Mechanosensitive Channel

Choose Selective Mechanosensitive Channel Inhibitors

Mechanosensitive Channel Products

  • All (3)
  • Mechanosensitive Channel Inhibitor (1)
  • Mechanosensitive Channel Antagonist (1)
  • Mechanosensitive Channel Agonist (1)
  • New Mechanosensitive Channel Products
Catalog No. Product Name Information Product Use Citations Product Validations
P1205New GsMTx4 GsMTx4 (Grammostola spatulata mechanotoxin 4, M-theraphotoxin-Gr1a, M-TRTX-Gr1a) is a spider venom peptide that inhibits cationic mechanosensitive channels (MSCs).
S2953 Dooku1 Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.
S6678 Yoda1 Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components.
Front Cell Dev Biol, 2021, 9:741060
Front Cell Dev Biol, 2021, 9:741060
P1205New GsMTx4 GsMTx4 (Grammostola spatulata mechanotoxin 4, M-theraphotoxin-Gr1a, M-TRTX-Gr1a) is a spider venom peptide that inhibits cationic mechanosensitive channels (MSCs).
S2953 Dooku1 Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.
S6678 Yoda1 Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components.
Front Cell Dev Biol, 2021, 9:741060
Front Cell Dev Biol, 2021, 9:741060
P1205New GsMTx4 GsMTx4 (Grammostola spatulata mechanotoxin 4, M-theraphotoxin-Gr1a, M-TRTX-Gr1a) is a spider venom peptide that inhibits cationic mechanosensitive channels (MSCs).