Orcinol glucoside

Name: Orcinol glucoside
Brand: Selleck Chemicals
SKU: S3828
Rating: 5 (1 reviews)

Synonyms: Sakakin

Catalog No.S3828 Purity: 98.92%

Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.

Orcinol glucoside Chemical Structure

CAS: 21082-33-7

Selleck's Orcinol glucoside has been cited by 1 publication

Purity & Quality Control

Batch: S382801 DMSO] 57 mg/mL] false] ] ] false] ] ] false Purity: 98.92%

98.92

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Biological Activity

Description	Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.

In Vivo
In vivo	Orcinol glucoside (OG) has an antidepressant effect in rats. OG (5, 10, and 20 mg/kg) increases the time spent in open arms and the number of entries into open arms in the elevated plus-maze test. OG (5 and 10 mg/kg) increases the number of head-dips in the hole-board test. At all tested doses, OG does not significantly affect the locomotion of mice in the open-field test. OG is anxiolytic agents without sedative effects^[1].
Animal Research	Animal Models	Male CD-1 mice
	Dosages	5, 10, or 20 mg/kg
	Administration	oral administration

References

[1] Wang X, et al. Pharm Biol. 2015, 53(6):876-81.

Chemical Information & Solubility

Molecular Weight	286.28	Formula	C₁₃H₁₈O₇
CAS No.	21082-33-7	SDF	Download Orcinol glucoside SDF
Smiles	CC1=CC(=CC(=C1)OC2C(C(C(C(O2)CO)O)O)O)O
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 57 mg/mL ( (199.1 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

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