VDAC

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VDAC Products

All (4)
VDAC Inhibitors (3)
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New VDAC Products

Catalog No.	Product Name	Information	Product Use Citations
S0231	NSC15364	NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.
S3544^New	VBIT-4	VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.	Curr Protoc, 2022, 2(2):e372
S8936^New	VBIT-12	VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.	Cell Biol Toxicol, 2021, 10.1007/s10565-021-09624-x Front Pharmacol, 2021, 12:697483
S7242	Erastin	Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions of Erastin are best fresh-prepared.	Cell Metab, 2022, 34(1):90-105.e7 Signal Transduct Target Ther, 2022, 7(1):59 Nat Cell Biol, 2022, 24(1):88-98
S0231	NSC15364	NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.
S3544^New	VBIT-4	VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.	Curr Protoc, 2022, 2(2):e372
S8936^New	VBIT-12	VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.	Cell Biol Toxicol, 2021, 10.1007/s10565-021-09624-x Front Pharmacol, 2021, 12:697483
S7242	Erastin	Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions of Erastin are best fresh-prepared.	Cell Metab, 2022, 34(1):90-105.e7 Signal Transduct Target Ther, 2022, 7(1):59 Nat Cell Biol, 2022, 24(1):88-98
S3544^New	VBIT-4	VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.	Curr Protoc, 2022, 2(2):e372
S8936^New	VBIT-12	VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.	Cell Biol Toxicol, 2021, 10.1007/s10565-021-09624-x Front Pharmacol, 2021, 12:697483