NAD+

For research use only.

Catalog No.S2518 Synonyms: β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide

1 publication

NAD+ Chemical Structure

CAS No. 53-84-9

NAD+ (β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

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Selleck's NAD+ has been cited by 1 publication

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Biological Activity

Description NAD+ (β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

Protocol

References

Solubility (25°C)

In vitro Water 100 mg/mL (150.73 mM)
DMSO Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 663.43
Formula

C21H27N7O14P2

CAS No. 53-84-9
Storage powder
in solvent
Synonyms β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide
Smiles C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04691986 Not yet recruiting Dietary Supplement: Nicotinamide Riboside|Other: Placebo Sarcopenia|Nicotinamide Adenine Dinucleotide Concentration|Muscle Quality and NAD+ Content VA Office of Research and Development|University at Buffalo May 1 2021 Not Applicable
NCT03843710 Not yet recruiting Drug: Gold Nanocrystals Amyotrophic Lateral Sclerosis Clene Nanomedicine|University of Texas Southwestern Medical Center April 30 2021 Phase 2
NCT04614714 Not yet recruiting Drug: Nicotinamide riboside chloride|Drug: Placebo Preterm Birth|Inadequate Milk Production University of California Davis December 2020 Phase 2|Phase 3
NCT04604704 Not yet recruiting Drug: Naltrexone|Dietary Supplement: NAD+ Covid19|Long COVID-19|Post-COVID-19 Syndrome AgelessRx November 2020 Phase 2
NCT04528004 Not yet recruiting Drug: Nicotinamide riboside|Other: Placebo Heart Failure Systolic|Heart Failure NYHA Class IV|Metabolic Disturbance University of Washington|National Heart Lung and Blood Institute (NHLBI) September 2020 Early Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID