research use only

Sodium Lauryl Sulfoacetate Anti-infection chemical

Name: Sodium Lauryl Sulfoacetate
Brand: Selleck Chemicals
SKU: S3801
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S3801

Sodium Lauryl Sulfoacetate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.

Chemical Structure

Molecular Weight: 330.42

Jump to

Quality Control

Batch: Purity: 99.00%

99.00

Related Targets	Integrase Bacterial Antibiotics Fungal Antiviral COVID-19 Parasite Reverse Transcriptase HIV HCV Protease
Other Anti-infection Inhibitors	Berberine chloride Clorsulon Sodium Tauroursodeoxycholate (TUDC) Cystamine dihydrochloride p-Coumaric Acid Ascomycin (FK520) LL37 (Human cathelicidin) Cinchonidine Berberine chloride hydrate Cetylpyridinium Chloride

Solubility

In vitro
Batch:

DMSO : 2 mg/mL (6.05 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	330.42	Formula	C₁₄H₂₇O₅S.Na	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	1847-58-1	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Mechanism of Action

In vitro	Treatment with Sodium Lauryl Sulfoacetate results in an increase in the expression of c-Fos protein in macrophages, while the phosphorylation level of extracellular signal-related kinase 1/2 (ERK1/2) is not affected by this compound.
In vivo	Sodium Lauryl Sulfoacetate has been shown to protect against cationized bovine serum albumin (C-BSA)-induced glomerulonephritis in BALB/C mice through the suppression of the urine protein, morphological character and monocyte chemotactic protein 1 (MCP-1). In addition, this compound treatment has been shown to induce a respiratory burst and to increase the concentration of free calcium in macrophages, as well as increase IL-2 within T-cells. This chemical in the serum, stomach and intestine can be detected immediately by GC at 0.5 h. The concentration of this compound in the stomach gradually increases from 0.5–2 h, but is drastically reduced at 4 h. Furthermore, the concentration in the serum and intestine at 1–4 h decreases in a time-dependent manner, indicating that it can be quickly absorbed into the circulatory system and intestine and might be quickly distributed to other organs, such as trachea, lung, brain, heart and kidney.
References	[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043587/ [2] https://pubmed.ncbi.nlm.nih.gov/25514406/

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):