Aquaporin

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Isoform-selective Inhibitors

Aquaporin Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S0158 TGN020 TGN-020 (compound 9) is a selective aquaporin 4 (AQP4) inhibitor with IC50 of 3.1 μM that may have an inhibitory effect on diabetic retinal edema.
S3272 Steviol (Hydroxydehydrostevic acid) Steviol (Hydroxydehydrostevic acid, Hydroxy Dehydrostevic Acid, NSC 226902), a major metabolite of the sweetening compound stevioside, inhibits CFTR activity, reduces AQP2 expression and promotes AQP2 degradation.
S3585New Z433927330 Z433927330 is a potent and efficacious inhibitor of mouse AQP7 (Aquaporin-7) with an IC50 of ~0.2 µM. Z433927330 also inhibits mouse AQP3 (Aquaporin-3) and mouse AQP9 (Aquaporin-9) with IC50s of ~0.7 µM and ~1.1 µM, respectively.
S0158 TGN020 TGN-020 (compound 9) is a selective aquaporin 4 (AQP4) inhibitor with IC50 of 3.1 μM that may have an inhibitory effect on diabetic retinal edema.
S3272 Steviol (Hydroxydehydrostevic acid) Steviol (Hydroxydehydrostevic acid, Hydroxy Dehydrostevic Acid, NSC 226902), a major metabolite of the sweetening compound stevioside, inhibits CFTR activity, reduces AQP2 expression and promotes AQP2 degradation.
S3585New Z433927330 Z433927330 is a potent and efficacious inhibitor of mouse AQP7 (Aquaporin-7) with an IC50 of ~0.2 µM. Z433927330 also inhibits mouse AQP3 (Aquaporin-3) and mouse AQP9 (Aquaporin-9) with IC50s of ~0.7 µM and ~1.1 µM, respectively.
S3585New Z433927330 Z433927330 is a potent and efficacious inhibitor of mouse AQP7 (Aquaporin-7) with an IC50 of ~0.2 µM. Z433927330 also inhibits mouse AQP3 (Aquaporin-3) and mouse AQP9 (Aquaporin-9) with IC50s of ~0.7 µM and ~1.1 µM, respectively.