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Chlorquinaldol

Name: Chlorquinaldol
Brand: Selleck Chemicals
SKU: S4192
Rating: 5 (2 reviews)

Synonyms: Chloquinan

Catalog No.S4192 Purity: 99.66%

Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.

Chlorquinaldol Chemical Structure

CAS: 72-80-0

Selleck's Chlorquinaldol has been cited by 2 publications

Purity & Quality Control

Batch: S419201 DMSO] 46 mg/mL] false] Ethanol] 6 mg/mL] false] Water] Insoluble] false Purity: 99.66%

99.66

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Biological Activity

Description	Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.

In vitro
In vitro	Chlorquinaldol is a derivative of hydroxy-8-quinolein. For 0.1 to 0.2% (W/V) chlorquinaldol concentrations, a reduction of about 10⁴ organisms is obtained after 60 minutes for N. gonorrhoeae and C. trachomatis. However, for technical problems, the concentrations tested are 10 to 100 times lower than the doses usually recommended for this antiseptic. ^[1] Chlorquinaldol displays enhanced bactericidal activity in duodeno-pancreatic secretions. ^[2]

References

Chemical Information & Solubility

Molecular Weight	228.07	Formula	C₁₀H₇Cl₂NO
CAS No.	72-80-0	SDF	Download Chlorquinaldol SDF
Smiles	CC1=NC2=C(C=C1)C(=CC(=C2O)Cl)Cl
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 46 mg/mL ( (201.69 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 6 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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