VDAC

Cat.No. Product Name Information Product Use Citations Product Validations
S7242 Erastin Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.
Exp Cell Res, 2026, 454(1):114825
Nature, 2025, 10.1038/s41586-025-09741-1
Cell, 2025, S0092-8674(25)00751-2
Verified customer review of Erastin
S3544 VBIT-4 VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.
Cell Rep, 2025, 44(5):115605
Cell Rep, 2025, 44(6):115834
Aging Cell, 2025, 24(9):e70135
S8936 VBIT-12 VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.
PLoS Pathog, 2025, 21(1):e1012872
Heliyon, 2024, 10(1):e23426
Exp Cell Res, 2024, 434(2):113874
S0231 NSC15364 NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.
Exp Cell Res, 2024, 434(2):113874
E5770 DIDS sodium salt