Proton Pump

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Inhibitory Selectivity
Solubility

Catalog No.	Product Name	Solubility(25°C)
Catalog No.	Product Name	Water	DMSO	Alcohol
S1354	Lansoprazole	<1 mg/mL	74 mg/mL	14 mg/mL
S1389	Omeprazole	<1 mg/mL	69 mg/mL	13 mg/mL
S1413	Bafilomycin A1(Baf-A1)	<1 mg/mL	6 mg/mL	<1 mg/mL
S1743	NEXIUM (esomeprazole magnesium)	<1 mg/mL	143 mg/mL	143 mg/mL
S4075	Zinc Pyrithione	<1 mg/mL	30 mg/mL	<1 mg/mL
S5658	Omeprazole Sodium	73 mg/mL	73 mg/mL	73 mg/mL
S5502	Ilaprazole sodium	-1 mg/mL	78 mg/mL	-1 mg/mL
S4845	Rabeprazole	71 mg/mL	71 mg/mL	71 mg/mL
S5058	Revaprazan Hydrochloride	-1 mg/mL	16 mg/mL	-1 mg/mL
S2222	PF-3716556	<1 mg/mL	79 mg/mL	79 mg/mL
S4099	Dexlansoprazole	<1 mg/mL	74 mg/mL	<1 mg/mL
S3666	Ilaprazole	<1 mg/mL	73 mg/mL	14 mg/mL
S4212	Tenatoprazole	<1 mg/mL	46 mg/mL	14 mg/mL
S4665	Rebeprazole sodium	76 mg/mL	76 mg/mL	76 mg/mL
S4538	Pantoprazole sodium	81 mg/mL	81 mg/mL	81 mg/mL
S2105	Pantoprazole	<1 mg/mL	76 mg/mL	76 mg/mL

Proton Pump Products

All (16) Proton Pump Inhibitors (16) New Proton Pump Products

Catalog No.	Information	Product Use Citations	Product Validations
S1354	Lansoprazole Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.
S1389	Omeprazole Omeprazole is a proton pump inhibitor, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.
S1413	Bafilomycin A1(Baf-A1) Bafilomycin A1 is a vacuolar H⁺-ATPase inhibitor with IC50 of 0.44 nM.	Immunity, 2016, 45(4):944 Cancer Lett, 2018, 431:85-95 J Exp Clin Cancer Res, 2018, 37(1):251	A549 cells and SK-1 cells co-treated with Baf A1 (100 nM) and SFN-NAC (30 μM) for 24 h, the expression of LC3 I and LC3 II was determined by Western blot.
S1743	NEXIUM (esomeprazole magnesium) Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion.
S4075	Zinc Pyrithione Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
S5658^New	Omeprazole Sodium Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion.
S5502^New	Ilaprazole sodium Ilaprazole sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor.
S4845^New	Rabeprazole Rabeprazole is an oral inhibitor of proton pump and blocks the production of acid by the stomach.
S5058^New	Revaprazan Hydrochloride Revaprazan Hydrochloride is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects.
S2222	PF-3716556 PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H⁺,K⁺-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na⁺,K⁺-ATPase, used for the treatment of gastroesophageal reflux disease.
S4099	Dexlansoprazole Dexlansoprazole, the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties.
S3666	Ilaprazole Ilaprazole is a new proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It inhibits H+/K+-ATPase with an IC50 of 6.0 μM.
S4212	Tenatoprazole Tenatoprazole is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM.
S4665	Rebeprazole sodium Rabeprazole is an antiulcer drug in the class of proton pump inhibitors.
S4538	Pantoprazole sodium Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
S2105	Pantoprazole Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

Catalog No.	Information	Product Use Citations	Product Validations
S1354	Lansoprazole Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.
S1389	Omeprazole Omeprazole is a proton pump inhibitor, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.
S1413	Bafilomycin A1(Baf-A1) Bafilomycin A1 is a vacuolar H⁺-ATPase inhibitor with IC50 of 0.44 nM.	Immunity, 2016, 45(4):944 Cancer Lett, 2018, 431:85-95 J Exp Clin Cancer Res, 2018, 37(1):251	A549 cells and SK-1 cells co-treated with Baf A1 (100 nM) and SFN-NAC (30 μM) for 24 h, the expression of LC3 I and LC3 II was determined by Western blot.
S1743	NEXIUM (esomeprazole magnesium) Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion.
S4075	Zinc Pyrithione Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
S5658^New	Omeprazole Sodium Omeprazole Sodium is the sodium salt form of omeprazole, which is a proton pump inhibitor and suppresses gastric acid secretion.
S5502^New	Ilaprazole sodium Ilaprazole sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor.
S4845^New	Rabeprazole Rabeprazole is an oral inhibitor of proton pump and blocks the production of acid by the stomach.
S5058^New	Revaprazan Hydrochloride Revaprazan Hydrochloride is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects.
S2222	PF-3716556 PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H⁺,K⁺-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na⁺,K⁺-ATPase, used for the treatment of gastroesophageal reflux disease.
S4099	Dexlansoprazole Dexlansoprazole, the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties.
S3666	Ilaprazole Ilaprazole is a new proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It inhibits H+/K+-ATPase with an IC50 of 6.0 μM.
S4212	Tenatoprazole Tenatoprazole is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM.
S4665	Rebeprazole sodium Rabeprazole is an antiulcer drug in the class of proton pump inhibitors.
S4538	Pantoprazole sodium Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
S2105	Pantoprazole Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

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