VDAC

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Catalog No. Product Name Information Product Use Citations Product Validations
S7242 Erastin Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.
Nat Commun, 2024, 15(1):1429
Genome Biol, 2024, 25(1):58
Redox Biol, 2024, 69:103002
S3544 VBIT-4 VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.
Nature, 2023, 620(7973):374-380
Acta Pharm Sin B, 2023, 13(12):4765-4784
J Autoimmun, 2023, 138:103061
S8936 VBIT-12 VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.
Heliyon, 2024, 10(1):e23426
Exp Cell Res, 2024, 434(2):113874
Mol Ther, 2022, S1525-0016-2200417-8
S0231 NSC15364 NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.
Exp Cell Res, 2024, 434(2):113874
S3544 VBIT-4 VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.
Nature, 2023, 620(7973):374-380
Acta Pharm Sin B, 2023, 13(12):4765-4784
J Autoimmun, 2023, 138:103061
S8936 VBIT-12 VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.
Heliyon, 2024, 10(1):e23426
Exp Cell Res, 2024, 434(2):113874
Mol Ther, 2022, S1525-0016-2200417-8
S0231 NSC15364 NSC 15364 (compound 59) is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization, concomitant with an inhibition of apoptosis.
Exp Cell Res, 2024, 434(2):113874
S7242 Erastin Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.
Nat Commun, 2024, 15(1):1429
Genome Biol, 2024, 25(1):58
Redox Biol, 2024, 69:103002

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