Polyphyllin B (Formosanin C)

Catalog No.S3279 Synonyms: FC

For research use only.

Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.

Polyphyllin B (Formosanin C) Chemical Structure

CAS No. 50773-42-7

Selleck's Polyphyllin B (Formosanin C) has been cited by 1 Publication

Purity & Quality Control

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Biological Activity

Description Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 100 mg/mL
(98.5 mM)


* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 1015.18
Formula

C51H82O20

CAS No. 50773-42-7
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04896008 Not yet recruiting Drug: Sotatercept|Other: Placebo Pulmonary Arterial Hypertension Acceleron Pharma Inc. December 2021 Phase 3
NCT04934345 Not yet recruiting Diagnostic Test: Fluid challenge Fluid Challenge|Pharmakodynamic|Norepinephrine|Surgery Humanitas Clinical and Research Center September 1 2021 --
NCT04953078 Not yet recruiting Biological: Baiya SARS-CoV-2 Vax 1 Coronavirus Baiya Phytopharm Co. Ltd.|National Vaccine Institute Thailand September 2021 Phase 1
NCT04945460 Not yet recruiting Drug: Sotatercept|Drug: Placebo Cpc-PH Due to HFpEF (Combined Post-capillary and Pre-capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction) Acceleron Pharma Inc. September 2021 Phase 2
NCT04954742 Not yet recruiting Drug: Riociguat Primary Pulmonary Arterial Hypertension|Chronic Thromboembolic Pulmonary Hypertension Heidelberg University|Merck Sharp & Dohme Corp. September 2021 Phase 4

(data from https://clinicaltrials.gov, updated on 2021-09-06)

Tech Support

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