Mechanosensitive Channel

Transmembrane Transporters

Proteasome HCV Protease HIV Protease Thrombin MMP Cysteine Protease Serine Protease Glutaminase PAD Neprilysin Cathepsin B DPP-2 Carboxypeptidase PSMA

All (1)
Mechanosensitive Channel Antagonist (1)
New Mechanosensitive Channel Products

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S2953	Dooku1	Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. This compound inhibits 2 μM Yoda1-induced Ca²⁺-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.	Sci Adv, 2023, 9(22):eadg0478
S2953	Dooku1	Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. This compound inhibits 2 μM Yoda1-induced Ca²⁺-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.	Sci Adv, 2023, 9(22):eadg0478