Spermine

Catalog No.S3948 Synonyms: 4,9-Diaza-1,12-dodecanediamine

For research use only.

Spermine (4,9-Diaza-1,12-dodecanediamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

Spermine Chemical Structure

CAS No. 71-44-3

Selleck's Spermine has been cited by 2 Publications

Purity & Quality Control

Related Other Products

Biological Activity

Description Spermine (4,9-Diaza-1,12-dodecanediamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 40 mg/mL
(197.68 mM)


* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 202.34
Formula

C10H26N4

CAS No. 71-44-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C(CCNCCCN)CNCCCN

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04339920 Not yet recruiting Diagnostic Test: Spermine Measuring Device Prostate Cancer Chinese University of Hong Kong September 1 2021 --
NCT04518072 Recruiting Other: Blood sample (2 EDTA tube) and urine sample (100 ml) Prostate|Cancer University Hospital Montpellier|MICALIS|CBS January 6 2021 --
NCT03914391 Recruiting -- Prostate Cancer Chinese University of Hong Kong January 16 2019 --
NCT02855918 Unknown status Other: Blood sample for genetic purpose Major Depression University Hospital Montpellier|Institut National de la Santé Et de la Recherche Médicale France|Sys2Diag Mixt laboratory CNRS/Alcediag Montpellier September 2016 Not Applicable

(data from https://clinicaltrials.gov, updated on 2021-09-06)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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