4-Methylumbelliferone (4-MU)

Catalog No.S2256

For research use only.

4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.

4-Methylumbelliferone (4-MU) Chemical Structure

CAS No. 90-33-5

Selleck's 4-Methylumbelliferone (4-MU) has been cited by 2 Publications

Purity & Quality Control

Related Other Products

Biological Activity

Description 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
COS1 cells MmG2SpVv[3Srb36gZZN{[Xl? M1rJW2Fod26rc4TpZ{Bi[3Srdnn0fUB4[XNiZHX0[ZJucW6nZDDpckBEV1NzIHPlcIx{KHS{YX7z[oVkfGWmIIfpeIghT0GOIEStVHBCWiCpYX3tZUBz\WOncITvdkwhTUN3ME2wMlAzOSEQvF2= M2n0bVEzPjF5OUK0
CV-1 cells NFX1bXNHfW6ldHnvckBie3OjeR?= NVzKZZhFVWG6aX3hcEBz\XCxcoTldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDldo95cXOxbXWgdJJwdGmoZYLheI9zKGGldHn2ZZRm\CC{ZXPldJRweiCpYX3tZUBI[Wx2IHPobY1memmlIHnuJJRz[W6|aXXueIx6KHS{YX7z[oVkfGWmIFPWMVEh[2WubIOgZpkh\nWwY4Tpc45idCCjc4PhfUwhTUN3ME2wMlA1OyEQvF2= NHLMW2gyOTd{MEi1OC=>
COS-1 cells NFTQc3hHfW6ldHnvckBie3OjeR?= NIGyOZlKdiC4aYTyc{B1emGwc3HjeIl3[XSrb36gc4YhcHWvYX6gdIVzd3irc3;t[UBxem:uaX\ldoF1d3JiYXP0bZZifGWmIILlZ4VxfG:{IHfhcY1iKG2nYYP1doVlKGmwIGDQRXIuT0GONDDjbIlu\XKrYzDDU3MuOSClZXzsd{whTUN3ME2wMlAzKM7:TR?= MYexNlg4OzVzNx?=
CV-1 cells MoLvSpVv[3Srb36gZZN{[Xl? MoThRYN1cX[jdHnvckBw\iCyZYLvfIl{d22nIIDyc4xq\mW{YYTvdkBi[3SrdnH0[YQhemWlZYD0c5Ih\2GvbXGgcYVie3W{ZXSgZpkhcW6mdXP0bY9vKG:oIEWwKUBw\iCvYYjpcZVuKGGua3HsbY5mKHCqb4PwbIF1[XOnIHHjeIl3cXS7LDD0doFve2[nY4Tpc44h[XO|YYmgbY4hS1ZvMTDj[YxteyxiRVO1NF0xNjB6OUGzJO69VQ>? NEfjfm46QDN4NkKw
CV-1 cells NVnZRYRtTnWwY4Tpc44h[XO|YYm= NFfoc5RKdiC4aYTyc{B1emGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBw\iCSZYLvfIl{d22nIIDyc4xq\mW{YYTvdkBi[3SrdnH0[YQhemWlZYD0c5Ih\2GvbXGgLHBRSVJrIHX4dJJme3OnZDDpckBEXi1zIHPlcIx{NCCHQ{WwQVAvODZizszN M3nL[Fg2PzZ7MEe=
COS-1 cells NUC2[HE2TnWwY4Tpc44h[XO|YYm= MoHITY4hfmm2cn:gZYdwdmm|dDDhZ5Rqfmm2eTD0[ZN1\WRiZn;yJJRz[W6|YXP0bZZifGmxbjDpckBpfW2jbjDQVGFTKGejbX3hMWdidDRiY3jpcYVzcWNiQ1;TMVEh[2WubIOsJGVEPTB;MD6wNkDPxE1? Ml\JNVI4Ojl4Nki=
CV-1 cells Mmr4SpVv[3Srb36gZZN{[Xl? NW\udXZQUW5idnn0do8h\X[jbIXheIlwdiCjZ3HpcpN1KFK[Uj3hcJBp[S:SUFHSMYdidW2jIHnuJGNXNTFiY3XscJMh[nliY3;0doFve2[nY4Tpc44h[XO|YYmge4F{KGSndHXycYlv\WRuIFXDOVA:OC5|MkWg{txO M32xbVEzQTV2ME[x
HepG2 cells Mn7DSpVv[3Srb36gZZN{[Xl? MofkSYZn\WO2aY\lJINwdmOnboTyZZRqd25iYXfhbY5{fCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIFjldGczKGOnbHzzMEBGSzVyPUCuNFM6KM7:TR?= NXHmeGFnOTZzMEexOVA>
Huh7 cells NHTybphHfW6ldHnvckBie3OjeR?= NHX1e|VHfW6ldHnvcoFtKGGldHn2bZR6KGG2IHj1cYFvKFCSQWKg[4FudWFiaX6gTJVpPyClZXzsd{BjgSC2cnHud4FkfGm4YYTpc44h[XO|YYmsJGVEPTB;MD6yNkDPxE1? MUexOlM3PjZyMR?=
Huh7 cells M4DScWZ2dmO2aX;uJIF{e2G7 MnmxSYZn\WO2IH;uJHBRSVJiZ3HtcYEhfHKjboPhZ5RqfmG2aX;uJIFkfGm4aYT5JIlvKEi3aEegZ4VtdHNuIFXDOVA:OC5{MjFOwG0> Mo[yNVY1PTFyOEe=
U2OS cells NH3tTZZHfW6ldHnvckBie3OjeR?= M1LnVmVn\mWldDDvckBRWEGUZ3HtcYEhfHKjboPhZ5RqfmG2aX;uJIFkfGm4aYT5JIlvKFV{T2OgZ4VtdHNuIFXDOVA:OC5yMzFOwG0> MYSxOlMxODl2NB?=
CV1 cells M3;qeGZ2dmO2aX;uJIF{e2G7 NEjyfZNVemGwc3HjeIl3[XSrb36gc4YhWFCDUnfhcY1iKGmwIFPWNUBk\WyuczygSWM2OD1yLkC3OkDPxE1? M4fPZ|E3QDJzN{[5
human keratinocytes MWHQdo9tcW[ncnH0bY9vKGG|c3H5 MmHrRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCtZYLheIlvd2O7dHXzMEBGSzVyPUig{txO M3HtPVE3QDJzN{[5
HT29 cell MXTQdo9tcW[ncnH0bY9vKGG|c3H5 Mn3ZRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKVEK5JINmdGxibHnu[UwhTUN3ME20OUDPxE1? NYOxNnlvOTZ6MkG3Olk>
NIH3T3 cells NYPyNnhFTnWwY4Tpc44h[XO|YYm= M2qzNWFkfGm4aYT5JIF1KGi3bXHuJHBRSVJiZ3HtcYEhfHKjboPm[YN1\WRiaX6gUmlJO1R|IHPlcIx{KGK7IHz1Z4ln\XKjc3WgZYN1cX[rdImgZZN{[XluIFXDOVA:OC5|MjFOwG0> M4\VWFE3QDV2MEi1
CV1 cells M3fsUmZ2dmO2aX;uJIF{e2G7 NX3BVWFXXHKjboPhZ5RqfmG2aX;uJI9nKGi3bXHuJHBRSVKpYX3tZUBqdiCFVkGgZ4VtdHNiYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCHQ{WwQVAvOzB6IN88US=> NYi3OJJVOTZ7N{CzPVE>
Huh7 cells NV7BbnFnTnWwY4Tpc44h[XO|YYm= MojHRYN1cX[rdImgZZQhcHWvYX6gVHBCWiCpYX3tZUBqdiCKdXi3JINmdGy|IHL5JJRz[W6|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjJ{IN88US=> NUnvVI03OTdyM{SxOFk>
HepG2 cells MYXGeY5kfGmxbjDhd5NigQ>? Mn\uRYdwdmm|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFTKGejbX3hJIlvKGFiSHXwS|Ih[2WubIOgZpkhWFCDUj3HRWw1KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkG1PEDPxE1? NXryNHpYOTZ7N{OzOVg>
HepG2 cells Ml\1SpVv[3Srb36gZZN{[Xl? NIrEcndC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVJiZ3HtcYEhcW5iSHXwS|Ih[2WubIOgZpkhWFCDUj3HRWw1KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkG1PO69VQ>? Mki3NVY6Pzl|NEG=
CV1 cells MXjGeY5kfGmxbjDhd5NigQ>? NFrTWWFC[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEhcW5iQ2[xJINmdGy|LDDFR|UxRTBwM{C4JO69VQ>? MlKzNVcxODV|OUS=
HEK293 cells NF3EVWtHfW6ldHnvckBie3OjeR?= NH3ydVdC[3Srdnn0fUBifCCqdX3hckBi\Gmyb4PlJJRqe3O3ZTDQVGFTKGejbX3hJIV5eHKnc4Pl[EBqdiCKRVuyPVMh[2WubIOgZpkhWFCDUj3HRWw1KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkOxJO69VQ>? MlTwNVc{PDN|N{G=
rat L6 cells NFXJdHBHfW6ldHnvckBie3OjeR?= MXnF[oZm[3Rib36g[oF1fHliYXPp[EBwgGmmYYTpc44hcW5icnH0JGw3KGOnbHzzMEBGSzVyPUWg{txO NFfaeZkyPzN2M{O3NS=>
HepG2 cells Mn\CSpVv[3Srb36gZZN{[Xl? MlnERYdwdmm|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT\2GvbXGgbY4hUGWyR{KgZ4VtdHNiYomgVHBCWi2JQVy0JJRz[W6|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjB6MjFOwG0> M2TvWlE4OTV5MEG5
CV1 cells NXLtN3d5TnWwY4Tpc44h[XO|YYm= NFXUOVNC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKjbIDoZUBqdiCFVkGgZ4VtdHNiYomgS2FNPCC2cnHud4FkfGm4YYTpc44h[XO|YYmgZYZ1\XJiMkSgbJJ{NCCHQ{WwQVMvPDZizszN NH\5eIgyPzVyN{KyOS=>
CV1 cells NYL5eIl5TnWwY4Tpc44h[XO|YYm= NWPtOYNESWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEhcW5iQ2[xJINmdGy|IHL5JGdCVDRidILhcpNi[3SrdnH0bY9vKGG|c3H5JIFnfGW{IEK0JIhzeyxiRVO1NF0xNjB|IN88US=> MUSxO|UxPzJ{NR?=
CV1 cells M1z1SGZ2dmO2aX;uJIF{e2G7 M4DSXWFod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gVHBCWmejbX3hJIV5eHKnc4Pl[EBqdiCFVkGgZ4VtdHNiYomgdoVk\XC2b4KgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOzB6IN88US=> MVuxPFAzQTF5OB?=
CV1 cells NH6wN21HfW6ldHnvckBie3OjeR?= NGTXN|RC\2:waYP0JIFkfGm4aYT5JIF1KFCSQWLnZY1u[SCrbjDDWlEh[2WubIOgZpkhfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR|UxRTBwM{C4JO69VQ>? M3PEPFE4OTJ7N{K1
HEK293 cells M3fGc2Z2dmO2aX;uJIF{e2G7 NX7Ec2dCSWexbnnzeEBi[3Srdnn0fUBifCCSUFHS[4FudWFicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyCkeTDHRWw1KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkCzOUDPxE1? M4TBTFE4Ojl{NkC2
NIH3T3 cells M4O4VWZ2dmO2aX;uJIF{e2G7 NGC0U|ZC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZUBmgHC{ZYPz[YQhcW5iTlnIN3Q{KGOnbHzzJIJ6KEeDTESgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOzJizszN MVKxO|YzPDd5Nx?=
HEK293 cells MXrGeY5kfGmxbjDhd5NigQ>? MYDB[49vcXO2IHHjeIl3cXS7IHH0JHBRSVKpYX3tZUBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzJIJ6KEeDTESgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOTlizszN M{HFTFE5ODJ7MUe2
HEK293 cells NITwOoFHfW6ldHnvckBie3OjeR?= NF\HfVFC\2:waYP0JIFkfGm4aYT5JIF1KFCSQWLnZY1u[SCneIDy[ZN{\WRiaX6gTGVMOjl|IHPlcIx{KGG|c3Xzd4VlKGG|IHHQNkBo\W6nIHnu[JVkfGmxbjygSWM2OD1yLkGyJO69VQ>? M1r1WlE5ODJ7MUe2
HEK293 cells NVfOOXZZTnWwY4Tpc44h[XO|YYm= MmO1RYdwdmm|dDDhZ5Rqfmm2eTDheEBRWEGUZ3HtcYEhcW5iSFXLNlk{KGOnbHzzJIJ6KEeDTESgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvODR3IN88US=> MWmxPFI6OTZ2NR?=
HepG2 cells NHixZXdHfW6ldHnvckBie3OjeR?= NYO0TZQ1SWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUYXzwbIEhdGmpYX7kJIJqdmSrbneg[I9u[WmwIHX4dJJme3OnZDDpckBpfW2jbjDI[ZBIOiClZXzsd{Bkdy22cnHud4Zm[3SnZDD3bZRpKEejbESgZpkhdHWlaX\ldoF{\SC{ZYDvdpRmeiCpZX7lJIF{e2G7LDDFR|UxRTBwMEO5JO69VQ>? MnzwNVg5OzV5MUm=
RAW264.7 cells MnvmSpVv[3Srb36gZZN{[Xl? MYrTeZBxemW|c3nvckBw\iCOUGOvTWZPNWejbX3hMZN1cW23bHH0[YQhVk9icILv[JVkfGmxbjDpckBud3W|ZTDSRXczPjRwNzDj[YxteyxiRVO1NF0yPy53IN88US=> MkTTNVg5ODl|MkW=
BL21 cells NIDuUo9HfW6ldHnvckBie3OjeR?= MojpSIl{eGyjY3Xt[Y51KG:oIILh[IlwKGyjYnXs[YQhOiiVKT2oNk1j\W68b4nsMZBp\W67bHHtbY5wMS1|LYu0MXsyNDFvZHn0dol1cW9vMj2oOU1u\XSqeXytNk1xcGWweXytc5higm:uLUStfYwqNWW2aH;4fX0ueGinbonsgU1xem:yaX;ubYMh[WOrZDDmdo9uKEeVVD3meZNm\CCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIFXzZ4hmemmlaHnhJINwdGliQlyyNUBk\WyuczDifUB{[2mwdHnscIF1cW:wIIDyc5hqdWm2eTDhd5NigSxiRVO1NF0xNjR3IN88US=> Mkf5NVk{PDlzN{[=
BHK21 cells NYTqT2NITnWwY4Tpc44h[XO|YYm= NX\tRVh6SWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIFLIT|IyKGOnbHzzJIF{e2W|c3XkJIF{KFOHQWCgZYN1cX[rdImgZpkhdHWlaX\ldoF{\SC{ZYDvdpRmeiC2cnHud4FkfGm4YYTpc44h[XO|YYmsJGVEPTB;MD60OUDPxE1? NX3ET|B4OTl|NEmxO|Y>
HepG2/C3A cells NI\tO4xHfW6ldHnvckBie3OjeR?= NF;xWo9C[3SrdnH0bY9vKG:oIHj1cYFvKFCSQWLnZY1u[SCuaXfhcoQh[mmwZHnu[{Bld22jaX6tcYVlcWG2ZXSgeJJidnOlcnnweIlwdmGuIHHjeIl3cXS7IHnuJIh2dWGwIFjldGczN0N|QTDj[YxteyClbz30doFve2[nY4Tl[EB4cXSqIH\1d4VlKEejbEStUGJFKGK7IHPveJJidnOoZXP0bY9vKGG|c3H5MEBGSzVyPUCuNFA{QCEQvF2= M4fCZlE4PDB|Nki4
HepG2 cells NXHSdHdGTnWwY4Tpc44h[XO|YYm= NUDQWJpwSWexbnnzeEBi[3Srdnn0fUBifCCSUFHS[4FudWFiZYjwdoV{e2WmIHnuJIh2dWGwIFjldGczKGOnbHzzJIF{e2W|c3XkJIF{KGmwZIXjeIlwdiCxZjDy[YNmeHSxcjD0doFve2GldHn2ZZRqd25iYomgdoVxd3K2ZYKg[4Vv\SCjc4PhfUBz\WyjdHn2[UB1dyClb370do9tNCCHQ{WwQVAvODVizszN NVi5R2szOTh4MkW1OVk>
COS1 cells M2fBZmZ2dmO2aX;uJIF{e2G7 NGPwVY9C\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJJJm[2:vYnnuZY51KFCSQWLnZY1u[SCneIDy[ZN{\WRiaX6gR29UOSClZXzsd{Bkdy2neIDy[ZN{cW6pIFfBUFQh[XO|ZYPz[YQh[XNidILhcpNkemmydHnvcoFtKGGldHn2bZR6KGGodHXyJFQ5KGi{czDifUBtfWOrZnXyZZNmKHKncH;yeIVzKGenbnWgZZN{[XluIFXDOVA:OC5yMjFOwG0> NXrVfpZnOTl3MEe4OlE>
HepG2 cells M{f4dWZ2dmO2aX;uJIF{e2G7 NV\YW20ySWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIFjldGczKGOnbHzzJIJ6KEeDTESgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOjJ|IN88US=> NV7qNppPOTh|OUS5NFc>
CV1 cells NEDPe3ZHfW6ldHnvckBie3OjeR?= MnP4RYdwdmm|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT\2GvbXGgcIlo[W6mIHLpcoRqdmdiZH;tZYlvKGW6cILld5Nm\CCrbjDh[pJq[2GwIHfy[YVvKG2xbnvlfUBEXjFiY3XscJMh[29vdILhcpNn\WO2ZXSge4l1cCCodYPl[EBI[Wx2LVTCSEBjgSC2cnHud4FkfGm4YYTpc44h[XO|YYmsJGVEPTB;MD6wN|Mh|ryP M4C4SVE5QDJ4MkC1
CV1 cells NGH0Om1HfW6ldHnvckBie3OjeR?= NVHOVFlMSWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUYXzwbIEhdGmpYX7kJIJqdmSrbneg[I9u[WmwIHX4dJJme3OnZDDpckBi\nKrY3HuJIdz\WWwIH3vcotmgSCFVkGgZ4VtdHNiY3:teJJidnOoZXP0[YQhf2m2aDDmeZNm\CCJYXy0MWRDTCCkeTD0doFve2GldHn2ZZRqd25iYYPzZZktKEWFNUC9N{41PiEQvF2= M4[0V|E5QDJ4MkC1
U2OS cells NYiwTpFkTnWwY4Tpc44h[XO|YYm= MmDtRYdwdmm|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT\2GvbXGgbY4hXTKRUzDj[YxteyCkeTD0doFve2GldHn2ZZRqd25iYYPzZZktKEWFNUC9NE4xOiEQvF2= MVGxPFMzQTd3MR?=
Hep G2 cells MV;GeY5kfGmxbjDhd5NigQ>? MXjB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIGDQRXJo[W2vYTDsbYdidmRiYnnu[Ilv\yCmb33hbY4h\XiycnXzd4VlKGmwIHj1cYFvKEincDDHNkBk\WyuczDjc{11emGwc3\lZ5Rm\CC5aYToJGdidDRvRFLEJIJ6KGy3Y3nm[ZJie2VicnXwc5J1\XJiZ3Xu[UBie3OjeTygSWM2OD1yLkC0JO69VQ>? NGXMbYEyQTB3M{e3Oi=>
HeLa cells NHPVWYFHfW6ldHnvckBie3OjeR?= M2LaUGFod26rc4SgZYN1cX[rdImgZZQhWFCDUnfhcY1iKGyrZ3Hu[EBjcW6maX7nJIRwdWGrbjDlfJBz\XO|ZXSgbY4hcHWvYX6gTIVN[SClZXzsd{Bkdy22cnHud4Zm[3SnZDD3bZRpKEejbEStSGJFKGG|c3Xzd4VlKGG|IITyZY5{[3KrcITpc45idCCjY4TpeoF1cW:wIHL5JGdidDRicnXzdI9ve2ViZXzlcYVvfC2mcnn2[Y4hdHWlaX\ldoF{\SC{ZYDvdpRmeiCpZX7lJIF{e2G7LDDFR|UxRTBwMEG1JO69VQ>? MV:xPVI4PTl4Mx?=
COS1 cells NGLJfI9HfW6ldHnvckBie3OjeR?= NXvkUJR2SWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEhemWlZYD0c5Ih\XiycnXzd4VlKGmwIHHmdolk[W5iZ4Ll[Y4hdW:wa3X5JGNQWzFiY3XscJMh[29vdILhcpNn\WO2ZXSge4l1cCCodYPl[EB6\WG|dDDHZYw1NUSERDDifUB1emGwc3HjeIl3[XSrb36gZZN{[XluIFXDOVA:OC5yMjFOwG0> NVz6c2c4OTl3M{C2PFE>
U2OS cells M1zjbWZ2dmO2aX;uJIF{e2G7 M2L2ZWFod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gVHBCWmejbX3hJIV5eHKnc4Pl[EBqdiCXMl;TJINmdGy|IHL5JIx2[2moZYLhd4UhfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR|UxRTBwMEWg{txO NYLjdHY2OTl3N{SwOVY>
HepG2 cells NHjWZm1HfW6ldHnvckBie3OjeR?= NEfETmxC\2:waYP0JIFkfGm4aYT5JIF1KEeDTESteIFo\2WmIHj1cYFvKFCSQWLnZY1u[SCuaXfhcoQh[mmwZHnu[{Bld22jaX6g[ZhxemW|c3XkJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGG|c3Xzd4VlKGG|IILlZ4VxfG:{IITyZY5{[WO2aY\heIlwdiCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZktKEWFNUC9NE4xOzlizszN MU[xPVc4PTF4OR?=
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HEK293 cells Mme4SpVv[3Srb36gZZN{[Xl? MYqxNEDPxE1? NFrzdoszPCCqcoO= NYHTNWs4XHKjboPhZ5RqfmG2aX;uJI9nKFCSQWKt[4FudWFiKIXub45wf25ib4Lp[4lvMSCneIDy[ZN{\WRiaX6gTGVMOjl|IHPlcIx{KGG2IEGwJJVOKGGodHXyJFI1KGi{czDifUBtfWOrZnXyZZNmKHKncH;yeIVzKGenbnWgZZN{[Xl? MorzNlQ5QTByOUC=
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Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 35 mg/mL
(198.67 mM)
Ethanol 35 mg/mL
(198.67 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 176.17
Formula

C10H8O3

CAS No. 90-33-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=CC(=O)OC2=C1C=CC(=C2)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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