Berberine chloride

Catalog No.S2271

Berberine chloride Chemical Structure

Molecular Weight(MW): 371.81

Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids.

Size Price Stock Quantity  
In DMSO USD 90 In stock
USD 70 In stock
USD 210 In stock
USD 470 In stock
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Biological Activity

Description Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids.
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
MRC5 cells MWfGeY5kfGmxbjDhd5NigQ>? MWXBcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDDIR21XKGmwIF3SR|Uh[2WubIOgZpkheGyjcYXlJJJm\HWldHnvckBie3OjeTygTWM2OD1yLk[4JO69VQ>? MVyxO|I{QTV7NB?=
MRC5 cells MoHYVJJwdGmoZYLheIlwdiCjc4PhfS=> MkG5NVAh|ryP M175OlU1KGi{cx?= MVnJcohq[mm2aX;uJI9nKEiFTW[gdJJwdGmoZYLheIlwdiCrbjDNVmM2KGOnbHzzJIFnfGW{IEW0JIhzeyCyb4P0MYlv\mWldHnvckBifCBzMDD1UUBjgSCybHHxeYUh[XO|YYm= MYmxO|I{QTV7NB?=
MRC5 cells MkD6VJJwdGmoZYLheIlwdiCjc4PhfS=> Mn[3NVAh|ryP Ml;KNlQhcA>? NGTXNXhKdmirYnn0bY9vKG:oIFjDUXYheHKxbHnm[ZJifGmxbjDpckBOWkN3IHPlcIx{KGGodHXyJFI1KGi{czDwc5N1NWmwZnXjeIlwdiCjdDCxNEB2VSCkeTDwcIFyfWViYYPzZZk> NFLxWosyPzJ|OUW5OC=>
Bel7402 cells M1SzXWZ2dmO2aX;uJIF{e2G7 MX6xNkBp NV;zdmc6UW6mdXP0bY9vKG:oIFzEUHIheHKxdHXpckBqdiCqdX3hckBD\Wx5NECyJINmdGy|IHHmeIVzKDF{IHjyd{BjgSCUVD3QR3Ih[XO|YYmgdoVt[XSrdnWgeI8h[2:wdILvcC=> MVmxPVA6ODd4Nx?=
HepG2 cells MofESpVv[3Srb36gZZN{[Xl? MWexNEB2\y:vTB?= NFfMbHcyOiCq M4DM[2lv\HWldHnvckBw\iCORFzSJJBzd3SnaX6g[ZhxemW|c3nvckBqdiCqdX3hckBJ\XCJMjDj[YxteyCjdDCxNEB2\y:vTDDh[pRmeiBzMjDodpMh[nliZnzve{BkgXSxbXX0dpk> NWrSXJVGOTlyOUC3Olc>
KB cells NFf5R3hEgXSxdH;4bYNqfHliYYPzZZk> Mn6xO|IhcA>? MmXNR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwQVcvOzJizszN NG\OOngyOTF2MUGwOS=>
HL60 cells M3e2dWFxd3C2b4Ppd{Bie3OjeR?= MmLhOFghcHK| M4TXZ2lv\HWldHnvckBw\iCjcH;weI9{cXNiaX6gbJVu[W5iSFy2NEBk\WyuczDh[pRmeiB2ODDodpMhfXOrbnegZY5v\XirbjDWMZBzd3CrZHn1cUBqd2SrZHWgd5RicW6rbnegZpkhTkGFUzDhcoFtgXOrcx?= MljYNlAzOjdzNES=
A549 cells NHPBT41EgXSxdH;4bYNqfHliYYPzZZk> Mni3R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{BjgSCVUlKgZZN{[XluIFnDOVA:Pi5{NzFOwG0> M2\NRlIxPTl2OES4
SKOV3 cells MVLDfZRwfG:6aXPpeJkh[XO|YYm= NIrSNZNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUU0:YMzDj[YxteyCkeTDTVmIh[XO|YYmsJGlEPTB;MU[uOFQh|ryP MXmyNFU6PDh2OB?=
SK-MEL-2 cells MmfMR5l1d3SxeHnjbZR6KGG|c3H5 NGH5PVFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUUy2PRVytNkBk\WyuczDifUBUWkJiYYPzZZktKEmFNUC9NVMvPzZizszN MoraNlA2QTR6NEi=
HCT15 cells NIfpU3REgXSxdH;4bYNqfHliYYPzZZk> NWDyWlhOS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUWgZ4VtdHNiYomgV3JDKGG|c3H5MEBKSzVyPUG2MlU6KM7:TR?= MVeyNFU6PDh2OB?=
CEM cells M3fzeGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWnzbnJFPDhiaILz NVvMZ5JrS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0WPIHPlcIx{KGW6cILld5NqdmdiZ4Ll[Y4h\my3b4Lld4NmdnRicILveIVqdiCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCFQ{WwQVIvODlizszN M3izOVIyOjl3OEmx
human CEM cells NHzSc41HfW6ldHnvckBie3OjeR?= M3fJcFch\GG7cx?= MX;BcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDCwMlA2KE2RSTDIeY1idiCrbX31co9l\W[rY3nlcoN6KH[rcoXzJFEhVkx2LkOgbY5n\WO2ZXSgbY4hcHWvYX6gR2VOKGOnbHzzJIV5eHKnc4Ppcoch\3KnZX6g[ox2d3Knc3PlcpQheHKxdHXpckBie3Onc4Pl[EBieyCyMkSgZY51cWenbjDwdo9lfWO2aX;uJI1m[XO3cnXkJFch\GG7czDwc5N1KGmwZnXjeIlwdiCkeTDFUGlUSSxiRVO1NF0xNjF|IN88US=> Mm\KNlEzQTV6OUG=
SKN cells M1PJZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHzhVHI4OiCq M1G0emdzd3e2aDDpcohq[mm2aX;uJIFo[Wmwc4SgbJVu[W5iU1vOJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFfJOVA:OTVwOEig{txO M3;mZVIyPDBzMUG0
RKN cells M2rZfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGTURo81QCCqcoO= NUTGNoZiT3Kxd4ToJIlvcGmkaYTpc44h[WejaX7zeEBpfW2jbjDST24h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OD12OT62JO69VQ>? MkCwNlE1ODFzMUS=
G402 cells M1TvOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIDPTY01QCCqcoO= NEHp[mpIem:5dHigbY5pcWKrdHnvckBi\2GrboP0JIh2dWGwIFe0NFIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygS2k2OD1zMT64O{DPxE1? NXfTcYVlOjF2MEGxNVQ>
A10 cells M4LkdmZ2dmO2aX;uJIF{e2G7 M1H2SlMxKM7:TR?= NWrIeJR2OjRiaILz Mm\lSI94dnKnZ4XsZZRqd25ib3[gV4NlOiCvUl7BJIV5eHKnc4Ppc44hcW5icnH0JGEyOCClZXzsd{BifCB|MDD1UUBi\nSncjCyOEBpenNiYomgdZVidnSrdHH0bZZmKFKWLWDDVkBidmGueYPpdy=> NGL2bGYzOTRyMUGxOC=>
A10 cells MmP4SpVv[3Srb36gZZN{[Xl? NXHrcJp7OzBizszN MVSyOEBpenN? MXrEc5dvKHKnZ4XsZZRqd25ib3[gVJJqdTJibWLORUBmgHC{ZYPzbY9vKGmwIILheEBCOTBiY3XscJMh[XRiM{CgeW0h[W[2ZYKgNlQhcHK|IHL5JJF2[W62aYTheIl3\SCUVD3QR3Ih[W6jbInzbZM> MWqyNVQxOTFzNB?=
A10 cells MnPlSpVv[3Srb36gZZN{[Xl? MnHYN|Ah|ryP M4r5PFI1KGi{cx?= MlW0SI94dnKnZ4XsZZRqd25ib3[gTY1xcyCvUl7BJIV5eHKnc4Ppc44hcW5icnH0JGEyOCClZXzsd{BifCB|MDD1UUBi\nSncjCyOEBpenNiYomgdZVidnSrdHH0bZZmKFKWLWDDVkBidmGueYPpdy=> MWOyNVQxOTFzNB?=
HepG2-A16-CD81 cells M3Hj[WZ2dmO2aX;uJIF{e2G7 NXi3fVdJOTBizszN MmfXUm9XSVKWSWO6JGFvfGmvYXzhdolidCCuaY\ldkB{fGGpZTDhZ5Rqfmm2eTDt[YF{fXKnZDDhd{BiKGe{ZXH0[ZIhfGijbjC1NEUhemWmdXP0bY9vKGmwIGDsZZNud2SrdX2gfY9mdGmrIIPjbIl7d262IHHy[YEhcW5iSHXwS|IuSTF4LVPEPFEh[2WubIOgZZQhOTC3TTDjc41xd3WwZDDjc45k\W62cnH0bY9vNCCmZYTldo1qdmWmIHL5JIludXWwbz3mcJVwemW|Y3XuZ4Uv NFjTUlQzOjB7NkGwNS=>
HepG2-A16-CD81 cells NVzkNmNPTnWwY4Tpc44h[XO|YYm= M1;YblExKM7:TR?= Mly4Um9XSVKWSWO6JGFvfGmvYXzhdolidCCuaY\ldkB{fGGpZTDhZ5Rqfmm2eTDt[YF{fXKnZDDhd{Bz\WS3Y4Tpc44hcW5iUHzhd41w\Gm3bTD5c4VtcWlic3PobZpwdnRiYYLlZUBqdiCKZYDHNk1COTZvQ1S4NUBk\WyuczDifUBqdW23bn:t[ox2d3Knc3PlcoNmNCCjbnSgcYVlcWGwIIPjbIl7d262IIPpfoUh[XRiMUD1UUBkd22yb4Xu[EBkd26lZX70doF1cW:wLDDJR|UxRTBwNUS4JO69VQ>? MnP5NlIxQTZzMEG=
HepG2 cells NWDLdVBTTnWwY4Tpc44h[XO|YYm= MkXkNVAh|ryP NX:wb5RkPCCq MoLDTY5kemWjc3WgbY4hSU2SS3HsdIhiKHCqb4PwbI9zgWyjdHnvckBqdiCqdX3hckBJ\XCJMjDj[YxteyCjdDCxNEB2VSCjZoTldkA1KGi{czDifUBY\XO2ZYLuJIJtd3RiYX7hcJl{cXNicnXsZZRqfmVidH:geY51emWjdHXkJINwdnS{b3y= MVGyN|A2QDFyNx?=
HepG2 cells NEL5SIRHfW6ldHnvckBie3OjeR?= MmXpNVAh|ryP NV7KTppbPCCq NG[5[2pKdmO{ZXHz[UBqdiC2b4ThcEBCVVCNYXzwbIEhdGW4ZXygbY4hcHWvYX6gTIVxTzJiY3XscJMh[XRiMUCgeW0h[W[2ZYKgOEBpenNiYomgW4V{fGW{bjDicI91KGGwYXz5d4l{KHKnbHH0bZZmKHSxIIXueJJm[XSnZDDjc451em:u MUiyN|A2QDFyNx?=
HepG2 cells MkLLSpVv[3Srb36gZZN{[Xl? MX2yNEDPxE1? MYGyOEBpenN? MYTJcoR2[3Srb36gc4Yh[XCxcITvd4l{KGmwIHj1cYFvKEincFeyJINmdGy|IHHzd4V{e2WmIHHzJI1wenCqb3zv[4lk[WxiY3jhcodmeyCjdDCyNEB2VSCjZoTldkAzPCCqcoOgeZNqdmdiSH;lZ4h{fCB|M{K1PEB{fGGrbnnu[{BjgSCobIXvdoV{[2WwY3WgcYlkem:|Y3;wbYMh[W6jbInzbZM> MoT3NlMyQDJyOEi=
HT-29 cells M1\sfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MUS0PEBpenN? MnfQR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME24MlQ2KM7:TR?= MXuyN|E5OjB6OB?=
HepG2 cells M{X0fmN6fG:2b4jpZ4l1gSCjc4PhfS=> MX[yOEBpenN? M1\6O2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUC9NVEvOjJizszN MnXYNlMyQDJyOEi=
HepG2 cells MmTFR5l1d3SxeHnjbZR6KGG|c3H5 NXHJb2RVPDhiaILz NXTwcoVWS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF05NjN{IN88US=> NYryUY1jOjNzOEKwPFg>

... Click to View More Cell Line Experimental Data

Protocol

References

Solubility (25°C)

In vitro DMSO 40 mg/mL (107.58 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
4% DMSO+30% PEG 300+ddH2O
For best results, use promptly after mixing.
3mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 371.81
Formula

C20H18NO4.Cl

CAS No. 633-65-8
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
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Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03281096 Recruiting Drug: Berberine hydrochloride|Drug: Placebo Colorectal Adenomas xiaohua li|Xijing Hospital of Digestive Diseases August 29 2017 Phase 2|Phase 3
NCT02806999 Unknown status Drug: Berberine; Insulin|Drug: Insulin Hyperglycemia Guangdong General Hospital July 2016 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID