Alendronic Acid

Synonyms: alendronate

Alendronic acid (alendronate) is a nitrogen-containing, second generation bisphosphonate used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.

Alendronic Acid Chemical Structure

Alendronic Acid Chemical Structure

CAS: 66376-36-1

Selleck's Alendronic Acid has been cited by 2 publications

Purity & Quality Control

Batch: S553601 0.5MNAOH] 6.05 mg/mL] false] DMSO] Insoluble] false] Water] Insoluble] false Purity: 98%
98

Alendronic Acid Related Products

Biological Activity

Description Alendronic acid (alendronate) is a nitrogen-containing, second generation bisphosphonate used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05645289 Not yet recruiting
Postmenopausal Osteoporosis
Peking University Third Hospital
January 1 2023 Phase 4
NCT03051620 Completed
Osteoporosis
Aarhus University Hospital|University of Aarhus
February 1 2017 --
NCT02781805 Terminated
Breast Neoplasms
University of Wisconsin Madison|Wisconsin Partnership Program
August 5 2016 Phase 1

Chemical Information & Solubility

Molecular Weight 249.10 Formula

C4H13NO7P2

CAS No. 66376-36-1 SDF --
Smiles C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

0.5MNAOH : 6.05 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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