Chloride Channel
Inhibitory Selectivity
Chloride Channel Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1698 |
TorsemideTorsemide is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension. |
||
| S8279 |
ShikoninShikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. |
||
| S4339New |
MeticraneMeticrane is a diuretic that inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension. |
||
| S3807 |
DehydroandrographolideDehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity. |
||
| S6470 |
FluralanerFluralaner is a systemic insecticide and acaricide that is administered orally.Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls) |
||
| S1675 |
LubiprostoneLubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation. |
||
| S1351 |
IvermectinIvermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1698 |
TorsemideTorsemide is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension. |
||
| S8279 |
ShikoninShikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. |
||
| S4339New |
MeticraneMeticrane is a diuretic that inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension. |
||
| S3807 |
DehydroandrographolideDehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity. |
||
| S6470 |
FluralanerFluralaner is a systemic insecticide and acaricide that is administered orally.Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABAA receptors) and L-glutamate-gated chloride channels (GluCls) |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1675 |
LubiprostoneLubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation. |
||
| S1351 |
IvermectinIvermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. |
