4-Methylumbelliferone (4-MU)

Name: 4-Methylumbelliferone (4-MU)
Brand: Selleck Chemicals
SKU: S2256
Rating: 5 (2 reviews)

For research use only.

Catalog No.S2256

2 publications

4-Methylumbelliferone (4-MU) Chemical Structure

CAS No. 90-33-5

4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.

Selleck's 4-Methylumbelliferone (4-MU) has been cited by 2 publications

Mol Carcinog, 2019, 58(3):321-333

PubMed: 30365189 ( click the link to review the publication )

J Med Virol, 2019, 91(8):1440-1447

PubMed: 30900754 ( click the link to review the publication )

Purity & Quality Control

Biological Activity

Description

4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Activity Description	PMID
COS1 cells	Mlj4SpVv[3Srb36gZZN{[Xl?			MmHNRYdwdmm\|dHnjJIFkfGm4aYT5JJdieyCmZYTldo1qdmWmIHnuJGNQWzFiY3XscJMhfHKjboPm[YN1\WRid3n0bEBISUxiND3QVGFTKGejbX3hJJJm[2WydH;yMEBGSzVyPUCuNFIyKM7:TR?=	MoLtNVI3OTd7MkS=
CV-1 cells	NF;QRlBHfW6ldHnvckBie3OjeR?=			M3\4Om1igGmvYXygdoVxd3K2ZYKgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCSZYLvfIl{d22nIIDyc4xq\mW{YYTvdkBi[3SrdnH0[YQhemWlZYD0c5Ih\2GvbXGgS4FtPCClaHnt[ZJq[yCrbjD0doFve2mnboTsfUB1emGwc3\lZ5Rm\CCFVj2xJINmdGy\|IHL5JIZ2dmO2aX;uZYwh[XO\|YYmsJGVEPTB;MD6wOFMh\|ryP	MXyxNVczODh3NB?=
COS-1 cells	MV7GeY5kfGmxbjDhd5NigQ>?			NInNcHhKdiC4aYTyc{B1emGwc3HjeIl3[XSrb36gc4YhcHWvYX6gdIVzd3irc3;t[UBxem:uaX\ldoF1d3JiYXP0bZZifGWmIILlZ4VxfG:{IHfhcY1iKG2nYYP1doVlKGmwIGDQRXIuT0GONDDjbIlu\XKrYzDDU3MuOSClZXzsd{whTUN3ME2wMlAzKM7:TR?=	NET6coMyOjh5M{WxOy=>
CV-1 cells	M2rrc2Z2dmO2aX;uJIF{e2G7			MWPBZ5RqfmG2aX;uJI9nKHCncn;4bZNwdWVicILvcIln\XKjdH;yJIFkfGm4YYTl[EBz\WOncITvdkBo[W2vYTDt[YF{fXKnZDDifUBqdmS3Y4Tpc44hd2ZiNUClJI9nKG2jeHnteY0h[WytYXzpcoUheGixc4DoZZRie2ViYXP0bZZqfHluIITyZY5{\mWldHnvckBie3OjeTDpckBEXi1zIHPlcIx{NCCHQ{WwQVAvODh7MUOg{txO	M3n1OFk5OzZ4MkC=
CV-1 cells	NWTqWXdyTnWwY4Tpc44h[XO\|YYm=			NXruOVY3UW5idnn0do8hfHKjboPjdolxfGmxbnHsJIFkfGm4YYTpc44hd2ZiUHXyc5hqe2:vZTDwdo9tcW[ncnH0c5Ih[WO2aY\heIVlKHKnY3XweI9zKGejbX3hJEhRWEGUKTDlfJBz\XO\|ZXSgbY4hS1ZvMTDj[YxteyxiRVO1NF0xNjB4IN88US=>	NYPTOGFxQDV5NkmwOy=>
COS-1 cells	Mn7CSpVv[3Srb36gZZN{[Xl?			M13VSWlvKH[rdILvJIFod26rc4SgZYN1cX[rdImgeIV{fGWmIH\vdkB1emGwc3HjeIl3[XSrb36gbY4hcHWvYX6gVHBCWiCpYX3tZU1I[Wx2IHPobY1memmlIFPPV{0yKGOnbHzzMEBGSzVyPUCuNFIh\|ryP	M{G3c\|EzPzJ7Nk[4
CV-1 cells	NXK5dpBCTnWwY4Tpc44h[XO\|YYm=			NFXJNmJKdiC4aYTyc{BmfmGudXH0bY9vKGGpYXnud5QhWliULXHsdIhiN1CSQWKt[4FudWFiaX6gR3YuOSClZXzsd{BjgSClb4TyZY5{\mWldHnvckBie3OjeTD3ZZMh\GW2ZYLtbY5m\CxiRVO1NF0xNjN{NTFOwG0>	NGHmNpcyOjl3NEC2NS=>
HepG2 cells	MknySpVv[3Srb36gZZN{[Xl?			M4fiV2Vn\mWldHn2[UBkd26lZX70doF1cW:wIHHnZYlve3RiaIXtZY4hWFCDUnfhcY1iKGW6cILld5Nm\CCrbjDI[ZBIOiClZXzsd{whTUN3ME2wMlA{QSEQvF2=	MonMNVYyODdzNUC=
Huh7 cells	NU\UfFg5TnWwY4Tpc44h[XO\|YYm=			Ml7TSpVv[3Srb37hcEBi[3Srdnn0fUBifCCqdX3hckBRWEGUIHfhcY1iKGmwIFj1bFch[2WubIOgZpkhfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR\|UxRTBwMkKg{txO	NHvZdYsyPjN4Nk[wNS=>
Huh7 cells	MV3GeY5kfGmxbjDhd5NigQ>?			MVXF[oZm[3Rib36gVHBCWiCpYX3tZUB1emGwc3HjeIl3[XSrb36gZYN1cX[rdImgbY4hUHWqNzDj[YxteyxiRVO1NF0xNjJ{IN88US=>	NIm5OlEyPjR3MUC4Oy=>
U2OS cells	MVnGeY5kfGmxbjDhd5NigQ>?			NWLG[WVnTW[oZXP0JI9vKFCSQWLnZY1u[SC2cnHud4FkfGm4YYTpc44h[WO2aY\peJkhcW5iVULPV{Bk\WyuczygSWM2OD1yLkCzJO69VQ>?	NHPJfFIyPjNyMEm0OC=>
CV1 cells	NXjmVVNOTnWwY4Tpc44h[XO\|YYm=			NHTnW4tVemGwc3HjeIl3[XSrb36gc4YhWFCDUnfhcY1iKGmwIFPWNUBk\WyuczygSWM2OD1yLkC3OkDPxE1?	MkjsNVY5OjF5Nkm=
human keratinocytes	M1P4NnBzd2yrZnXyZZRqd25iYYPzZZk>			NILXeJlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIHvldoF1cW6xY4n0[ZMtKEWFNUC9PEDPxE1?	M4fJc\|E3QDJzN{[5
HT29 cell	MYLQdo9tcW[ncnH0bY9vKGG\|c3H5			NWTuVpc6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWFI6KGOnbHygcIlv\SxiRVO1NF01PSEQvF2=	NYfRPYhiOTZ6MkG3Olk>
NIH3T3 cells	MV;GeY5kfGmxbjDhd5NigQ>?			NEftWmlC[3Srdnn0fUBifCCqdX3hckBRWEGUIHfhcY1iKHS{YX7z[oVkfGWmIHnuJG5KUDOWMzDj[YxteyCkeTDseYNq\mW{YYPlJIFkfGm4aYT5JIF{e2G7LDDFR\|UxRTBwM{Kg{txO	Ml;PNVY5PTRyOEW=
CV1 cells	MWHGeY5kfGmxbjDhd5NigQ>?			M13IRnRz[W6\|YXP0bZZifGmxbjDv[kBpfW2jbjDQVGFT\2GvbXGgbY4hS1ZzIHPlcIx{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlMxQCEQvF2=	NIS4OI8yPjl5MEO5NS=>
Huh7 cells	NH;2c5hHfW6ldHnvckBie3OjeR?=			MWjBZ5Rqfmm2eTDheEBpfW2jbjDQVGFTKGejbX3hJIlvKEi3aEegZ4VtdHNiYomgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOjJizszN	NXfvZpdHOTdyM{SxOFk>
HepG2 cells	MmfhSpVv[3Srb36gZZN{[Xl?			MkiwRYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFTKGejbX3hJIlvKGFiSHXwS\|Ih[2WubIOgZpkhWFCDUj3HRWw1KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkG1PEDPxE1?	NVHvfZI3OTZ7N{OzOVg>
HepG2 cells	M3v1XmZ2dmO2aX;uJIF{e2G7			M4XYNWFod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gVHBCWiCpYX3tZUBqdiCKZYDHNkBk\WyuczDifUBRWEGULVfBUFQhfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR\|UxRTBwMUW4{txO	NX3rc2RpOTZ7N{mzOFE>
CV1 cells	NHjhWmxHfW6ldHnvckBie3OjeR?=			M4PyNGFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZUBqdiCFVkGgZ4VtdHNuIFXDOVA:OC5\|MEig{txO	MXexO\|AxPTN7NB?=
HEK293 cells	M33vWWZ2dmO2aX;uJIF{e2G7			MofwRYN1cX[rdImgZZQhcHWvYX6gZYRqeG:\|ZTD0bZN{fWViUGDBVkBo[W2vYTDlfJBz\XO\|ZXSgbY4hUEWNMkmzJINmdGy\|IHL5JHBRSVJvR1HMOEB1emGwc3HjeIl3[XSrb36gZZN{[XluIFXDOVA:OC5\|MTFOwG0>	M2P0bVE4OzR\|M{ex
rat L6 cells	NYDLb3dUTnWwY4Tpc44h[XO\|YYm=			M3nCc2Vn\mWldDDvckBn[XS2eTDhZ4llKG:6aXTheIlwdiCrbjDyZZQhVDZiY3XscJMtKEWFNUC9OUDPxE1?	NEHMcosyPzN2M{O3NS=>
HepG2 cells	M{XaU2Z2dmO2aX;uJIF{e2G7			NELwflhC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZUBqdiCKZYDHNkBk\WyuczDifUBRWEGULVfBUFQhfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR\|UxRTBwMEiyJO69VQ>?	NULleYI3OTdzNUewNVk>
CV1 cells	NFO4O5VHfW6ldHnvckBie3OjeR?=			NW\4eoQ6SWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUYXzwbIEhcW5iQ2[xJINmdGy\|IHL5JGdCVDRidILhcpNi[3SrdnH0bY9vKGG\|c3H5JIFnfGW{IEK0JIhzeyxiRVO1NF0{NjR4IN88US=>	MWGxO\|UxPzJ{NR?=
CV1 cells	Mn76SpVv[3Srb36gZZN{[Xl?			NXTufFlESWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEhcW5iQ2[xJINmdGy\|IHL5JGdCVDRidILhcpNi[3SrdnH0bY9vKGG\|c3H5JIFnfGW{IEK0JIhzeyxiRVO1NF0xNjB\|IN88US=>	Ml24NVc2ODd{MkW=
CV1 cells	MlPWSpVv[3Srb36gZZN{[Xl?			M4\sVWFod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gVHBCWmejbX3hJIV5eHKnc4Pl[EBqdiCFVkGgZ4VtdHNiYomgdoVk\XC2b4KgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOzB6IN88US=>	M3robFE5ODJ7MUe4
CV1 cells	Mk\ySpVv[3Srb36gZZN{[Xl?			NUG5dXRvSWexbnnzeEBi[3Srdnn0fUBifCCSUFHS[4FudWFiaX6gR3YyKGOnbHzzJIJ6KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkOwPEDPxE1?	M3W0O\|E4OTJ7N{K1
HEK293 cells	MoHKSpVv[3Srb36gZZN{[Xl?			M1K0UmFod26rc4SgZYN1cX[rdImgZZQhWFCDUnfhcY1iKHKnY3XweI9zKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMh[nliR1HMOEB1emGwc3HjeIl3[XSrb36gZZN{[XluIFXDOVA:OC5yM{Wg{txO	MojGNVczQTJ4ME[=
NIH3T3 cells	M2\VWGZ2dmO2aX;uJIF{e2G7			NUDYToJHSWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIF7JTFNVOyClZXzsd{BjgSCJQVy0JJRz[W6\|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjN{IN88US=>	NITRZVIyPzZ{NEe3Oy=>
HEK293 cells	Mo\1SpVv[3Srb36gZZN{[Xl?			NW\ucFQ5SWexbnnzeEBi[3Srdnn0fUBifCCSUFHS[4FudWFiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyCkeTDHRWw1KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1yLkG5JO69VQ>?	M1[3XlE5ODJ7MUe2
HEK293 cells	NF3DU5JHfW6ldHnvckBie3OjeR?=			NID4VnVC\2:waYP0JIFkfGm4aYT5JIF1KFCSQWLnZY1u[SCneIDy[ZN{\WRiaX6gTGVMOjl\|IHPlcIx{KGG\|c3Xzd4VlKGG\|IHHQNkBo\W6nIHnu[JVkfGmxbjygSWM2OD1yLkGyJO69VQ>?	NIfHO5IyQDB{OUG3Oi=>
HEK293 cells	NFvDVpVHfW6ldHnvckBie3OjeR?=			MlrCRYdwdmm\|dDDhZ5Rqfmm2eTDheEBRWEGUZ3HtcYEhcW5iSFXLNlk{KGOnbHzzJIJ6KEeDTESgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvODR3IN88US=>	NWntcoZLOTh{OUG2OFU>
HepG2 cells	NVjxZYM6TnWwY4Tpc44h[XO\|YYm=			MlqyRYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT[WyyaHGgcIlo[W6mIHLpcoRqdmdiZH;tZYlvKGW6cILld5Nm\CCrbjDoeY1idiCKZYDHNkBk\WyuczDjc{11emGwc3\lZ5Rm\CC5aYToJGdidDRiYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCHQ{WwQVAvODN7IN88US=>	NVO4OIg2OTh6M{W3NVk>
RAW264.7 cells	MYHGeY5kfGmxbjDhd5NigQ>?			MU\TeZBxemW\|c3nvckBw\iCOUGOvTWZPNWejbX3hMZN1cW23bHH0[YQhVk9icILv[JVkfGmxbjDpckBud3W\|ZTDSRXczPjRwNzDj[YxteyxiRVO1NF0yPy53IN88US=>	MVexPFgxQTN{NR?=
BL21 cells	M{OyXmZ2dmO2aX;uJIF{e2G7			M4XPb2Rqe3CuYXPlcYVvfCCxZjDyZYRqdyCuYXLlcIVlKDJqUzmtLFIu[mWwen;5cE1xcGWweXzhcYlvdylvMz37OE1cOSxzLXTpeJJqfGmxLUKtLFUudWW2aInsMVIueGinbonsMY95[XqxbD20MZltMS2ndHjvfJleNXCqZX75cJ0ueHKxcHnvcolkKGGlaXSg[pJwdSCJU2St[pV{\WRiaIXtZY4hWFCDUnfhcY1iKGW6cILld5Nm\CCrbjDFd4Np\XKrY3jpZUBkd2yrIFLMNlEh[2WubIOgZpkhe2OrboTpcIxifGmxbjDwdo95cW2rdImgZZN{[XluIFXDOVA:OC52NTFOwG0>	MXyxPVM1QTF5Nh?=
BHK21 cells	MVjGeY5kfGmxbjDhd5NigQ>?			MU\B[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIGDQRXJo[W2vYTDlfJBz\XO\|ZXSgbY4hSkiNMkGgZ4VtdHNiYYPz[ZN{\WRiYYOgV2VCWCCjY4Tpeol1gSCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJJRz[W6\|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjR3IN88US=>	NIHFPZoyQTN2OUG3Oi=>
HepG2/C3A cells	M2PXPWZ2dmO2aX;uJIF{e2G7			M{HyO2FkfGm4YYTpc44hd2ZiaIXtZY4hWFCDUnfhcY1iKGyrZ3Hu[EBjcW6maX7nJIRwdWGrbj3t[YRq[XSnZDD0doFve2O{aYD0bY9v[WxiYXP0bZZqfHliaX6gbJVu[W5iSHXwS\|IwSzODIHPlcIx{KGOxLYTyZY5{\mWldHXkJJdqfGhiZoXz[YQhT2GuND3MRmQh[nliY3;0doFve2[nY4Tpc44h[XO\|YYmsJGVEPTB;MD6wNFM5KM7:TR?=	MVuxO\|QxOzZ6OB?=
HepG2 cells	MoTiSpVv[3Srb36gZZN{[Xl?			NWPIcm1pSWexbnnzeEBi[3Srdnn0fUBifCCSUFHS[4FudWFiZYjwdoV{e2WmIHnuJIh2dWGwIFjldGczKGOnbHzzJIF{e2W\|c3XkJIF{KGmwZIXjeIlwdiCxZjDy[YNmeHSxcjD0doFve2GldHn2ZZRqd25iYomgdoVxd3K2ZYKg[4Vv\SCjc4PhfUBz\WyjdHn2[UB1dyClb370do9tNCCHQ{WwQVAvODVizszN	NX23fFQzOTh4MkW1OVk>
COS1 cells	MlzxSpVv[3Srb36gZZN{[Xl?			MlK4RYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDy[YNwdWKrbnHueEBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIFPPV\|Eh[2WubIOgZ48u\XiycnXzd4lv\yCJQVy0JIF{e2W\|c3XkJIF{KHS{YX7zZ5JqeHSrb37hcEBi[3Srdnn0fUBi\nSncjC0PEBpenNiYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCHQ{WwQVAvODJizszN	NF;VW2gyQTVyN{i2NS=>
HepG2 cells	NX;Zd4VOTnWwY4Tpc44h[XO\|YYm=			MUHB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIGDQRXJo[W2vYTDlfJBz\XO\|ZXSgbY4hUGWyR{KgZ4VtdHNiYomgS2FNPCC2cnHud4FkfGm4YYTpc44h[XO\|YYmsJGVEPTB;MD6yNlMh\|ryP	NVTiSGhMOTh\|OUS5NFc>
CV1 cells	NELOb4JHfW6ldHnvckBie3OjeR?=			M{KwO2Fod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gVHBCWmejbX3hJIxq\2GwZDDibY5lcW6pIHTvcYFqdiCneIDy[ZN{\WRiaX6gZYZzcWOjbjDndoVmdiCvb37r[ZkhS1ZzIHPlcIx{KGOxLYTyZY5{\mWldHXkJJdqfGhiZoXz[YQhT2GuND3ERmQh[nlidILhcpNi[3SrdnH0bY9vKGG\|c3H5MEBGSzVyPUCuNFM{KM7:TR?=	MmKwNVg5OjZ{MEW=
CV1 cells	NGXrUXpHfW6ldHnvckBie3OjeR?=			Mo\GRYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT[WyyaHGgcIlo[W6mIHLpcoRqdmdiZH;tZYlvKGW6cILld5Nm\CCrbjDh[pJq[2GwIHfy[YVvKG2xbnvlfUBEXjFiY3XscJMh[29vdILhcpNn\WO2ZXSge4l1cCCodYPl[EBI[Wx2LVTCSEBjgSC2cnHud4FkfGm4YYTpc44h[XO\|YYmsJGVEPTB;Mz60OkDPxE1?	NEjWPWkyQDh{NkKwOS=>
U2OS cells	M3XvXWZ2dmO2aX;uJIF{e2G7			MWPB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIGDQRXJo[W2vYTDpckBWOk:VIHPlcIx{KGK7IITyZY5{[WO2aY\heIlwdiCjc4PhfUwhTUN3ME2wMlAzKM7:TR?=	MVSxPFMzQTd3MR?=
Hep G2 cells	MVXGeY5kfGmxbjDhd5NigQ>?			MoPhRYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT\2GvbXGgcIlo[W6mIHLpcoRqdmdiZH;tZYlvKGW6cILld5Nm\CCrbjDoeY1idiCKZYCgS\|Ih[2WubIOgZ48ufHKjboPm[YN1\WRid3n0bEBI[Wx2LVTCSEBjgSCudXPp[oVz[XOnIILldI9zfGW{IHflcoUh[XO\|YYmsJGVEPTB;MD6wOEDPxE1?	NWPpb5RKOTlyNUO3O\|Y>
HeLa cells	MVPGeY5kfGmxbjDhd5NigQ>?			MWjB[49vcXO2IHHjeIl3cXS7IHH0JHBRSVKpYX3tZUBtcWejbnSgZolv\GmwZzDkc41icW5iZYjwdoV{e2WmIHnuJIh2dWGwIFjlUIEh[2WubIOgZ48ufHKjboPm[YN1\WRid3n0bEBI[Wx2LVTCSEBie3Onc4Pl[EBieyC2cnHud4NzcXC2aX;uZYwh[WO2aY\heIlwdiCkeTDHZYw1KHKnc4DvcpNmKGWuZX3lcpQu\HKrdnXuJIx2[2moZYLhd4UhemWyb4L0[ZIh\2WwZTDhd5NigSxiRVO1NF0xNjBzNTFOwG0>	Mnv1NVkzPzV7NkO=
COS1 cells	NVTjWlF1TnWwY4Tpc44h[XO\|YYm=			M2e2NGFod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gVHBCWmejbX3hJJJm[2WydH;yJIV5eHKnc4Pl[EBqdiCjZoLpZ4FvKGe{ZXXuJI1wdmuneTDDU3MyKGOnbHzzJINwNXS{YX7z[oVkfGWmIIfpeIgh\nW\|ZXSgfYVie3RiR3HsOE1FSkRiYomgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvODJizszN	MoHjNVk2OzB4OEG=
U2OS cells	NUG1dIJFTnWwY4Tpc44h[XO\|YYm=			NXHqPZZvSWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIGWyU3Mh[2WubIOgZpkhdHWlaX\ldoF{\SC2cnHud4FkfGm4YYTpc44h[XO\|YYmsJGVEPTB;MD6wOUDPxE1?	MknNNVk2PzRyNU[=
HepG2 cells	M1vFTGZ2dmO2aX;uJIF{e2G7			NIrMNo1C\2:waYP0JIFkfGm4aYT5JIF1KEeDTESteIFo\2WmIHj1cYFvKFCSQWLnZY1u[SCuaXfhcoQh[mmwZHnu[{Bld22jaX6g[ZhxemW\|c3XkJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGG\|c3Xzd4VlKGG\|IILlZ4VxfG:{IITyZY5{[WO2aY\heIlwdiCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZktKEWFNUC9NE4xOzlizszN	NVPiTWpIOTl5N{WxOlk>
HepG2 cells	NIO2Z3pHfW6ldHnvckBie3OjeR?=			NXnuOGNWSWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIFjldGczKGOnbHzzJIJ6KEeDTESgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOjJ\|IN88US=>	MkHQNVk4QDN2NES=
COS7 cells	MnTzSpVv[3Srb36gZZN{[Xl?			Ml\iRYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDy[YNwdWKrbnHueEBRWEGUZ3HtcYEzKEyERDDlfJBz\XO\|ZXSgbY4h[W[{aXPhckBoemWnbjDtc45s\XliQ1;TO{Bk\WyuczDjc4V5eHKnc4PpcochT0GONDDifUBtfWOrZnXyZZNmKHKncH;yeIVzKGenbnWgeJJidnOjY4TpeoF1cW:wIHHzd4F6NCCHQ{WwQVAvOSEQvF2=	NEDEN5ozODF\|OEe2Ni=>
COS7 cells	NHHwdlhHfW6ldHnvckBie3OjeR?=			M1PGS2Fod26rc4SgZYN1cX[rdImgZZQhcHWvYX6gdoVkd22kaX7hcpQhWFCDUnfhcY1iOSCOQlSg[ZhxemW\|c3XkJIlvKGGocnnjZY4h\3KnZX6gcY9vc2W7IFPPV\|ch[2WubIOgZ49mgHC{ZYPzbY5oKEeDTESgZpkhdHWlaX\ldoF{\SC{ZYDvdpRmeiCpZX7lJJRz[W6\|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjB\|IN88US=>	MonQNlAyOzh5NkK=
HEK cells	Moi4SpVv[3Srb36gZZN{[Xl?			NIXrdHhC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJGdCVDRvdHHn[4VlKFCSQWLhcJBp[SClaHnt[ZJq[yC{ZXPldJRweiCneIDy[ZN{\WRiaX6gTGVMKGOnbHzzJIJ6KHS{YX7zZYN1cX[jdHnvckBie3OjeTygSWM2OD1zMD61PEDPxE1?	NGjTcIgzODJ7OUKxOC=>
HEK cells	MULGeY5kfGmxbjDhd5NigQ>?			NWLaOnp6SWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBISUx2LYTh[4dm\CCSUFHS[4FudWFiY3jpcYVzcWNicnXj[ZB1d3JiZYjwdoV{e2WmIHnuJGhGUyClZXzsd{BjgSC2cnHud4FkfGm4YYTpc44h[XO\|YYmsJGVEPTB;MD6wN\|Uh\|ryP	MnXQNlAzQTl{MUS=
3T3L1 cells	NXLnbHpzTnWwY4Tpc44h[XO\|YYm=		MoHBO{Bl[Xm\|	M3TZSWlv\HWldHnvckBw\iCjZHnwc4dmdmW\|aYOgbY4hdW:3c3WgN3Q{VDFiY3XscJMh[XO\|ZYPz[YQh[XNiaX7jdoVie2ViaX6gcIlxcWRiYXPjeY12dGG2aX;uJIFnfGW{IEeg[IF6eyCkeTDPbYwhemWmIF:gd5RicW6rbne=	MWeyNFUzPzl4OR?=
CHO-K1 cells	MV7GeY5kfGmxbjDhd5NigQ>?			NXH0[FI6WGG{dHnhcEBi\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZU1NSkRiZYjwdoV{e2WmIHnuJGNJVy2NMTDj[YxteyClbz30doFve2[nY4Tl[EB4cXSqIFfBUFQh[XO\|ZYPz[YQh[XNibIXjbYZmemG\|ZTDhZ5Rqfmm2eTDifUB1emGwc3HjeIl3[XSrb36gZZN{[XluIFXDOVA:OC5zIN88US=>	NG[xXowzODV{N{m2PS=>
HEK293T cells	M{XLcGZ2dmO2aX;uJIF{e2G7	NX\PfpdjOSEQvF2=	MkXQNlQhcHK\|	M33VN3BienSrYXygZYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDQVGFT\2GvbXGtUGJFKGW6cILld5Nm\CCrbjDISWszQTOWIHPlcIx{KGG\|c3Xzd4VlKGG\|IHnu[JVkfGmxbjDv[kBz\WOncITvdkB1emGwc3HjeIl3[XSrb36gZZQhOSC3TTDh[pRmeiB{NDDodpMh[nlibIXjbYZmemG\|ZTDy[ZBwenSncjDn[Y5mKGG\|c3H5	M{LnNlIyODNyMk[z
CV1 cells	M3vOOWZ2dmO2aX;uJIF{e2G7			MXPUdoFve2GldHn2ZZRqd25ib3[gS4FtPC2odYPl[EBpfW2jbjDQVGFT\2GvbXGgSG5CKGKrbnTpcoch\G:vYXnuJIV5eHKnc4Pl[EBqdiCjZoLpZ4FvKGe{ZXXuJI1wdmuneTDDWlEh[2WubIOgZpkhdHWlaX\ldoF{\SC{ZYDvdpRmeiCpZX7lJIF{e2G7LDDFR\|UxRTBwMTFOwG0>	NFrQOGwzOTFzMke4OC=>
HEK293 cells	NFzVVJVHfW6ldHnvckBie3OjeR?=		MV6xOkB1dyB{MDDodpM>	NVHMOGZoXHKjboPhZ5RqfmG2aX;uJI9nKEejbESt[pV{\WRiaIXtZY4hWFCDUnfhcY1iKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMh[W[2ZYKgNVYhfG9iMkCgbJJ{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlA1OyEQvF2=	NHfwUJQzOTF{OE[wNC=>
HepG2 cells	MX3GeY5kfGmxbjDhd5NigQ>?	MYCxNEB2dW:uL1y=	NELlSVQzPCCqcoO=	Ml;WTY5kemWjc3WgbY4h\2y3Y3;z[UBkd26\|dX3weIlwdiCrbjDoeY1idiCKZYDHNkBk\WyuczDheEAyOCC3bX;sM2wh[W[2ZYKgNlQhcHK\|IILlcIF1cX[nIITvJINwdnS{b3y=	NWHaVod7OjF{NU[3OFg>
3T3L1 cell	NUjlc2lGTnWwY4Tpc44h[XO\|YYm=	MmH2NUB2VQ>?		Moq4TY5lfWO2aX;uJI9nKG2xdYPlJFNVO0xzIHPlcIwh\GmoZnXy[Y51cWG2aX;uJIF{e2W\|c3XkJIF{KGmwY4LlZZNmKGmwIHHjZ5VufWyjdHnvckBw\iCrboTyZYNmdGy3bHHyJIxqeGmmIHTyc5Bt\XRiYYSgNUB2VSCkeTDPbYwhemWmIF:gd5RicW6rbne=	MnX4NlE1ODFzMUi=
CV1 cells	MljqSpVv[3Srb36gZZN{[Xl?		NWDKUIY1PDBiaB?=	NFHjeItC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZU1NSkRiZYjwdoV{e2WmIHnuJGNXOSClZXzsd{Bkdy22cnHud4Zm[3SnZDD3bZRpKEejbESgZYZ1\XJiNECgbJJ{KGK7IHz1Z4ln\XKjc3WgZoF{\WRidILhcpNi[3SrdnH0bY9vKGG\|c3H5MEBGSzVyPUCuNUDPxE1?	MX[yNVUyPTB4Mx?=
HepG2 cells	MoTnSpVv[3Srb36gZZN{[Xl?			M2L6XWFod26rc4SgZYN1cX[rdImgZZQhWFCDUnfhcY1iKHKnY3XweI9zKGW6cILld5Nm\CCrbjDoeY1idiCKZYDHNkBk\WyuczDifUBRWFKHLXz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlAyKM7:TR?=	NH\hV3kzOTR6MkS0Oi=>
HepG2 cells	NELmS3lHfW6ldHnvckBie3OjeR?=			Mn7sWJJidnOjY4TpeoF1cW:wIH;mJIh2dWGwIGDQRXJo[W2vYTDlfJBz\XO\|ZXSgbY4hcHWvYX6gTIVxTzJiY3XscJMh[29vdILhcpNn\WO2ZXSge4l1cCCSUGLFN{1VUy2OdXOgZpkhdHWlaX\ldoF{\SC{ZYDvdpRmeiCpZX7lJIF{e2G7LDDFR\|UxRTBwMEWg{txO	MWOyNVQ2ODR4OB?=
COS7 cells	M2DofmZ2dmO2aX;uJIF{e2G7			M2fNe21w\HWuYYTpc44hd2ZiaIXtZY4hWFCDUnfhcY1iNUyERDDlfJBz\XO\|ZXSgbY4h[W[{aXPhckBoemWnbjDtc45s\XliQ1;TO{Bk\WyuczDjc{11emGwc3\lZ5Rm\CC5aYToJGdidDRiYYPz[ZN{\WRiYYOgZYN1cX[jdHnvckBw\iC2cnHud4FkfGm4YYTpc44h[WO2aY\peJkh[nlibIXjbYZmemG\|ZTDhd5NigSxiRVO1NF0xNjB2MzFOwG0>	NWDyZnhrOjF6N{OwO\|A>
COS-1 cells	NVryS\|hYTnWwY4Tpc44h[XO\|YYm=		NYnXR\|ZYOjRiaILz	MWrB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIGDQRXJo[W2vYTDsbYdidmRiYnnu[Ilv\yCmb33hbY4h\XiycnXzd4VlKGmwIFPPV{0yKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmVvYnHz[YQhdHWvaX7vcYV1emmlIHHuZYx6e2m\|LDDFR\|UxRTBwMES4JO69VQ>?	NG\INmozOjB3MUC1OC=>
COS1 cells	NVnmZohqTnWwY4Tpc44h[XO\|YYm=		M4TtN\|I1KGi{cx?=	MXXUdoFve2GldHn2ZZRqd25ib3[gbJVu[W5iZoXscEBt\W6pdHigVHBCWmejbX3hJIV5eHKnc4Pl[EBqdiCFT2OxJINmdGy\|IHPvMZRz[W6\|ZnXjeIVlKHerdHigVnhT[WyyaHGgZYZ1\XJiMkSgbJJ{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlEzKM7:TR?=	M3fYNVIzOTl5M{m2
MG-63 cells	MkLNSpVv[3Srb36gZZN{[Xl?			NVPYNJVuSWexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBRWEGUZ3HtcYEh\XiycnXzd4VlKGmwIF3HMVY{KGOnbHzzJIJ6KHKncH;yeIVzKGenbnWtZoF{\WRidILhcpNi[3SrdnH0bY9vKGG\|c3H5MEBGSzVyPUCuNFEyKM7:TR?=	M4jJclIzOjJ3NkSx
COS1 cells	M2DLVmZ2dmO2aX;uJIF{e2G7			MW\CbY5lcW6pIHHm[olvcXS7IITvJIh2dWGwIIfpcIQhfHmyZTDQVGFT\2GvbXGgUGJFKGW6cILld5Nm\CCrbjDDU3MyKGOnbHzzJINwNWW6cILld5NqdmdiR1HMOEBjgSC\|Y3nueIltdGG2aX;uJJBzd3irbXn0fUBie3OjeR?=	MXuyNlA4ODZyNB?=
MG-63 cells	MUjGeY5kfGmxbjDhd5NigQ>?		M1e5dVI1KGi{cx?=	NV7OUIN3VW:mdXzheIlwdiCxZjDmeYxtNWynbnf0bEBpfW2jbjDwV2c2NW[3c3XkJHBRSVKpYX3tZUBmgHC{ZYPz[YQhcW5iTVetOlMh[2WubIOgZ48u\XiycnXzd4lv\yCyR2[tVFIuWFCURTDh[pRmeiB{NDDodpMh[nlibIXjbYZmemG\|ZTDy[ZBwenSncjDn[Y5mKGKjc3XkJJRz[W6\|YXP0bZZifGmxbjDhd5NigSxiRVO1NF0xNjBzMTFOwG0>	MoHtNlI4Ojd2NEi=
Ac2F cells	MkjiSpVv[3Srb36gZZN{[Xl?	Mle0NE4yKHSxIEGwJO69VQ>?	MnfDOkBpenN?	MonHRYdwdmm\|dDDhZ5Rqfmm2eTDheEBRWEGUZ3HtcYEhcW5icnH0JGFkOkZiY3XscJMh[XO\|ZYPz[YQh[XNibIXjbYZmemG\|ZTDhZ5Rqfmm2eTDheEAxNjFidH:gNVAhfU1iYX\0[ZIhPiCqcoOgZpkhemWyb4L0[ZIh\2WwZTDhd5NigQ>?	NH[3Vo0zOjhzOUG5NC=>
293H DA cells	NFHRfnlHfW6ldHnvckBie3OjeR?=		MoLLNVYhcA>?	NXP5[pFFSWexbnnzeEBi[3Srdnn0fUBifCCSUFHS[4FudWFiTFLEJIlvKGi3bXHuJFI6O0hiRFGgZ4VtdHNiYX\0[ZIhOTZiaILzJIJ6KFSULV\SSXQh[WO2aY\heIlwdiC{ZYDvdpRmeiCjc4PhfUwhTUN3ME2wMlAxOjRizszN	MnnINlI2QDJ7N{O=
3T3L1 cells	NIX5OWlHfW6ldHnvckBie3OjeR?=	NIjQNWoyOCC3TR?=		M3j6Nmlv[3KnYYPlJIlvKGGmaYDvcoVkfGmwIH3SUmEhdGW4ZXzzJIlvKFSQRnHsdIhiNWmwZIXj[YQhdW:3c3WgN3Q{VDFiY3XscJMheHKndILlZZRm\CCjdDCxNEB2VSCkZX\vdoUhXE6ILXHsdIhiKGOqYXzs[Y5o\SC{ZXzheIl3\SC2bzDjc451em:u	MYKyNVg2OTB6OR?=
HepG2 cells	NFXsR3ZHfW6ldHnvckBie3OjeR?=	NYfXW29DOTBidV2=	NF\0fXgzPCCq	NWj6[GpYWmWmdXP0bY9vKG:oIHfseYNwe2ViY3;ud5VueHSrb36gbY4hcW6\|dXzpck1z\XOrc4ThcpQhcHWvYX6gTIVxTzJiY3XscJMh[XRiMUCgeW0h[W[2ZYKgNlQhcHK\|IHL5JIdtfWOxc3Wgc5hq\GG\|ZTDt[ZRpd2RiaX6gdJJme2WwY3Wgc4YhOjJwMjDtUUBw\iCpbIXjc5Nm	Ml74NlMxOjV{NES=
HepG2 cells	NXzQU3g4TnWwY4Tpc44h[XO\|YYm=	NEHjS3UyOCC3TR?=	MUiyOEBp	NFXRSYZT\WS3Y4Tpc44hd2ZiZ3z1Z49{\SClb37zeY1xfGmxbjDpckBqdnO3bHnuMZJme2m\|dHHueEBpfW2jbjDI[ZBIOiClZXzsd{BifCBzMDD1UUBi\nSncjCyOEBpenNiYomg[4x2[2:\|ZTDvfIll[XOnIH3leIhw\CCrbjDwdoV{\W6lZTDv[kAxNjFidV2gc4YhcW6\|dXzpci=>	NEPoWoIzOzB{NUK0OC=>
THP1 cells	M4CzUmZ2dmO2aX;uJIF{e2G7	MXyxNFAhfU1?	MnzVN{BpenN?	MVLUdoFve2GldHn2ZZRqd25ib3[gVHBCWmejbX3hJIlvKGi3bXHuJHRJWDFiY3XscJMh[XO\|ZYPz[YQh[XNiZHXjdoVie2ViaX6gUHBUNWmwZIXj[YQhVUOSMTDtVm5CKGW6cILld5Nqd25iYYSgNVAxKHWPIIDy[Ylv[3WkYYTl[EBnd3JiMzDodpMheHKrb4KgeI8hVFCVIHPoZYxt\W6pZTDt[YF{fXKnZDDh[pRmeiBzODDodpMh[nliUmStVGNTKGGwYXz5d4l{KHKnbHH0bZZmKHSxIIXueJJm[XSnZDDjc451em:u	NHv1Zm4zOjl\|NEWzOy=>
THP1 cells	NVHDSHI{TnWwY4Tpc44h[XO\|YYm=	NXXUdWMyOTByIIXN	MYezJIhzew>?	NIXCR3JVemGwc3HjeIl3[XSrb36gc4YhWFCDUnfhcY1iKGmwIHj1cYFvKFSKUEGgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4hVFCVLXnu[JVk\WRiSVy2JI1TVkFiZYjwdoV{e2mxbjDheEAyODBidV2gdJJmcW6ldXLheIVlKG[xcjCzJIhzeyCycnnvdkB1dyCOUGOgZ4hidGynbnflJI1m[XO3cnXkJIFnfGW{IEG4JIhzeyCkeTDSWE1RS1JiYX7hcJl{cXNicnXsZZRqfmVidH:geY51emWjdHXkJINwdnS{b3y=	MXGyNlk{PDV\|Nx?=
HepG2 cells	MnnLSpVv[3Srb36gZZN{[Xl?			M2[3XXRz[W6\|YXP0bZZifGmxbjDv[kBISUx2LX\1d4VlKFCSQWLnZY1u[SCuaXfhcoQh[mmwZHnu[{Bld22jaX6geJJidnOoZXP0[YQhcW5iaIXtZY4hUGWyR{KgZ4VtdHNiYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCHQ{WwQVAvOSEQvF2=	MlL1NlI6OzR3M{e=
HepG2 cells	NV\vVGlKTnWwY4Tpc44h[XO\|YYm=		MV2yNEBp	MU\B[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIFfBUFQu\nW\|ZXSgVHBCWmejbX3hJIxq\2GwZDDibY5lcW6pIHTvcYFqdiCneIDy[ZN{\WRiaX6gTIVxTzJiY3XscJMh[W[2ZYKgNlAhcHK\|IHL5JIx2[2moZYLhd4UhemWyb4L0[ZIh\2WwZTD0doFve2GldHn2ZZRqd25iYYPzZZktKEWFNUC9NE4xOiEQvF2=	NE\LXHgzOjB6MUmzNi=>
BL21 DE3 cells	NGfMNm9HfW6ldHnvckBie3OjeR?=			NGflWmtFcXOybHHj[Y1mdnRib3[gX\|NJZXKxc3nncIl1[XqxbnWg[pJwdSCQLYTldo1qdmGuIFjpd{11[WepZXSgbJVu[W5iUGDBVodidW2jIHzp[4Fv\CCkaX7kbY5oKGSxbXHpckBmgHC{ZYPz[YQhcW5iRYPjbIVzcWOqaXGgZ49tcSCETEKxJGRGOyClZXzsd{BjgSC\|Y3nueIltdGG2aX;uJJBzd3irbXn0fUBie3OjeTygT4k:OC5yN{Sg{txO	NFzQ[nMzOjB6MUmzNi=>
human L02 cells	NF;pPVhHfW6ldHnvckBie3OjeR?=			MULB[49vcXO2IHHjeIl3cXS7IHH0JHBRSVKpYX3tZU1NSkRiZYjwdoV{e2WmIHnuJIh2dWGwIFywNkBk\WyuczDjc{1mgHC{ZYPzbY5oKHCJTEOtV3Y1OC2JQVy0JIFnfGW{IEK0JIhzeyCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYnHz[YQhfHKjboPhZ5RqfmG2aX;uJIF{e2G7LDDFR\|UxRTBwOTFOwG0>	MXyyN\|E5PjNyNx?=
HepG2 cells	NWPuemNTTnWwY4Tpc44h[XO\|YYm=		NWS3[m52OjBiaB?=	NXLsTZR{XHKjboPhZ5RqfmG2aX;uJI9nKEeDTESt[pV{\WRiaIXtZY4hWFCDUnfhcY1iKGyrZ3Hu[EBjcW6maX7nJIRwdWGrbjDlfJBz\XO\|ZXSgbY4hUGWyR{KgZ4VtdHNiYX\0[ZIhOjBiaILzJIJ6KGy3Y3nm[ZJie2VicnXwc5J1\XJiZ3Xu[UBie3OjeTygSWM2OD1yLkCzPUDPxE1?	NGLhRmgzOzF5MUC0OS=>
HEK293 cells	M3G0NWZ2dmO2aX;uJIF{e2G7	NGmwbokyOCEQvF2=		NULF[pFyXHKjboPhZ5RqfmG2aX;uJI9nKFCSQWLnZY1u[SBqdX7rco94diCxcnnnbY4qKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMh[29vdILhcpNn\WO2ZXSge4l1cCCDUEKtVHBTTSCjdDCxNEB2VSCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZk>	M1S5T\|I{Ojd\|NUG5
HEK293 cells	M4TXemZ2dmO2aX;uJIF{e2G7			NF7sfVZC\2:waYP0JIF1KGi3bXHuJHBRSVKpYX3tZUBNSkRiZYjwdoV{e2WmIHnuJIh2dWGwIFjFT\|I6OyClZXzsd{Bkd3S{YX7z[oVkfGWmIIfpeIghT0GOND3MeYMh[XO\|ZYPz[YQh[XNidILhcpNkemmydHnvcoFtKGGldHn2ZZRqd25iYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCHQ{WwQVAvODB2IN88US=>	M{jQe\|I{Ojh4N{i3
HEK293 cells	MnnUSpVv[3Srb36gZZN{[Xl?		MnzxNlQhcA>?	M4f5OHRz[W6\|YXP0bZZifGmxbjDv[kBISUx2IFTCSE1nfXOnZDDoeY1idiCSUFHS[4FudWFvTFLEJIV5eHKnc4Pl[EBqdiCKRVuyPVMh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlEh\|ryP	NIHo[XUzOzJ7NEizNC=>
HEK293 cells	MVPGeY5kfGmxbjDhd5NigQ>?		MoG2OFghcHK\|	NHjWO5lC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZUBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzJINwfHKjboPm[YN1\WRid3n0bEBRWFKHeEStWGsudHWlIHHzd4V{e2WmIHHzJIFkfGm4YYTpc44hd2ZibIXjbYZmemG\|ZTDhZ5Rqfmm2eTDt[YF{fXKnZDDh[pRmeiB2ODDodpMh[nlidILhcpNi[3SrdnH0bY9vKGG\|c3H5MEBGSzVyPUSzMlcyKM7:TR?=	NIflPGczOzJ4NUi0OC=>
HepG2 cells	MlTRSpVv[3Srb36gZZN{[Xl?			NX:0UY9DSWexbnnzeEBi[3Srdnn0fUBifCCJQVy0MYZ2e2WmIGDQRXJo[W2vYTCoeY5sdm:5bjDvdolocW5rIHX4dJJme3OnZDDpckBpfW2jbjDI[ZBIOiClZXzsd{BjgSC2cnHud4FkfGm4YYTpc44h[XO\|YYmsJGVEPTB;MD6wNUDPxE1?	MkflNlM2ODJ{MUK=
HepG2 cells	NUL6VJA3TnWwY4Tpc44h[XO\|YYm=			MVfB[49vcXO2IHHjeIl3cXS7IHH0JGdCVDRvZoXz[YQhWFCDUnfhcY1iKE12NkPBJI12fGGwdDCoeY5sdm:5bjDvdolocW5rIHX4dJJme3OnZDDpckBpfW2jbjDI[ZBIOiClZXzsd{BjgSC2cnHud4FkfGm4YYTpc44h[XO\|YYmsJGVEPTB;MD6wNFIh\|ryP	NHjsVIgzOzVyMkKxNi=>
L6 cells	MWfGeY5kfGmxbjDhd5NigQ>?		NUHESYF[OjRiaILz	NYHicZhFUW6mdXP0bY9vKG:oIHfseYNwe2VidYD0ZYtmKGmwIILheEBNPiClZXzsd{BxfWy\|ZXSge4l1cCCFMUSt[IVwgHliZ3z1Z49{\SCjZoTldkAzPCCqcoOgbY4heHKnc3XuZ4Uhd2ZiaX7zeYxqdixiRVO1NF01NjR7IN88US=>	NWHZc5VsOjN7OUK4OlI>
L6 cells	NXrOfnhITnWwY4Tpc44h[XO\|YYm=		NE\3T4wyPiCqcoO=	NGHYWXJKdmO{ZXHz[UBqdiB{LWuzTH0u\GWxeInncJVkd3OnIIXweIFs\SCrbjDyZZQhVDZiY3XscJMh[W[2ZYKgNVYhcHK\|IHL5JJNkcW62aXzsZZRqd25iY3;1cpRqdmdiYX7hcJl{cXNuIFXDOVA:PC56IN88US=>	NXHlXYtwOjR6MUO3N\|g>
DU145 cells	MUfDfZRwfG:6aXPpeJkh[XO\|YYm=		MX20PEBpenN?	MmjoR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[XO\|ZYPz[YQh[XNiZ4Lve5RpKGmwaHnibZRqd25iYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiRVO1NF0yPiEQvF2=	NIrweYEzPDl7NkG0Ny=>
PC3 cells	MoPnR5l1d3SxeHnjbZR6KGG\|c3H5		NH;EXFA1QCCqcoO=	NVrrfnBOS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN\|IHPlcIx{KGG\|c3Xzd4VlKGG\|IHfyc5d1cCCrbnjpZol1cW:wIHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFXDOVA:OjBwMzFOwG0>	NWHrbWtOOjR7OU[xOFM>
MDA-MB-231 cells	NIXudlZIem:5dHigbY5pcWKrdHnvckBie3OjeR?=		NUPUcIo{OjRiaILz	MVXHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDNSGEuVUJvMkOxJINmdGy\|IHHmeIVzKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFXDOVA:PS5{MzFOwG0>	NYry[\|BpOjV{N{iyN\|Y>
HEK293 cells	NXj0UXZETnWwY4Tpc44h[XO\|YYm=			NF6zNZhC\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHBRSVKpYX3tZUBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzJIJ6KGy3Y3nm[ZJie2VicnXwc5J1\XJiZ3Xu[UBie3OjeTygSWM2OD1yLkCxJO69VQ>?	MWGyOVMxPTZ6OB?=
HepG2 cells	NFrhXZpHfW6ldHnvckBie3OjeR?=		NYjETFg4OjBiaILz	NIjGV5lVemGwc3HjeIl3[XSrb36gc4YhWFCDUjD0doFve2[nY4Tl[EBqdiCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkAzOCCqcoOgZpkhWFCDUj3seYNq\mW{YYPlJIF{e2G7LDDFR\|UxRTFwNjFOwG0>	MWmyOVQ{PzNyNB?=
HEK293 cells	Ml3sSpVv[3Srb36gZZN{[Xl?		M2S5dVI1KGi{cx?=	M2D3PHRz[W6\|YXP0bZZifGmxbjDv[kBRWEGUZ3HtcYEhMHWwa37ve44hd3KrZ3nuLUBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzJIlv[3WkYYTl[EBnd3JiMkSgbJJ{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfS=>	MmDCNlU1PDJ\|MkK=
HepG2 cells	MYXGeY5kfGmxbjDhd5NigQ>?			MmHIRYdwdmm\|dDDhZ5Rqfmm2eTDheEBpfW2jbjDHRWw1NVCSQWLnZY1u[SCuaXfhcoQh[mmwZHnu[{Bld22jaX6g[ZhxemW\|c3XkJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlA{QSEQvF2=	MnjhNlU1PjJ{OEG=
HEK293 cells	M3fJN2Z2dmO2aX;uJIF{e2G7		M2LBbFI1KGi{cx?=	M4LUcmFod26rc4SgZYN1cX[rdImgZZQhdW:3c3WgVHBCWmejbX3hJIV5eHKnc4Pl[EBqdiCKRVuyPVMh[2WubIOgZ48u\XiycnXzd4lv\yC5aYToJGdidDRicnXwc5J1\XJidnXjeI9zKGGodHXyJFI1KGi{czDifUBlfWGuLXz1Z4ln\XKjc3WgdoVxd3K2ZYKgZZN{[XluIFXDOVA:OC5yMzFOwG0>	NV3WT4NEOjR7NUW4PFk>
HepG2 cells	MXrGeY5kfGmxbjDhd5NigQ>?		NYjheGh7OjBiaILz	MWfB[49vcXO2IHHjeIl3cXS7IHH0JGdCVDRvRF7BJIJqdmSrbneg[I9u[WmwIH\1d4VlKGi3bXHuJHBRSVKpYX3tZUBtcWejbnSgZolv\GmwZzDkc41icW5iZYjwdoV{e2WmIHnuJIh2dWGwIFjldGczKGOnbHzzJIF{e2W\|c3XkJIF{KHKnY3XweI9zKHS{YX7zZYN1cX[jdHnvckBqdmO3YnH0[YQh\m:{IEKwJIhzeyCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZktKEWFNUC9NE4xPCEQvF2=	MnT5NlU1QTdzM{K=
HepaR cells	NIDtRo1HfW6ldHnvckBie3OjeR?=		Mn\kNUBl[Xl?	M4L4W2Fod26rc4SgZYN1cX[rdImgZZQhWFCDUnfhcY1iKGmwIHj1cYFvKEincHHSJINmdGy\|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKEiPR1PTNkBo\W6nIHX4dJJme3Orb36gZZQhOSC3TTDpcoN2[mG2ZXSg[o9zKDFiZHH5JIJ6KHG3YX70bZRifGm4ZTDQR3IhdWW2aH;kJJJmdGG2aY\lJJRwKHWwdILlZZRm\CClb370do9t	M1uzTVI2PDl5MUOy
HepaR cells	NHjOfIRHfW6ldHnvckBie3OjeR?=	NHvIXWgyKHWP	MV6xJIRigQ>?	NFPLcVVC\2:waYP0JIFkfGm4aYT5JIF1KFCSQWLnZY1u[SCrbjDoeY1idiCKZYDhVkBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCDTlfQWGw1KGenbnWg[ZhxemW\|c3nvckBifCBzIIXNJIlv[3WkYYTl[EBnd3JiMTDkZZkh[nlicYXhcpRqfGG2aY\lJHBEWiCvZYToc4QhemWuYYTpeoUhfG9idX70doVifGWmIHPvcpRzd2x?	Ml;VNlU1QTdzM{K=
HepaR cells	MUXGeY5kfGmxbjDhd5NigQ>?	M4X1N\|EhfU1?	NYO2S3poOSCmYYm=	M2DSTmFod26rc4SgZYN1cX[rdImgZZQhWFCDUnfhcY1iKGmwIHj1cYFvKEincHHSJINmdGy\|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKE[DQmCxJIdmdmViZYjwdoV{e2mxbjDheEAyKHWPIHnuZ5Vj[XSnZDDmc5IhOSCmYYmgZpkheXWjboTpeIF1cX[nIGDDVkBu\XSqb3SgdoVt[XSrdnWgeI8hfW62cnXheIVlKGOxboTyc4w>	MkDUNlU1QTdzM{K=
HEK293 cells	M1jvemZ2dmO2aX;uJIF{e2G7	NH;XUogyOCEQvF2=	M4O3fFI1KGi{cx?=	NE[2b2lVemGwc3HjeIl3[XSrb36gc4YhWFCDUj3nZY1u[SBqdX7rco94diCxcnnnbY4qKGW6cILld5Nm\CCrbjDISWszQTNiY3XscJMh[XRiMUCgeW0h[W[2ZYKgNlQhcHK\|IHL5JIx2[2moZYLhd4UhemWyb4L0[ZIh\2WwZTDhd5NigQ>?	MXyyOFg6ODB7MB?=
C2C12 cells	NVvjNZJTTnWwY4Tpc44h[XO\|YYm=	NWPjT2U{OzBizszN	M{e5TFIhcA>?	MWTJcoR2[3Srb36gc4YhOi2mZX;4fU1cO0ifLXfseYNwe2VidYD0ZYtmKGmwIH3veZNmKEN{Q{GyJINmdGy\|IHH0JFMxKHWPIHHmeIVzKDJiaILzJIJ6KGyrcYXp[EB{[2mwdHnscIF1cW:wIHPveY51cW6pIHHuZYx6e2m\|	NUi0O2JzOjV6M{W1N\|c>
MCF7 cells	NFewSWZHfW6ldHnvckBie3OjeR?=		NF7GUnoyPiCq	MVXB[49vcXO2IHHjeIl3cXS7IHH0JIh2dWGwIGDQRXJo[W2vYTD0doFve2[nY4Tl[EBqdiCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFE3KGi{czDifUBtfWOrZnXyZZNmKHKncH;yeIVzKGenbnWgZZN{[XluIFXDOVA:OC5yOEeg{txO	MYiyOlIzPjR7MB?=
HEK293 cells	NVHaR402TnWwY4Tpc44h[XO\|YYm=	MnzGNVAh\|ryP	NF;KT5MzPCCq	MkH0RYdwdmm\|dDDhZ5Rqfmm2eTDheEBRWEGUZ3HtcYEhMHWwa37ve44hd3KrZ3nuLUBmgHC{ZYPz[YQhcW5iSFXLNlk{KGOnbHzzJIF{e2W\|c3XkJIF{KHKnY3XweI9zKHS{YX7zZYN1cX[jdHnvckBifCBzMDD1UUBqdmO3YnH0[YQh\m:{IEK0JIhzeyCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZk>	MXGyOlM5PDJ6Nh?=

... Click to View More Cell Line Experimental Data

Protocol

References

Solubility (25°C)

In vitro	DMSO	35 mg/mL (198.67 mM)
	Ethanol	35 mg/mL (198.67 mM)
	Water	Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download 4-Methylumbelliferone (4-MU) SDF

Molecular Weight	176.17
Formula	C₁₀H₈O₃
CAS No.	90-33-5
Storage	3 years-20°C powder 2 years-80°C in solvent
Synonyms	N/A
Smiles	CC1=CC(=O)OC2=C1C=CC(=C2)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage

mg/kg

Average weight of animals

Dosing volume per animal

Number of animals

Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)

% DMSO+ % + % Tween 80+ % ddH₂O

Calculate Reset

Calculation results:

Working concentration： mg/ml；

Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH₂O，mix and clarify.

Note：1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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4-Methylumbelliferone (4-MU)