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Sodium succinate

Cat.No.S5433

Sodium succinate (Sodium 3-carboxypropanoate, Disodium butanedioate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxygen species.
Sodium succinate Chemical Structure

Chemical Structure

Molecular Weight: 162.05

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Quality Control

Batch: S543301 Water]32 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 98%
98

Solubility

In vitro
Batch:

Water : 32 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

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In vivo
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 162.05 Formula

C4H4O4.2Na

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 150-90-3 -- Storage of Stock Solutions

Synonyms Sodium 3-carboxypropanoate, Disodium butanedioate SMILES C(CC(=O)[O-])C(=O)[O-].[Na+].[Na+]

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Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-08-31)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04877288 RECRUITING
Renal Allograft Recipients
Bristol-Myers Squibb
 2021-07-21 PHASE3
NCT07055087 NOT_YET_RECRUITING
Parkinson's Disease
University Hospital Tuebingen
 2025-12 PHASE2
NCT06364930 RECRUITING
Chronic Hepatitis B
Chinese University of Hong Kong
 2024-03-26 PHASE4
NCT06625073 RECRUITING
Heart Transplant; Cardiovascular Disease; Kidney Disease
VA Office of Research and Development
 2026-01-20 PHASE4
NCT06190158 ACTIVE_NOT_RECRUITING
Type 2 Diabetes; Chronic Kidney Diseases
Brigham and Women's Hospital
 2024-05-15 EARLY_PHASE1
NCT06870448 NOT_YET_RECRUITING
Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
 2025-04 PHASE3

Read more about Clinical Trials

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