BCRP
Inhibitory Selectivity
BCRP Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S6523 |
RG14620RG14620 (Tyrphostin RG14620), an EGFR inhibitor of the tyrphostin family, directly inhibits the transport function of ABCG2/BCRP. |
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| S0140 |
KS176KS176 (compound 9) is a potent and selective inhibitor of the breast cancer resistance protein (BCRP, ABCG2) multidrug transporter with IC50 of 1.39 μM and 0.59 μM in Hoechst 33342 assay and Pheo A assay, respectively. |
||
| S6715 |
YHO-13177YHO-13177, a novel acrylonitrile derivative, is a potent BCRP/ABCG2 inhibitor. |
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| S3227New |
5,7-Dimethoxyflavone5,7-Dimethoxyflavone (5,7-DMF) is an inhibitor of cytochrome P450 (CYP) 3As that markedly decreases the expression of CYP3A11 and CYP3A25 in the liver. 5,7-Dimethoxyflavone (5,7-DMF) is also a potent Breast Cancer Resistance Protein (BCRP, ABCG2) inhibitor. 5,7-Dimethoxyflavone (5,7-DMF) is one of the major components of Kaempferia parviflora with anti-obesity, anti-inflammatory, and antineoplastic effects. |
||
| S7043 |
Ko143KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2/BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S6523 |
RG14620RG14620 (Tyrphostin RG14620), an EGFR inhibitor of the tyrphostin family, directly inhibits the transport function of ABCG2/BCRP. |
||
| S0140 |
KS176KS176 (compound 9) is a potent and selective inhibitor of the breast cancer resistance protein (BCRP, ABCG2) multidrug transporter with IC50 of 1.39 μM and 0.59 μM in Hoechst 33342 assay and Pheo A assay, respectively. |
||
| S6715 |
YHO-13177YHO-13177, a novel acrylonitrile derivative, is a potent BCRP/ABCG2 inhibitor. |
||
| S3227New |
5,7-Dimethoxyflavone5,7-Dimethoxyflavone (5,7-DMF) is an inhibitor of cytochrome P450 (CYP) 3As that markedly decreases the expression of CYP3A11 and CYP3A25 in the liver. 5,7-Dimethoxyflavone (5,7-DMF) is also a potent Breast Cancer Resistance Protein (BCRP, ABCG2) inhibitor. 5,7-Dimethoxyflavone (5,7-DMF) is one of the major components of Kaempferia parviflora with anti-obesity, anti-inflammatory, and antineoplastic effects. |
||
| S7043 |
Ko143KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2/BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM. |
