VDAC

Other Transmembrane Transporters Related Inhibitors

CFTR CRM1 Calcium Channel Proton Pump P-gp Sodium Channel ATPase Potassium Channel CD markers GLUT

Cat.No.	Product Name	Information	Product Use Citations
S7242	Erastin	Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.	Biochemical and Biophysical Research Communications, September 10, 2018, 1689-1695 PLoS One, May 12, 2016, e0154605 Oncology Letters, July 29, 2020, 57
S3544	VBIT-4	VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.	Cell Rep, 2025, 44(5):115605 Cell Rep, 2025, 44(6):115834 Aging Cell, 2025, 24(9):e70135
S8936	VBIT-12	VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.	Journal of the American Heart Association, October 28, 2025, e045554T Proceedings of the National Academy of Sciences, May 8, 2023, e2219644120 Environmental Pollution, February 15, 2022, 118720
E5770	DIDS sodium salt		Integrative Cancer Therapies, 2019, 1534735418822120
S0231	NSC15364	NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.	Exp Cell Res, 2024, 434(2):113874