Potassium Iodide

Name: Potassium Iodide
Brand: Selleck Chemicals
SKU: S1897
Rating: 5 (1 reviews)

Catalog No.S1897 Purity: 99%

Potassium Iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine.

Potassium Iodide Chemical Structure

CAS: 7681-11-0

Purity & Quality Control

Content >99%
Finest quality approved by Nature Medicine
COA
Datasheet
SDS

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Biological Activity

Description	Potassium Iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine.

In vitro
In vitro	Iodine induces abnormal morphologic changes of cells, inhibited cell proliferation, and increases apoptosis rate in rat aorta endothelial cells. Iodine also reduces the activity of SOD, GSH-Px, and concentrations of GSH and increases the concentrations of MDA and protein carbonyl in a dose-dependent manner. Excess iodine decreased the activity of eNOS and increased the activity of iNOS and the expression of ICAM-1 and VCAM-1 in culture medium. Excess iodine exposure increases oxidative stress, causes damage of vascular endothelial cells, and altered the expression of adhesion factors and the activity of NOS. ^[1] Potassium iodide increases avidity of some immune reactions including C-mediated cell lysis mediated by altered access of C-binding receptors. ^[2] Potassium iodide (≥50 mM) increases lipid peroxidation in concentration-dependent manner. Potassium iodide (25 mM) reduces Fenton reaction-induced lipid peroxidation. ^[3] Potassium iodide is able to eliminate E faecalis from bovine root dentin when used with a 15-minute contact time. ^[4]

In Vivo
In vivo	Potassium Iodide decreases Schiff's bases (SB) concentrations in liver and lung homogenates after the administration of PTU but, unexpectedly, the level of SB increases in kidney homogenates of Wistar rats. ^[5]

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT01301768	Withdrawn	Dietary Intervention\|Pregnancy Jail\|Iodine Deficiency	Fundacio d''Investigacio en Atencio Primaria Jordi Gol i Gurina	November 2008	Not Applicable
NCT00379535	Terminated	Pregnancy	University Hospital Toulouse\|Ministry of Health France	December 2006	Phase 3

References

[4] Baker NE, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2004, 98(3), 359-364.
[5] Sewerynek E, et al. Neuro Endocrinol Lett, 2006, 27(5), 595-599.

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Chemical Information & Solubility

Molecular Weight	166	Formula	K⁺I^-
CAS No.	7681-11-0	SDF	Download Potassium Iodide SDF
Smiles	[K+].[I-]
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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