Ademetionine disulfate tosylate

Catalog No.S4515

For research use only.

Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.

Ademetionine disulfate tosylate Chemical Structure

CAS No. 97540-22-2

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Biological Activity

Description Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
In vivo Continuous oral administration of ademetionine for 7 days may induce the activities of CYP450 isoforms CYP1A2 of rats, while it may inhibit the activities of CYP2D6, CYP3A4, CYP2C19 and CYP2C9[1].

Protocol (from reference)

Animal Research:[1]
  • Animal Models: Sprague-Dawley rats
  • Dosages: 50 mg/kg
  • Administration: p.o.

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 766.80
Formula

C22H34N6O16S4

CAS No. 97540-22-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C[S+](CCC(N)C([O-])=O)CC1OC(C(O)C1O)[N]2C=NC3=C(N)N=CN=C23.CC4=CC=C(C=C4)[S](O)(=O)=O.O[S](O)(=O)=O.O[S](O)(=O)=O

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