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Ethylenediaminetetraacetic acid

Name: Ethylenediaminetetraacetic acid
Brand: Selleck Chemicals
SKU: S6350
Availability: InStock
Rating: 5 (4 reviews)

Cat.No.S6350

Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, to decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification and to inhibit protease activity. It can also decrease the formation of disulfide bonds and can also inhibit complement activation; protein protection in some immunoassays

Chemical Structure

Molecular Weight: 292.24

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Quality Control

Batch: S635001 4-Methylpyridine]5 mg/mL]true]DMSO]Insoluble]false]Water]Insoluble]false Purity: 99%

Cited in Nature Medicine for its top-tier quality
COA
SDS/MSDS
Datasheet

Related Targets	PROTAC Dyes Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Others Inhibitors	Furimazine (PBI 3939) Guanidinoacetic acid Blebbistatin Polybrene (Hexadimethrine Bromide) Silibinin (NSC 651520) Palmitic acid Carbazochrome sodium sulfonate (AC-17) 4-Methylumbelliferone (4-MU) Sesamin Osthole

Solubility

In vitro
Batch:

4-Methylpyridine : 5 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	292.24	Formula	C₁₀H₁₆N₂O₈	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	60-00-4	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Read more about storage stability stock solution CAS number

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/28099451/ [2] https://pubmed.ncbi.nlm.nih.gov/17484616/ [3] https://pubmed.ncbi.nlm.nih.gov/21272559/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-06-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07631364	NOT_YET_RECRUITING	Neisseria Gonorrhoeae (Ng) Infections	Assistance Publique - Hôpitaux de Paris	2026-09	PHASE3
NCT07191262	RECRUITING	Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth	University of Alabama at Birmingham	2026-03-02
NCT05879835	RECRUITING	Pediatric Intestinal Failure	SterileCare Inc.	2024-06-21
NCT06386991	UNKNOWN	Endodontic Disease	TC Erciyes University	2024-01-01	PHASE4
NCT05878249	UNKNOWN	Reversible Pulpitis	Postgraduate Institute of Dental Sciences Rohtak	2022-11-01
NCT06016088	Recruiting	Cystic Fibrosis Lung\|Respiratory Infections Recurrent Chronic\|Pseudomonas Aeruginosa	Respirion Pharmaceuticals Pty Ltd	2024-04-01	Phase 1\|Phase 2

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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