Cycloguanil hydrochloride

For research use only.

Catalog No.S0320

CAS No. 152-53-4

Cycloguanil hydrochloride is an active metabolite of Proguanil. Cycloguanil hydrochloride acts on malaria schizonts in erythrocytes and hepatocytes.

Purity & Quality Control

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Biological Activity

Description Cycloguanil hydrochloride is an active metabolite of Proguanil. Cycloguanil hydrochloride acts on malaria schizonts in erythrocytes and hepatocytes.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight
Formula
CAS No. 152-53-4
Storage powder
in solvent
Synonyms N/A
Smiles CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C.Cl

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04002687 Completed Drug: ATV-PG 1000-400 mg + AQ 612 mg Malaria Medicines for Malaria Venture|Richmond Pharmacology Limited April 4 2019 Phase 1
NCT01858831 Completed Drug: Atovaquone/proguanil HCL|Drug: Atovaquone Malaria GlaxoSmithKline April 2012 Phase 1
NCT01456546 Completed Drug: Proguanil|Drug: Clopidogrel CYP2C19 Genotypes University of Southern Denmark October 2011 Phase 1

Tech Support

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DHFR Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID