Sodium Gluconate

Catalog No.S4174

For research use only.

Sodium gluconate is the sodium salt of gluconic acid widely used in food and pharmaceutical industry.

Sodium Gluconate Chemical Structure

CAS No. 527-07-1

Purity & Quality Control

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Biological Activity

Description Sodium gluconate is the sodium salt of gluconic acid widely used in food and pharmaceutical industry.
In vitro

Sodium gluconate has the outstanding property to chelate calcium and other di-and trivalent metal ions. It is used in the bottle washing preparations, where it helps in the prevention of scale formation and its removal from glass.It is well suited for removing calcareous deposits from metals and other surfaces, including milk or beer scale on galvanised iron or stainless steel. Its property of sequestering iron over a wide range of pH is exploited in the textile industry, where it prevents the deposition of iron and for desizing polyester and polyamide fabrics. It is also used in metallurgy for alkaline derusting, as well as in the washing of painted walls and removal of metal carbonate precipitates without causing corrosion. It Also finds application as an addative to cement, controlling the setting time and increasing the strength and water resistance of the cement. It helps in the manufacture of frost and crack resistant concretes. It is also used in the household cleaning com-pounds such as mouthwashes. [1]

In vivo The diets supplemented with 4% sodium gluconate decreases weight gain and increased feed efficiency. Diets with sodium gluconate increased P and Zn retention. Diets containing sodium gluconate without phytase increased Mg retention and P content in tibia ash. The diet with 2% sodium gluconate without phytase also increased Ca retention. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

Water 44 mg/mL
(201.7 mM)
DMSO Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 218.14


CAS No. 527-07-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[Na+]

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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