Trimetazidine

Catalog No.S5779

Trimetazidine Chemical Structure

Molecular Weight(MW): 266.34

Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.

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Biological Activity

Description Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight 266.34
Formula

C14H22N2O3

CAS No. 5011-34-7
Storage powder
in solvent
Synonyms N/A

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03504202 Not yet recruiting Patients With INOCA(Ischemia and no Obstructive Coronary Artery Disease) Who Have Coronary Microvascular Dysfunction Shanghai 10th People''s Hospital March 1 2019 Not Applicable
NCT03887013 Not yet recruiting Coronary Heart Disease|Diastolic Dysfunction China National Center for Cardiovascular Diseases March 25 2019 Phase 4
NCT03504202 Not yet recruiting Patients With INOCA(Ischemia and no Obstructive Coronary Artery Disease) Who Have Coronary Microvascular Dysfunction Shanghai 10th People''s Hospital March 1 2019 Not Applicable
NCT03887013 Not yet recruiting Coronary Heart Disease|Diastolic Dysfunction China National Center for Cardiovascular Diseases March 25 2019 Phase 4
NCT03809273 Not yet recruiting Percutaneous Coronary Intervention Shenyang Northern Hospital February 11 2019 Phase 4
NCT03809273 Not yet recruiting Percutaneous Coronary Intervention Shenyang Northern Hospital February 11 2019 Phase 4

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID