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ADP

Name: ADP
Brand: Selleck Chemicals
SKU: S9368
Availability: InStock
Rating: 5 (4 reviews)

Cat.No.S9368

ADP (Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate) is an important organic compound in metabolism and is essential to the flow of energy in living cells.

Chemical Structure

Molecular Weight: 427.20

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Quality Control

Batch: Purity: 99.96%

99.96

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Solubility

In vitro
Batch:

Water : 85 mg/mL

DMSO : 50 mg/mL (117.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	427.20	Formula	C₁₀H₁₅N₅O₁₀P₂	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	58-64-0	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate			Smiles	C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT06194799	Not yet recruiting	Alzheimer''s Disease Psychosis	ACADIA Pharmaceuticals Inc.	April 2024	Phase 3
NCT06213155	Recruiting	Trigeminal Neuralgia	St. Olavs Hospital	January 2024	Not Applicable
NCT06169319	Recruiting	Plantar Fasciitis	Endo Pharmaceuticals	December 12 2023	Phase 2
NCT06159673	Recruiting	Alzheimer''s Disease Psychosis	ACADIA Pharmaceuticals Inc.	November 14 2023	Phase 2\|Phase 3
NCT06100510	Not yet recruiting	Effect of Drug	Hematology Oncology Associates of Central New York	November 2023	Phase 4

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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