Molecular Weight(MW): 764.68
BAPTA-AM is a selective, membrane-permeable calcium chelator.
Cited by 21 Publications
Purity & Quality Control
|Description||BAPTA-AM is a selective, membrane-permeable calcium chelator.|
BAPTA-AM, as an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.  BAPTA-AM exerts an open channel blocking effect on hERG, hKv1.3 and hKv1.5 channels with IC50 of 1.3, 1.45 and 1.23 μM in HEK 293 cells. 
|In vivo||BAPTA-AM abolishes the UDCA- and TUDCA-induced increases in Ca2+ levels or Ca2+-Dependent PKC-α phosphorylation, and neutralizes the cytoprotective effects of UDCA and TUDCA on the vagotomy-induced damage of the biliary tree in the BDL rats. |
|In vitro||DMSO||20 mg/mL (26.15 mM)|
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