Sucralose

For research use only.

Catalog No.S4214 Synonyms: E955

1 publication

Sucralose Chemical Structure

CAS No. 56038-13-2

Sucralose (E955) is an artificial and noncaloric sweetener, not broken down by the body.

Selleck's Sucralose has been cited by 1 publication

Purity & Quality Control

Biological Activity

Description Sucralose (E955) is an artificial and noncaloric sweetener, not broken down by the body.
In vitro

Combining pea with sucrose and sucralose induced even higher levels of CCK and GLP-1. Synchronous addition of pea and sucralose to enteroendocrine cells induced higher levels of CCK and GLP-1 than addition of each compound alone.

In vivo Effects of sucralose sweetener on blood constituents labelled with technetium-99m ((99m)Tc) on red blood cell (RBC) morphology, sodium pertechnetate (Na(99m)TcO(4)) and diethylenetriaminepentaacetic acid labeled with (99m)Tc ((99m)Tc-DTPA) biodistribution in rats are evaluated. There is no alteration on RBC blood constituents and morphology %ATI. Sucralose sweetener is capable of altering %ATI/g of the radiopharmaceuticals in different organs. These findings are associated to the sucralose sweetener in specific organs.

Protocol

Solubility (25°C)

In vitro DMSO 80 mg/mL (201.19 mM)
Water 80 mg/mL (201.19 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 397.63
Formula

C12H19Cl3O8

CAS No. 56038-13-2
Storage powder
in solvent
Synonyms E955
Smiles C(C1C(C(C(C(O1)OC2(C(C(C(O2)CCl)O)O)CCl)O)O)Cl)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03986476 Active not recruiting Dietary Supplement: Probiotics|Other: Placebo IBS Örebro University Sweden March 26 2019 Not Applicable
NCT03427879 Completed Drug: Low flavonoid beverage|Drug: High flavonoid beverage Gut Permeability Gut Inflammation Utah State University September 14 2018 Phase 1
NCT03624569 Recruiting Other: Bagel|Other: Potato Cardiovascular Diseases|Endotoxemia|Endothelial Dysfunction|Postprandial Hyperglycemia|Gut Health Ohio State University|Alliance for Potato Research and Education August 15 2018 Not Applicable

Tech Support

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID