For research use only.
Catalog No.S4214 Synonyms: E955
CAS No. 56038-13-2
Sucralose (E955) is an artificial and noncaloric sweetener, not broken down by the body.
Purity & Quality Control
|Description||Sucralose (E955) is an artificial and noncaloric sweetener, not broken down by the body.|
Combining pea with sucrose and sucralose induced even higher levels of CCK and GLP-1. Synchronous addition of pea and sucralose to enteroendocrine cells induced higher levels of CCK and GLP-1 than addition of each compound alone.
|In vivo||Effects of sucralose sweetener on blood constituents labelled with technetium-99m ((99m)Tc) on red blood cell (RBC) morphology, sodium pertechnetate (Na(99m)TcO(4)) and diethylenetriaminepentaacetic acid labeled with (99m)Tc ((99m)Tc-DTPA) biodistribution in rats are evaluated. There is no alteration on RBC blood constituents and morphology %ATI. Sucralose sweetener is capable of altering %ATI/g of the radiopharmaceuticals in different organs. These findings are associated to the sucralose sweetener in specific organs.|
|In vitro||DMSO||80 mg/mL (201.19 mM)|
|Water||80 mg/mL (201.19 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation ()|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03986476||Active not recruiting||Dietary Supplement: Probiotics|Other: Placebo||IBS||Örebro University Sweden||March 26 2019||Not Applicable|
|NCT03427879||Completed||Drug: Low flavonoid beverage|Drug: High flavonoid beverage||Gut Permeability Gut Inflammation||Utah State University||September 14 2018||Phase 1|
|NCT03624569||Recruiting||Other: Bagel|Other: Potato||Cardiovascular Diseases|Endotoxemia|Endothelial Dysfunction|Postprandial Hyperglycemia|Gut Health||Ohio State University|Alliance for Potato Research and Education||August 15 2018||Not Applicable|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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