Chlorogenic Acid

Catalog No.S2280 Synonyms: NSC 407296, Heriguard

For research use only.

Chlorogenic acid (NSC 407296, Heriguard) is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.

Chlorogenic Acid Chemical Structure

CAS No. 327-97-9

Selleck's Chlorogenic Acid has been cited by 4 Publications

Purity & Quality Control

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Biological Activity

Description Chlorogenic acid (NSC 407296, Heriguard) is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 354.31
Formula

C16H18O9

CAS No. 327-97-9
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03520452 Completed Other: Green coffee extract|Other: Placebo Endothelial Dysfunction Nestlé March 14 2018 Not Applicable
NCT02728349 Completed Drug: Chlorogenic acid Glioblastoma Sichuan J.Z. Bio-chemical Science and Technology Development Co. Ltd|Beijing Shijitan Hospital Capital Medical University April 12 2016 Phase 1
NCT02245204 Completed Drug: Chlorogenic acid Advanced Cancer Sichuan J.Z. Bio-chemical Science and Technology Development Co. Ltd|Beijing Cancer Hospital September 2014 Phase 1
NCT02136342 Terminated Drug: chlorogenic acid Advanced Cancer Chinese Academy of Medical Sciences|Sichuan J.Z. Bio-chemical Science and Technology Development Co. Ltd May 2014 Phase 1
NCT01912144 Completed Other: Coffee Bioavailability|Cardiovascular Health Status University of Leeds September 1 2012 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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