Artemether

For research use only.

Catalog No.S2264 Synonyms: SM-224, CGP 56696

7 publications

Artemether Chemical Structure

CAS No. 71963-77-4

Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

Selleck's Artemether has been cited by 7 publications

1 Customer Review

  • Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.

    PLoS Negl Trop Dis, 2015, 9(3):e0003593.. Artemether purchased from Selleck.

Purity & Quality Control

Choose Selective ADC Cytotoxin Inhibitors

Biological Activity

Description Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

Protocol

References

Solubility (25°C)

In vitro DMSO 60 mg/mL (201.09 mM)
Ethanol 60 mg/mL (201.09 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 298.37
Formula

C16H26O5

CAS No. 71963-77-4
Storage powder
in solvent
Synonyms SM-224, CGP 56696
Smiles CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04708496 Not yet recruiting Drug: Artemether-lumefantrine HIV Coinfection|Malaria Makerere University April 2021 Phase 4
NCT04300309 Recruiting Drug: artemether:lumefantrine (2.5 mg:30 mg) Plasmodium Falciparum Malaria Novartis Pharmaceuticals|Medicines for Malaria Venture (MMV) Switzerland|Groupe de Recherche Action en Santé (GRAS) Ouagadougou Burkina Faso|Institut de Recherche en sciences de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN) Burkina Faso|Novartis December 21 2020 Phase 2|Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID