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Ronidazole Anti-infection chemical

Cat.No.S4062

Ronidazole is an antiprotozoal agent. This compound is commonly used in veterinary medicine to treat infections caused by protozoa. The efficacy of this chemical has been well-documented in various studies. It is important to note that this agent should be administered under professional guidance to ensure safety and effectiveness.
Ronidazole Anti-infection chemical Chemical Structure

Chemical Structure

Molecular Weight: 200.15

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S406201 DMSO]40 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.92%
99.92

Chemical Information, Storage & Stability

Molecular Weight 200.15 Formula

C6H8N4O4

 Storage (From the date of receipt)
CAS No. 7681-76-7 -- Storage of Stock Solutions

Synonyms N/A Smiles CN1C(=CN=C1COC(=O)N)[N+](=O)[O-]

Solubility

In vitro
Batch:

DMSO : 40 mg/mL (199.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro
Ronidazole is an antiprotozoal agent used in veterinary medicine. It may also have use for the treatment of *Tritrichomonas foetus* infection in cats. This compound kills *T. foetus* at concentrations > 0.1 μg/mL *in vitro*. [1]
In vivo
Ronidazole (30 or 50 mg/kg) cures T foetus infection for follow-up durations of 21 to 30 weeks after treatment in 10/10 cats. [1]
References

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