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Artemether

Name: Artemether
Brand: Selleck Chemicals
SKU: S2264
Rating: 5 (11 reviews)

Synonyms: SM-224, CGP 56696

Catalog No.S2264 Purity: 98%

Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

Artemether Chemical Structure

CAS: 71963-77-4

Selleck's Artemether has been cited by 11 Publications

1 Customer Review

Purity & Quality Control

Batch: S226401 DMSO] 60 mg/mL] false] Ethanol] 60 mg/mL] false] Water] Insoluble] false Purity: 98%

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Biological Activity

Description	Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05605925	Recruiting	Malaria	Makerere University	August 4 2022	Phase 4
NCT05343312	Active not recruiting	Malaria	Centro de Investigacao em Saude de Manhica\|United States Agency for International Development (USAID)	March 16 2022	Phase 4
NCT04708496	Recruiting	HIV Coinfection\|Malaria	Makerere University	January 18 2021	Phase 4
NCT04300309	Active not recruiting	Plasmodium Falciparum Malaria	Novartis Pharmaceuticals\|European and Developing Countries Clinical Trials Partnership (EDCTP)\|Medicines for Malaria Venture (MMV) Switzerland\|Groupe de Recherche Action en Santé (GRAS) Ouagadougou Burkina Faso\|Institut de Recherche en sciences de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN) Burkina Faso\|Novartis	December 21 2020	Phase 2\|Phase 3

Chemical Information & Solubility

Molecular Weight	298.37	Formula	C₁₆H₂₆O₅
CAS No.	71963-77-4	SDF	Download Artemether SDF
Smiles	CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 60 mg/mL ( (201.09 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 60 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
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