Morin Hydrate

Catalog No.S2325 Synonyms: Aurantica

For research use only.

Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).

Morin Hydrate Chemical Structure

CAS No. 6202-27-3

Selleck's Morin Hydrate has been cited by 4 Publications

Purity & Quality Control

Related Other Products

Biological Activity

Description Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).
In vitro

Morin hydrate is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava). Morin hydrate as an antioxidant improves the survival time of rat glomerular mesangial cells which are attacked by oxyradicals. [1] Morin is also an effective hepatoprotector, both in cultured cells and in hepatic ischemia-reperfusion. [2] Morin hydrate is a new type of Islet Amyloid Polypeptide (IAPP) inhibitor, which may be used in type-2 diabetes and islet cell transplants. [3]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 64 mg/mL
(199.84 mM)
Ethanol 2 mg/mL warmed
(6.24 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 320.25
Formula

C15H10O7 .H2O

CAS No. 6202-27-3
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O.O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04653155 Recruiting Behavioral: Cognitive behavioural therapy for insomnia Insomnia Hospital Authority Hong Kong June 1 2020 Not Applicable
NCT04144231 Recruiting Behavioral: iCBT-I|Behavioral: GCBT-I Insomnia|Schizophrenia|Schizoaffective Disorder Helsinki University Central Hospital|University of Helsinki|Finnish Institute for Health and Welfare|Finnish Institute of Occupational Health December 19 2019 Not Applicable
NCT02272712 Active not recruiting Behavioral: Cognitive Behavioural Therapy Chronic Insomnia Ottawa Hospital Research Institute|Canadian Cancer Society (CCS)|University of Manitoba May 2014 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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