Dehydroabietic acid

Synonyms: DAA, DHAA

Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.

Dehydroabietic acid Chemical Structure

Dehydroabietic acid Chemical Structure

CAS: 1740-19-8

Purity & Quality Control

Batch: S322601 DMSO] 100 mg/mL] false] ] ] false] ] ] false Purity: 99.45%
99.45

Dehydroabietic acid Related Products

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Biological Activity

Description Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
Targets
Src [1] Syk [1] TAK1 [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05521880 Not yet recruiting
Substance Use Disorders|Infection Soft Tissue|Bacteremia|Osteomyelitis Acute|Septic Arthritis
University of Maryland Baltimore
January 2024 Phase 4
NCT05506475 Not yet recruiting
HIV Infection|Hepatitis C Infection
Institut Pasteur|National Institute of Hygiene and Epidemiology Vietnam|ANRS Emerging Infectious Diseases
September 2023 --
NCT05992077 Not yet recruiting
HCV Infection
ANRS Emerging Infectious Diseases
August 7 2023 Not Applicable
NCT05713136 Not yet recruiting
Hepatitis C
Kirby Institute
August 14 2023 --
NCT05248555 Recruiting
Hepatitis C
Kirby Institute
January 16 2023 --

Chemical Information & Solubility

Molecular Weight 300.44 Formula

C20H28O2

CAS No. 1740-19-8 SDF --
Smiles CC(C)C1=CC2=C(C=C1)C3(C)CCCC(C)(C3CC2)C(O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (332.84 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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