Berberine chloride

Catalog No.S2271

Berberine chloride Chemical Structure

Molecular Weight(MW): 371.81

Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids.

Size Price Stock Quantity  
In DMSO USD 90 In stock
USD 70 In stock
USD 210 In stock
USD 470 In stock
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Biological Activity

Description Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids.
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
MRC5 cells Mly2SpVv[3Srb36gZZN{[Xl? MWDBcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDDIR21XKGmwIF3SR|Uh[2WubIOgZpkheGyjcYXlJJJm\HWldHnvckBie3OjeTygTWM2OD1yLk[4JO69VQ>? NEHFd4gyPzJ|OUW5OC=>
MRC5 cells Ml7NVJJwdGmoZYLheIlwdiCjc4PhfS=> NEDtOHEyOCEQvF2= MlLUOVQhcHK| M2DEbGlvcGmkaYTpc44hd2ZiSFPNWkBxem:uaX\ldoF1cW:wIHnuJG1TSzViY3XscJMh[W[2ZYKgOVQhcHK|IIDvd5QucW6oZXP0bY9vKGG2IEGwJJVOKGK7IIDsZZF2\SCjc4PhfS=> NHTHSI4yPzJ|OUW5OC=>
MRC5 cells NIK0TlRRem:uaX\ldoF1cW:wIHHzd4F6 MmrpNVAh|ryP NWjvfYFmOjRiaB?= NH3tfJRKdmirYnn0bY9vKG:oIFjDUXYheHKxbHnm[ZJifGmxbjDpckBOWkN3IHPlcIx{KGGodHXyJFI1KGi{czDwc5N1NWmwZnXjeIlwdiCjdDCxNEB2VSCkeTDwcIFyfWViYYPzZZk> NWHuO3hsOTd{M{m1PVQ>
Bel7402 cells NGO0SmlHfW6ldHnvckBie3OjeR?= MWqxNkBp M{Xidmlv\HWldHnvckBw\iCORFzSJJBzd3SnaX6gbY4hcHWvYX6gRoVtPzRyMjDj[YxteyCjZoTldkAyOiCqcoOgZpkhWlRvUFPSJIF{e2G7IILlcIF1cX[nIITvJINwdnS{b3y= MUexPVA6ODd4Nx?=
HepG2 cells MVPGeY5kfGmxbjDhd5NigQ>? Mli1NVAhfWdxbVy= MonxNVIhcA>? NYDHcJlZUW6mdXP0bY9vKG:oIFzEUHIheHKxdHXpckBmgHC{ZYPzbY9vKGmwIHj1cYFvKEincFeyJINmdGy|IHH0JFExKHWpL33MJIFnfGW{IEGyJIhzeyCkeTDmcI94KGO7dH;t[ZRzgQ>? NVHvdFZsOTlyOUC3Olc>
KB cells M4nrcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NY\y[2piPzJiaB?= Ml34R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwQVcvOzJizszN MnzINVEyPDFzMEW=
HL60 cells M4n4SmFxd3C2b4Ppd{Bie3OjeR?= MmnpOFghcHK| NUD4V4NiUW6mdXP0bY9vKG:oIHHwc5B1d3OrczDpckBpfW2jbjDIUFYxKGOnbHzzJIFnfGW{IES4JIhzeyC3c3nu[{Bidm6neHnuJHYueHKxcHnkbZVuKGmxZHnk[UB{fGGrbnnu[{BjgSCIQVPTJIFv[Wy7c3nz NWnUNm93OjB{MkexOFQ>
A549 cells NYnldI11S3m2b4TvfIlkcXS7IHHzd4F6 NV3kVoJyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCkeTDTVmIh[XO|YYmsJGlEPTB;Nj6yO{DPxE1? MXiyNFU6PDh2OB?=
SKOV3 cells M{HPNmN6fG:2b4jpZ4l1gSCjc4PhfS=> MmrGR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2tQXjNiY3XscJMh[nliU2LCJIF{e2G7LDDJR|UxRTF4LkS0JO69VQ>? NX3OUIpPOjB3OUS4OFg>
SK-MEL-2 cells NV6zc3FlS3m2b4TvfIlkcXS7IHHzd4F6 M4rEZ2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMNU2HTD2yJINmdGy|IHL5JHNTSiCjc4PhfUwhUUN3ME2xN{44PiEQvF2= NWj4co0zOjB3OUS4OFg>
HCT15 cells NFnyO41EgXSxdH;4bYNqfHliYYPzZZk> MmraR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMh[nliU2LCJIF{e2G7LDDJR|UxRTF4LkW5JO69VQ>? MW[yNFU6PDh2OB?=
CEM cells NXLUZ2pOS3m2b4TvfIlkcXS7IHHzd4F6 NGCwUos1QCCqcoO= NFfxc|ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBETU1iY3XscJMh\XiycnXzd4lv\yCpcnXlckBndHWxcnXzZ4VvfCCycn;0[YlvKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEOFNUC9Nk4xQSEQvF2= M2fCcVIyOjl3OEmx
human CEM cells NHfuemhHfW6ldHnvckBie3OjeR?= M{WwXFch\GG7cx?= NXP0OFlbSW62aY\pdoFtKGGldHn2bZR6KGGpYXnud5QhOC5yNTDNU2khUHWvYX6gbY1ufW6xZHXmbYNq\W6leTD2bZJ2eyBzIF7MOE4{KGmwZnXjeIVlKGmwIHj1cYFvKEOHTTDj[YxteyCneIDy[ZN{cW6pIHfy[YVvKG[udX;y[ZNk\W62IIDyc5RmcW5iYYPz[ZN{\WRiYYOgdFI1KGGwdHnn[Y4heHKxZIXjeIlwdiCvZXHzeZJm\CB5IHThfZMheG:|dDDpcoZm[3Srb36gZpkhTUyLU1GsJGVEPTB;MD6xN{DPxE1? MUiyNVI6PTh7MR?=
SKN cells NHW2TY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWW3NkBp NFHCZ2dIem:5dHigbY5pcWKrdHnvckBi\2GrboP0JIh2dWGwIGPLUkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDHTVUxRTF3Lki4JO69VQ>? M4DtW|IyPDBzMUG0
RKN cells MkXvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF:wRmM1QCCqcoO= M4\ZPGdzd3e2aDDpcohq[mm2aX;uJIFo[Wmwc4SgbJVu[W5iUlvOJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFfJOVA:PDlwNjFOwG0> NX;pTHh[OjF2MEGxNVQ>
G402 cells Mn;3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYe0PEBpenN? NF3mNXlIem:5dHigbY5pcWKrdHnvckBi\2GrboP0JIh2dWGwIFe0NFIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OD1zMT64O{DPxE1? MmTLNlE1ODFzMUS=
A10 cells NE\tdGNHfW6ldHnvckBie3OjeR?= NWrHZ5Z4OzBizszN NHnCWnkzPCCqcoO= NGjj[FFFd3ewcnXneYxifGmxbjDv[kBU[2R{IH3SUmEh\XiycnXzd4lwdiCrbjDyZZQhSTFyIHPlcIx{KGG2IEOwJJVOKGGodHXyJFI1KGi{czDifUByfWGwdHn0ZZRqfmViUmStVGNTKGGwYXz5d4l{ MmT2NlE1ODFzMUS=
A10 cells MV;GeY5kfGmxbjDhd5NigQ>? M4jSclMxKM7:TR?= M1PrPFI1KGi{cx?= MXvEc5dvKHKnZ4XsZZRqd25ib3[gVJJqdTJibWLORUBmgHC{ZYPzbY9vKGmwIILheEBCOTBiY3XscJMh[XRiM{CgeW0h[W[2ZYKgNlQhcHK|IHL5JJF2[W62aYTheIl3\SCUVD3QR3Ih[W6jbInzbZM> MXOyNVQxOTFzNB?=
A10 cells M{THV2Z2dmO2aX;uJIF{e2G7 NIfIdY8{OCEQvF2= MoDBNlQhcHK| MmjaSI94dnKnZ4XsZZRqd25ib3[gTY1xcyCvUl7BJIV5eHKnc4Ppc44hcW5icnH0JGEyOCClZXzsd{BifCB|MDD1UUBi\nSncjCyOEBpenNiYomgdZVidnSrdHH0bZZmKFKWLWDDVkBidmGueYPpdy=> MWKyNVQxOTFzNB?=
HepG2-A16-CD81 cells MYjGeY5kfGmxbjDhd5NigQ>? MUexNEDPxE1? NHvrXZNPV1[DUmTJV|ohSW62aX3hcIFzcWGuIHzpeoVzKHO2YXflJIFkfGm4aYT5JI1m[XO3cnXkJIF{KGFiZ4LlZZRmeiC2aHHuJFUxLSC{ZXT1Z5Rqd25iaX6gVIxie22xZHn1cUB6d2WuaXmgd4NpcXqxboSgZZJm[SCrbjDI[ZBIOi2DMU[tR2Q5OSClZXzsd{BifCBzMIXNJINwdXCxdX7kJINwdmOnboTyZZRqd25uIHTleIVzdWmwZXSgZpkhcW2vdX7vMYZtfW:{ZYPj[Y5k\S5? M1S4OVIzODl4MUCx
HepG2-A16-CD81 cells MXzGeY5kfGmxbjDhd5NigQ>? NWDITHcyOTBizszN M1HUU25QXkGUVFnTPkBCdnSrbXHsZZJq[WxibHn2[ZIhe3SjZ3WgZYN1cX[rdImgcYVie3W{ZXSgZZMhemWmdXP0bY9vKGmwIGDsZZNud2SrdX2gfY9mdGmrIIPjbIl7d262IHHy[YEhcW5iSHXwS|IuSTF4LVPEPFEh[2WubIOgZpkhcW2vdX7vMYZtfW:{ZYPj[Y5k\SxiYX7kJI1m\GmjbjDzZ4hqgm:wdDDzbZpmKGG2IEGweW0h[2:vcH;1coQh[2:wY3XueJJifGmxbjygTWM2OD1yLkW0PEDPxE1? M320PVIzODl4MUCx
HepG2 cells Mn34SpVv[3Srb36gZZN{[Xl? M2j3eVExKM7:TR?= NXH2PHB4PCCq NIfxUGFKdmO{ZXHz[UBqdiCDTWDLZYxxcGFicHjvd5Bpd3K7bHH0bY9vKGmwIHj1cYFvKEincFeyJINmdGy|IHH0JFExKHWPIHHmeIVzKDRiaILzJIJ6KFenc4Tldo4h[myxdDDhcoFtgXOrczDy[YxifGm4ZTD0c{B2dnS{ZXH0[YQh[2:wdILvcC=> NXnqfpMyOjNyNUixNFc>
HepG2 cells MYnGeY5kfGmxbjDhd5NigQ>? NHW1dYgyOCEQvF2= M2H6WVQhcA>? M2LnVGlv[3KnYYPlJIlvKHSxdHHsJGFOWEujbIDoZUBt\X[nbDDpckBpfW2jbjDI[ZBIOiClZXzsd{BifCBzMDD1UUBi\nSncjC0JIhzeyCkeTDX[ZN1\XKwIHLsc5Qh[W6jbInzbZMhemWuYYTpeoUhfG9idX70doVifGWmIHPvcpRzd2x? NHj1[HEzOzB3OEGwOy=>
HepG2 cells M1j2RmZ2dmO2aX;uJIF{e2G7 NGjiUYczOCEQvF2= M4O0VVI1KGi{cx?= NEPxZWVKdmS3Y4Tpc44hd2ZiYYDvdJRwe2m|IHnuJIh2dWGwIFjldGczKGOnbHzzJIF{e2W|c3XkJIF{KG2xcoDoc4xw\2mlYXygZ4hidmenczDheEAzOCC3TTDh[pRmeiB{NDDodpMhfXOrbnegTI9m[2i|dDCzN|I2QCC|dHHpcolv\yCkeTDmcJVwemW|Y3XuZ4UhdWmlcn;zZ49xcWNiYX7hcJl{cXN? NUDqZWJ1OjNzOEKwPFg>
HT-29 cells NXzjToxJS3m2b4TvfIlkcXS7IHHzd4F6 NFi3VGk1QCCqcoO= NXztXodbS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFRvMkmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF05NjR3IN88US=> MU[yN|E5OjB6OB?=
HepG2 cells M{nOU2N6fG:2b4jpZ4l1gSCjc4PhfS=> NFrOO48zPCCqcoO= MmK2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME2xNU4zOiEQvF2= NVTTPIFMOjNzOEKwPFg>
HepG2 cells MkL2R5l1d3SxeHnjbZR6KGG|c3H5 NWXyNopmPDhiaILz M2jjPGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUC9PE4{OiEQvF2= NFnGT3AzOzF6MkC4PC=>

... Click to View More Cell Line Experimental Data

Protocol

References

Solubility (25°C)

In vitro DMSO 40 mg/mL (107.58 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
4% DMSO+30% PEG 300+ddH2O
For best results, use promptly after mixing.
3mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 371.81
Formula

C20H18NO4.Cl

CAS No. 633-65-8
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03770325 Not yet recruiting Cardiovascular Risk Factor The University of Hong Kong|Food and Health Bureau Hong Kong January 2019 Phase 2|Phase 3
NCT03770325 Not yet recruiting Cardiovascular Risk Factor The University of Hong Kong|Food and Health Bureau Hong Kong January 2019 Phase 2|Phase 3
NCT03438292 Recruiting Healthy University of Florida September 25 2018 Not Applicable
NCT03378934 Recruiting Coronary Artery Disease|Percutaneous Coronary Intervention Peking Union Medical College Hospital September 26 2018 Phase 4
NCT03438292 Recruiting Healthy University of Florida September 25 2018 Not Applicable
NCT03378934 Recruiting Coronary Artery Disease|Percutaneous Coronary Intervention Peking Union Medical College Hospital September 26 2018 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID