For research use only.

Catalog No.S2264 Synonyms: SM-224, CGP 56696

7 publications

Artemether Chemical Structure

CAS No. 71963-77-4

Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.

Selleck's Artemether has been cited by 7 publications

1 Customer Review

  • Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.

    PLoS Negl Trop Dis, 2015, 9(3):e0003593.. Artemether purchased from Selleck.

Purity & Quality Control

Choose Selective ADC Cytotoxin Inhibitors

Biological Activity

Description Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.



Solubility (25°C)

In vitro DMSO 60 mg/mL (201.09 mM)
Ethanol 60 mg/mL (201.09 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 298.37


CAS No. 71963-77-4
Storage powder
in solvent
Synonyms SM-224, CGP 56696
Smiles CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04708496 Not yet recruiting Drug: Artemether-lumefantrine HIV Coinfection|Malaria Makerere University April 2021 Phase 4
NCT04300309 Recruiting Drug: artemether:lumefantrine (2.5 mg:30 mg) Plasmodium Falciparum Malaria Novartis Pharmaceuticals|Medicines for Malaria Venture (MMV) Switzerland|Groupe de Recherche Action en Santé (GRAS) Ouagadougou Burkina Faso|Institut de Recherche en sciences de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN) Burkina Faso|Novartis December 21 2020 Phase 2|Phase 3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID