For research use only.

Catalog No.S7534

45 publications

BAPTA-AM Chemical Structure

CAS No. 126150-97-8

BAPTA-AM is a selective, membrane-permeable calcium chelator.

Selleck's BAPTA-AM has been cited by 45 publications

Purity & Quality Control

Biological Activity

Description BAPTA-AM is a selective, membrane-permeable calcium chelator.
In vitro

BAPTA-AM, as an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures. [1] BAPTA-AM exerts an open channel blocking effect on hERG, hKv1.3 and hKv1.5 channels with IC50 of 1.3, 1.45 and 1.23 μM in HEK 293 cells. [2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
SKOV3 M3LwdGZ2dmO2aX;uJIF{e2G7 MXWxNkBp NH[xb2V1emWjdH3lcpQhf2m2aDDCRXBVSS2DTTDy[YR2[2WmIITo[UBt\X[nbIOgc4YhY0OjMjvdbS=> MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODhzOUKzNEc,OzB6MUmyN|A9N2F-
OVCAR3 NUG1blNITnWwY4Tpc44h[XO|YYm= M{jMblEzKGh? NYXXT4l6fHKnYYTt[Y51KHerdHigRmFRXEFvQV2gdoVlfWOnZDD0bIUhdGW4ZXzzJI9nKFuFYUKrYYk> NE\sfnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEixPVI{OCd-M{C4NVkzOzB:L3G+
MC3T3-E1 cells NYTvOnJRTnWwY4Tpc44h[XO|YYm= Mk\mNuKh|ryP MlHYNlQhcA>? MoH2RmFRXEFxQV2gZZR1\W63YYTl[EBV\yi2aHHwd4lo[XKpaX6pMYlv\HWlZXSgUmFFWEhib4jp[IF{\SCjY4Tpeol1gQ>? MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzR3N{C3OUc,Ojd2NUewO|U9N2F-
HUVECs MkLGSpVv[3Srb36gZZN{[Xl? Ml7xOUDPxG2xbD;M NIXSbWo{KGh? MkPTcYFzc2WmbImgd5VxeHKnc4Pl[EBE[TJtIHnuZ5Jm[XOn MlnMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4NEOxOFcoRjJ3NkSzNVQ4RC:jPh?=

... Click to View More Cell Line Experimental Data

Methods Test Index PMID
Western blot
p-ERK / ERK ; 

PubMed: 23185493     

Effects of BAPTA-AM (20 µM, 30 min) on SKF83959 (30 µM, 10 min)-induced ERK1/2 phosphorylation. 

In vivo BAPTA-AM abolishes the UDCA- and TUDCA-induced increases in Ca2+ levels or Ca2+-Dependent PKC-α phosphorylation, and neutralizes the cytoprotective effects of UDCA and TUDCA on the vagotomy-induced damage of the biliary tree in the BDL rats. [3]


Animal Research:[3]
- Collapse
  • Animal Models: BDL rats
  • Dosages: ~6 mg/kg
  • Administration: i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 20 mg/mL (26.15 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 764.68


CAS No. 126150-97-8
Storage powder
in solvent
Synonyms N/A

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Related Others Products

Tags: buy BAPTA-AM | BAPTA-AM supplier | purchase BAPTA-AM | BAPTA-AM cost | BAPTA-AM manufacturer | order BAPTA-AM | BAPTA-AM distributor
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID