Inulin

Catalog No.S2609

Inulin Chemical Structure

Molecular Weight(MW): N/A

Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.

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Biological Activity

Description Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.
In vitro

Inulin causes (20 g/d and 40 g/d) a significant increase in bifidobacterial counts in feces.[1] Inulin exerts a preferential stimulatory effect on numbers of the health-promoting genus Bifidobacterium, whilst maintaining populations of potential pathogens (Escherichia coli, Clostridium) at relatively low levels. [2] Inulin combined with Bifidobacterium results in more potent inhibition of aberrant crypt foci (ACF) than administration of the two separately, achieving 80% inhibition of small ACF. [3] Inulin is made by a set of linear chains of fructose molecules, with a degree of polymerization (DP) ranging between 3 and 65, it can be fractionated into a slowly fermentable long-chain fraction (DP ranging from 10 to 65, average 25) or in a rapidly fermentable fraction made of oligofructose (DP ranging from 3 to 8, average 4). [4] Long-chain inulin combined with short-chain oligofructose results in larger numbers of caecal, colonic and faecal bacteria of the Clostridium coccoides-Eubacterium rectale cluster than Control in rats, whereas OF alone does not affect this bacterial group in caecum, colon or faeces. [5]

In vivo Inulin results in an increase in caecal wt and beta-glucosidase activity and a decrease in caecal pH were observed in rats given inulin-containing diets (with or without B. longum). [3]

Protocol

Solubility (25°C)

In vitro Water 104 mg/mL
DMSO 10 mg/mL
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight N/A
Formula

C6nH10n+2O5n+1

CAS No. 9005-80-5
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03983434 Not yet recruiting Dietary Supplement: Inulin IBS - Irritable Bowel Syndrome Indiana University|National Institutes of Health (NIH) September 1 2019 --
NCT02729662 Active not recruiting Drug: Tolvaptan Autosomal Dominant Polycystic Kidney Disease Kyorin University October 1 2016 Not Applicable
NCT02846454 Recruiting Other: inulin|Other: arabinoxylan Overweight and Obesity University of Reading August 2016 Not Applicable
NCT03265639 Completed Dietary Supplement: P-inulin End Stage Renal Disease|Gut Microbiome Dysbiosis Ali Ramezani|George Washington University April 21 2016 Not Applicable

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID