Amino acid transporter
- Inhibitory Selectivity
- Solubility
| Catalog No. | Product Name | Solubility(25°C) | ||
|---|---|---|---|---|
| Water | DMSO | Alcohol | ||
| S4218 | Amoxapine | <1 mg/mL | 3 mg/mL | <1 mg/mL |
| S8667 | JPH203 | <1 mg/mL | 0.01 mg/mL | <1 mg/mL |
| S8219 | Bitopertin | <1 mg/mL | 100 mg/mL | 100 mg/mL |
| S4702 | Sarcosine | 17 mg/mL | <1 mg/mL | <1 mg/mL |
- Amino acid transporter Inhibitors (4)
- New Amino acid transporter Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S4218 |
AmoxapineAmoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM. |
||
| S8667New |
JPH203JPH203, a selective L-type amino acid transporter 1 inhibitor, shows a dramatic inhibition of leucine uptake (IC50=0.06 µM) and cell growth (IC50=4.1 µM) in human colon cancer cells (HT-29), human oral cancer cells (YD-38) and leukemic cells. |
||
| S8219 |
BitopertinBitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells. |
||
| S4702 |
SarcosineSarcosine is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist. |
