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Ropivacaine

Cat.No.S5504

Ropivacaine is a member of the amino amide class of local anesthetics.
Ropivacaine Chemical Structure

Chemical Structure

Molecular Weight: 274.40

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S550401 DMSO]23 mg/mL]false]Water]Insoluble]false]]]false Purity: 99.99%
99.99

Chemical Information, Storage & Stability

Molecular Weight 274.40 Formula

C17H26N2O

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 84057-95-4 -- Storage of Stock Solutions

Synonyms N/A Smiles CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C

Solubility

In vitro
Batch:

DMSO : 23 mg/mL (83.81 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04003506 Not yet recruiting
Pain Postoperative
The University of Hong Kong
 March 1 2024 Phase 4
NCT06006026 Recruiting
Colorectal Cancer
West China Hospital
 August 28 2023 Not Applicable
NCT05773846 Recruiting
Bunion
PainReform LTD|Lotus Clinical Research LLC
 March 13 2023 Phase 3

Tech Support

Handling Instructions

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