research use only

Propylparaben Anti-infection chemical

Cat.No.S5405

Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.
Propylparaben Anti-infection chemical Chemical Structure

Chemical Structure

Molecular Weight: 180.20

Quality Control

Batch: S540501 DMSO]36 mg/mL]false]Ethanol]36 mg/mL]false]Water]Insoluble]false Purity: 99.54%
99.54

Chemical Information, Storage & Stability

Molecular Weight 180.20 Formula

C10H12O3

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 94-13-3 -- Storage of Stock Solutions

Synonyms Propyl 4-hydroxybenzoate, 4-Hydroxybenzoic acid propyl ester, Propyl p-hydroxybenzoate, nipasol Smiles CCCOC(=O)C1=CC=C(C=C1)O

Solubility

In vitro
Batch:

DMSO : 36 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 36 mg/mL

Water : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02217202 Withdrawn
Osteoarthritis
Golden Jubilee National Hospital|ConvaTec Inc.
January 2050 Not Applicable
NCT04832438 Withdrawn
Salivary Gland Carcinoma|Adenoid Cystic Carcinoma|Salivary Gland Cancer|Salivary Gland Neoplasms
Actuate Therapeutics Inc.
December 18 2030 Phase 2
NCT05454306 Suspended
Clavicle Fracture
University of Minnesota
January 9 2028 Not Applicable
NCT04903795 Not yet recruiting
Malignant Glioma|Glioblastoma
Duke University
December 2026 Phase 1

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