Ceftazidime

Synonyms: GR20263

Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.

Ceftazidime Chemical Structure

Ceftazidime Chemical Structure

CAS No. 72558-82-8

Purity & Quality Control

Ceftazidime Related Products

Biological Activity

Description Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06210542 Not yet recruiting
ECMO|Carbapenem-Resistant Enterobacteriaceae Infection
Sichuan Provincial People''s Hospital
January 2024 --
NCT06089668 Recruiting
Melioidosis
AN2 Therapeutics Inc|Mahidol Oxford Tropical Medicine Research Unit
November 1 2023 --
NCT05487586 Recruiting
Hospital Acquired Pneumonia|Ventilator Acquired Pneumonia|Complicated Intra Abdominal Infections
Pfizer
October 20 2022 --
NCT05413343 Recruiting
Severe Sepsis
First Affiliated Hospital of Zhejiang University
January 1 2022 --
NCT04927312 Completed
Complicated Intra-abdominal Infection
Pfizer
October 1 2021 Phase 3

Chemical Information & Solubility

Molecular Weight 546.58 Formula

C22H22N6O7S2

CAS No. 72558-82-8 SDF Download Ceftazidime SDF
Smiles CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-]
Storage (From the date of receipt)

In vitro
Batch:

Water : 100 mg/mL

DMSO : 4 mg/mL ( (7.31 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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