research use only
Cat.No.S3992
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In vitro |
Water : 76 mg/mL
DMSO
: 75 mg/mL
(198.23 mM)
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In vivo |
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Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.
| Molecular Weight | 378.33 | Formula | C12 H22O11 . 2H2O |
Storage (From the date of receipt) | |
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| CAS No. | 6138-23-4 | -- | Storage of Stock Solutions |
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| Synonyms | N/A | Smiles | C(C1C(C(C(C(O1)OC2C(C(C(C(O2)CO)O)O)O)O)O)O)O.O.O | ||
| In vitro |
Trehalose has been shown to play a key role in various types of stress-tolerance including radiation, cold and dehydration stresses in bacteria, yeast, nematodes, rotifers, tardigrades, certain crustaceans and insects. Studies on the role of trehalose in stress-tolerance suggest that trehalose must be presence on both sides of the cell membrane to confer protection. It is a non-charged and hydrophilic disaccharide which does not freely penetrate the mammalian cell membrane without external interventions.
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References |
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