Artemether

Catalog No.S2264 Synonyms: SM-224, CGP 56696

For research use only.

Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

Artemether Chemical Structure

CAS No. 71963-77-4

Selleck's Artemether has been cited by 10 Publications

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Purity & Quality Control

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Biological Activity

Description Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 298.37
Formula

C16H26O5

CAS No. 71963-77-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04708496 Not yet recruiting Drug: Artemether-lumefantrine HIV Coinfection|Malaria Makerere University April 2021 Phase 4
NCT04300309 Recruiting Drug: artemether:lumefantrine (2.5 mg:30 mg) Plasmodium Falciparum Malaria Novartis Pharmaceuticals|European and Developing Countries Clinical Trials Partnership (EDCTP)|Medicines for Malaria Venture (MMV) Switzerland|Groupe de Recherche Action en Santé (GRAS) Ouagadougou Burkina Faso|Institut de Recherche en sciences de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN) Burkina Faso|Novartis December 21 2020 Phase 2|Phase 3

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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