell membrane ergosterol synthesis.
Cloxacillin Sodium is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.
Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
Nithiamide is a non-5-nitroimidazole drugs.
Acetylspiramycin (ASPM) is a macrolide antimicrobial agent.
Cefotaxime sodium salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.
Sulfamerazine is a sulfonamide antibacterial.
Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.
Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.
Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria.
Ethylparaben is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
Furazolidone is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.
Povidone iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.
Methenamine is an antibiotic used for the treatment of urinary tract infection.
Nitrofurantoin is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.
Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family.
Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug.
Drug sensitivity of KPC tumor cell subpopulations. CD133, Aldefluor, and Sca-1-positive or -negative cells or unsorted KPC cells were cultured in the presence of increasing concentrations of salinomycin. After 72 hours, cell viability was assessed using CellTiter Glo reagent, and percent viability was normalized to vehicle-treated controls. Pair-wise multiple comparisons were performed with one-way ANOVA with Bonferroni adjustment. P values < 0.05 were considered statistically significant.
Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora.
Cetrimonium Bromide is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.
Demeclocycline HCl is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.
8-Hydroxyquinoline is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.
Azelaic acid is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.
Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.
Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
Bronopol(2-bromo-2-nitropropane-1,3-diol) is antibacterial agent, used as preservative in cosmetic industry.
Sulphadimethoxine is a non-reducing glucuronide.
Carsalam is a nonsteroidal anti-inflammatory drug.
Cloxiquine is an antibacterial, antifungal, antiaging and antituberculosis drug.
Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.
DEET is a commen active ingredient insect repellent.
Dehydroacetic acid is an organic compound, used mostly as a fungicide and bactericide.
Diiodohydroxyquinoline is a topical therapeutic agent,a quinoline derivative, with satisfactory antibacterial properties.