Home Metabolism NADPH-oxidase chemical NAD+ (β-DPN)

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NAD+ (β-DPN) Endogenous Metabolite

Cat.No.S2518

NAD+ (β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide,nicotinamide adenine dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
NAD+ (β-DPN) NADPH-oxidase chemical Chemical Structure

Chemical Structure

Molecular Weight: 663.43

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Chemical Information, Storage & Stability

Molecular Weight 663.43 Formula

C21H27N7O14P2

 Storage (From the date of receipt)
CAS No. 53-84-9 Download SDF Storage of Stock Solutions

Synonyms β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide,nicotinamide adenine dinucleotide Smiles C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Solubility

In vitro
Batch:

Water : 50 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

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Mass Concentration Volume Molecular Weight

In vivo
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Mechanism of Action

In vitro

NAD+, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage, modulates T cell function by regulating cellular energy metabolism.[1]
References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06280482 Recruiting
Smooth Muscle Dysfunction Syndrome (SMDS)
The University of Texas Health Science Center Houston
 March 6 2024 Phase 1
NCT06005350 Recruiting
NAD
Charite University Berlin Germany|ChromaDex Inc.
 November 1 2023 Not Applicable
NCT06036355 Not yet recruiting
Postoperative Prevention of Tumor
Shanghai Cell Therapy Group Co.Ltd
 September 30 2023 Early Phase 1
NCT04691986 Recruiting
Sarcopenia|Nicotinamide Adenine Dinucleotide Concentration|Muscle Quality and NAD+ Content
VA Office of Research and Development|University at Buffalo
 September 1 2023 Not Applicable

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