BI 2536

Name: BI 2536
Brand: Selleck Chemicals
SKU: S1109
Rating: 5 (209 reviews)

For research use only.

Catalog No.S1109

209 publications

CAS No. 755038-02-9

BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.

Selleck's BI 2536 has been cited by 209 publications

Cancer Cell, 2020, 37(3):340-353

PubMed: 32109375 ( click the link to review the publication )

Science, 2019, 364(6447)

PubMed: 31249032 ( click the link to review the publication )

Cancer Cell, 2019, 36(2):179-193

PubMed: 31378681 ( click the link to review the publication )

Cell, 2019, 36(2):179-193

PubMed: 28162770 ( click the link to review the publication )

Nature, 2017, 548(7668):466-470

PubMed: 28759889 ( click the link to review the publication )

Science, 2015, 13;347(6227):aaa2630.

PubMed: 25636800 ( click the link to review the publication )

Cancer Discov, 2014, 4(11):1281-9

PubMed: 25107667 ( click the link to review the publication )

Cell, 2011, 11;147(4):853-67.

PubMed: 22078882 ( click the link to review the publication )

Cancer Cell, 2010, 18(6):641-54

PubMed: 21156286 ( click the link to review the publication )

Mol Cell, 2020, S1097-2765(20)30774-7

PubMed: 33248027 ( click the link to review the publication )

Mol Cell, 2020, 10.1016/j.molcel.2020.01.023

PubMed: 32035037 ( click the link to review the publication )

Nat Commun, 2020, 29;11(1):2086

PubMed: 32350249 ( click the link to review the publication )

Nat Commun, 2020, 14;11(1):1819

PubMed: 32286328 ( click the link to review the publication )

Autophagy, 2020, 1-17

PubMed: 33315519 ( click the link to review the publication )

J Cell Biol, 2020, 219(11)e201910148

PubMed: 33053167 ( click the link to review the publication )

J Cell Biol, 2020, 1;219(6):e201910019

PubMed: 32271878 ( click the link to review the publication )

Cell Rep, 2020, 32(9):108080

PubMed: 32877684 ( click the link to review the publication )

Cell Rep, 2020, 17;30(11):3605-3615.e5

PubMed: 32187533 ( click the link to review the publication )

Cell Death Differ, 2020, 19

PubMed: 32203171 ( click the link to review the publication )

Oncogene, 2020, 39(15):3145-3162

PubMed: 32060423 ( click the link to review the publication )

Cancers (Basel), 2020, 12(9)E2498

PubMed: 32899210 ( click the link to review the publication )

Cells, 2020, 9(9)E2126

PubMed: 32961751 ( click the link to review the publication )

Cell Chem Biol, 2020, 27(3):350-362

PubMed: 32017920 ( click the link to review the publication )

Curr Biol, 2020, 30(22):4519-4527.e3

PubMed: 32916112 ( click the link to review the publication )
ACS Chem Biol, 2020, 20;15(3):669-674

PubMed: 32004428 ( click the link to review the publication )

J Cell Sci, 2020, 2;jcs.244442

PubMed: 32487663 ( click the link to review the publication )

Biochem Biophys Res Commun, 2020, 521(4):833-839

PubMed: 31708096 ( click the link to review the publication )

DNA Cell Biol, 2020, 10.1089/dna.2019.5002

PubMed: 32182129 ( click the link to review the publication )

Antivir Ther, 2020, 25(3):151-162

PubMed: 32496211 ( click the link to review the publication )

Front Vet Sci, 2020, 7:611270

PubMed: 33409299 ( click the link to review the publication )

Cell Death Differ, 2020, 10.1038

PubMed: 32015503 ( click the link to review the publication )

Sci Rep, 2020, 10(1):12327

PubMed: 32704044 ( click the link to review the publication )

Cells, 2020, 9(1)

PubMed: 31947732 ( click the link to review the publication )

J Cancer, 2020, 11(11):3274-3287

PubMed: 32231733 ( click the link to review the publication )

Neuroreport, 2020, 31(11):787-797

PubMed: 32568772 ( click the link to review the publication )

Cancers (Basel), 2020, 12(7):1824

PubMed: 32645997 ( click the link to review the publication )

Cell Res, 2019, 29(7):562-578

PubMed: 31201382 ( click the link to review the publication )

Mol Cell, 2019, 73(5):915-929

PubMed: 30849395 ( click the link to review the publication )

Nat Commun, 2019, 10(1):3779

PubMed: 31439829 ( click the link to review the publication )

Nat Commun, 2019, 10(1):1473

PubMed: 30931927 ( click the link to review the publication )

Nat Commun, 2019, 10(1):993

PubMed: 30824690 ( click the link to review the publication )

Sci Adv, 2019, 5(8):eaav0318

PubMed: 31803841 ( click the link to review the publication )

Cell Syst, 2019, 8(2):163-167

PubMed: 30797774 ( click the link to review the publication )

Cell Syst, 2019, 9(1):74-92.e8

PubMed: 31302152 ( click the link to review the publication )

J Cell Biol, 2019, 218(4):1250-1264

PubMed: 30728176 ( click the link to review the publication )

EBioMedicine, 2019, 41:244-255

PubMed: 30876762 ( click the link to review the publication )

Cell Death Dis, 2019, 10(6):385

PubMed: 31097686 ( click the link to review the publication )

Ther Adv Med Oncol, 2019, 11:1758835919846375

PubMed: 31156720 ( click the link to review the publication )
J Mol Cell Biol, 2019, 10.1093/jmcb/mjz051

PubMed: 31174204 ( click the link to review the publication )

Curr Biol, 2019, 29(7):1232-1242.e5

PubMed: 30905608 ( click the link to review the publication )

Mol Cancer Ther, 2019, 18(9):1615-1627

PubMed: 31227645 ( click the link to review the publication )

FEBS J, 2019, 286(5):963-974

PubMed: 30600590 ( click the link to review the publication )

Mol Cancer Res, 2019, doi: 10

PubMed: 31604847 ( click the link to review the publication )

Mol Biol Cell, 2019, 30(13):1598-1609

PubMed: 31042116 ( click the link to review the publication )

Lab Invest, 2019, 99(9):1275-1286

PubMed: 30996295 ( click the link to review the publication )

Sci Rep, 2019,

PubMed: 31511529 ( click the link to review the publication )

Cell Div, 2019, 14:4

PubMed: 31110557 ( click the link to review the publication )

J Biol Chem, 2019, 294(22):8760-8772

PubMed: 31010829 ( click the link to review the publication )

Front Genet, 2019, 10:411

PubMed: 31130988 ( click the link to review the publication )

Open Biol, 2019, 9(8):190136

PubMed: 31455158 ( click the link to review the publication )

Mol Reprod Dev, 2019, 86(8):972-983

PubMed: 31136049 ( click the link to review the publication )

Planta Med, 2019, 85(3):217-224

PubMed: 30199903 ( click the link to review the publication )

Elife, 2019, 8e47097

PubMed: 31393265 ( click the link to review the publication )

Mol Cell, 2018, 71(1):117-128

PubMed: 30008317 ( click the link to review the publication )

EMBO Mol Med, 2018, 10(9)

PubMed: 30108112 ( click the link to review the publication )

Theranostics, 2018, 8(10):2884-2895

PubMed: 29774081 ( click the link to review the publication )

Cancer Res, 2018, 78(2):572-583

PubMed: 29180474 ( click the link to review the publication )

Elife, 2018, 7:e36739

PubMed: 29897330 ( click the link to review the publication )

Sci Signal, 2018, 11(549)

PubMed: 30254057 ( click the link to review the publication )

Sci Signal, 2018, 11(530)

PubMed: 29764992 ( click the link to review the publication )

Pigment Cell Melanoma Res, 2018, 31(2):253-266

PubMed: 28972303 ( click the link to review the publication )

Mol Cancer Ther, 2018, 17(12):2551-2563

PubMed: 30217967 ( click the link to review the publication )
Mol Cancer Ther, 2018, 17(7):1554-1565

PubMed: 29716963 ( click the link to review the publication )

Mol Cell Proteomics, 2018, 17(12):2434-2447

PubMed: 30217950 ( click the link to review the publication )

J Cell Mol Med, 2018, 22(11):5300-5310

PubMed: 30133120 ( click the link to review the publication )

Hum Gene Ther, 2018, 29(8):886-901

PubMed: 29641320 ( click the link to review the publication )

Sci Rep, 2018, 8(1):3521

PubMed: 29476067 ( click the link to review the publication )

Cell Signal, 2018, 52:137-146

PubMed: 30223016 ( click the link to review the publication )

Cancer Med, 2018, 7(11):5589-5603

PubMed: 30221846 ( click the link to review the publication )

Transl Oncol, 2018, 11(4):852-863

PubMed: 29753186 ( click the link to review the publication )

PLoS One, 2018, 13(5):e0197165

PubMed: 29746542 ( click the link to review the publication )

Onco Targets Ther, 2018, 11:5703-5713

PubMed: 30254463 ( click the link to review the publication )

J Oncol, 2018, 2018:3979527

PubMed: 30631355 ( click the link to review the publication )

Nucleic Acids Res, 2018, 46(20):10724-10739

PubMed: 30202980 ( click the link to review the publication )

Br J Cancer, 2018, 118(6):e13

PubMed: 29438360 ( click the link to review the publication )

Cell Res, 2017, 27(2):274-293

PubMed: 27958289 ( click the link to review the publication )

Mol Cell, 2017, 67(4):579-593

PubMed: 28781233 ( click the link to review the publication )

Mol Cell, 2017, 68(1):210-223e6

PubMed: 28985505 ( click the link to review the publication )

Nat Commun, 2017, 8(1):1506

PubMed: 29138396 ( click the link to review the publication )

Nat Commun, 2017, 8:15289

PubMed: 28474672 ( click the link to review the publication )

Aging Cell, 2017, 16(3):575-584

PubMed: 28345297 ( click the link to review the publication )

Elife, 2017, 6

PubMed: 28994651 ( click the link to review the publication )

Elife, 2017, 6e30523

PubMed: 29106372 ( click the link to review the publication )

FASEB J, 2017, 32(2):625-638

PubMed: 28970258 ( click the link to review the publication )

Cell Chem Biol, 2017, 24(8):1017-1028

PubMed: 28807782 ( click the link to review the publication )

Cell Physiol Biochem, 2017, 43(2):431-444

PubMed: 28922657 ( click the link to review the publication )
Curr Biol, 2017, 27(10):1477-1484

PubMed: 28479321 ( click the link to review the publication )

Mol Cancer Ther, 2017, 16(1):3-15

PubMed: 27760837 ( click the link to review the publication )

FEBS J, 2017, 284(23):4035-4050

PubMed: 28985013 ( click the link to review the publication )

J Cell Physiol, 2017, 232(10):2818-2828

PubMed: 27861885 ( click the link to review the publication )

Sci Rep, 2017,

PubMed: 28387346 ( click the link to review the publication )

Sci Rep, 2017, 7(1):8629

PubMed: 28819179 ( click the link to review the publication )

J Biol Chem, 2017, 292(36):15028-15038

PubMed: 28739871 ( click the link to review the publication )

Cell Signal, 2017, 39:74-83

PubMed: 28780319 ( click the link to review the publication )

Am J Physiol Cell Physiol, 2017, 313(5):C501-C515

PubMed: 28794108 ( click the link to review the publication )

PLoS One, 2017, 12(1):e0170650

PubMed: 28125646 ( click the link to review the publication )

Biochem Biophys Res Commun, 2017, 484(4):864-870

PubMed: 28188792 ( click the link to review the publication )

Oncotarget, 2017, 9(13):10920-10933

PubMed: 29541386 ( click the link to review the publication )

Oncotarget, 2017, 8(23):37633-37645

PubMed: 28430578 ( click the link to review the publication )

Nat Chem Biol, 2016, 10.1038/nchembio.2017

PubMed: 26829474 ( click the link to review the publication )

Nat Commun, 2016, 7:11363

PubMed: 27193833 ( click the link to review the publication )

Nat Commun, 2016, 7:10818

PubMed: 26912231 ( click the link to review the publication )

Nat Chem Biol, 2016, 12(6):411-8

PubMed: 27043190 ( click the link to review the publication )

Elife, 2016, 5:e11402

PubMed: 26878753 ( click the link to review the publication )

PLoS Pathog, 2016, 12(8):e1005860

PubMed: 27579920 ( click the link to review the publication )

Mol Cancer Ther, 2016, 15(1):48-59

PubMed: 26586723 ( click the link to review the publication )

J Virol, 2016, 90(6):2794-805

PubMed: 26719254 ( click the link to review the publication )

Sci Rep, 2016, 6:19567

PubMed: 26777522 ( click the link to review the publication )

J Biol Chem, 2016, 10.1074/jbc.M116.722751

PubMed: 27226586 ( click the link to review the publication )

J Biol Chem, 2016, 10.1074/jbc.M115.712745

PubMed: 27325694 ( click the link to review the publication )
J Biol Chem, 2016, 291(20):10904-15

PubMed: 27002159 ( click the link to review the publication )

Cell Cycle, 2016, 15(15):2009-18

PubMed: 27249336 ( click the link to review the publication )

PLoS One, 2016, 11(4):e0153818

PubMed: 27097159 ( click the link to review the publication )

Oncotarget, 2016, 7(18):26580-92

PubMed: 27058891 ( click the link to review the publication )

Oncotarget, 2016, 7(12):15215-29

PubMed: 26934655 ( click the link to review the publication )

Head Neck, 2016, 10.1002/hed.24349

PubMed: 26713885 ( click the link to review the publication )

Nat Cell Biol, 2015, 17(2):113-22

PubMed: ( click the link to review the publication )

Nat Cell Biol, 2015, 17(2):113-22

PubMed: 25599390 ( click the link to review the publication )

Nat Cell Biol, 2015, 17(1):31-43

PubMed: 25503564 ( click the link to review the publication )

Nat Cell Biol, 2015, 17(8):1024-35

PubMed: 26192437 ( click the link to review the publication )

Nat Commun, 2015, 6:8388

PubMed: 26399523 ( click the link to review the publication )

Nat Commun, 2015, 10.1038/ncomms8217

PubMed: 26147444 ( click the link to review the publication )

Nat Commun, 2015, 6:6891

PubMed: 25922916 ( click the link to review the publication )

Nat Commun, 2015, 6:8077

PubMed: 26293378 ( click the link to review the publication )

Nat Commun, 2015, 6:6946

PubMed: 25897860 ( click the link to review the publication )

Nat Commun, 2015, 6:10076

PubMed: 26647647 ( click the link to review the publication )

Nat Commun, 2015, 6:10072

PubMed: 26656453 ( click the link to review the publication )

Genes Dev, 2015, 29(18):1969-79

PubMed: 26385965 ( click the link to review the publication )

Cancer Res, 2015, 75(2):405-14

PubMed: 25480943 ( click the link to review the publication )

J Control Release, 2015, 204:20-9

PubMed: 25681050 ( click the link to review the publication )

J Control Release, 2015, 204:20-29

PubMed: ( click the link to review the publication )

Cancer Lett, 2015, 357(2):591-601

PubMed: 25524551 ( click the link to review the publication )

Mol Oncol, 2015, 9(2):527-43

PubMed: 25454348 ( click the link to review the publication )

Mol Cell Proteomics, 2015, 14(4):946-60

PubMed: 25659891 ( click the link to review the publication )
J Neurochem, 2015, 10.1111/jnc.13085

PubMed: 25727910 ( click the link to review the publication )

J Biol Chem, 2015, 290(5):3033-44

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J Biol Chem, 2015, 290(49):29617-28

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Mol Biol Cell, 2015, 26(3):440-52

PubMed: ( click the link to review the publication )

Cell Cycle, 2015, 14(2):219-31

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Oncotarget, 2015, 6(4):2315-30

PubMed: 25537513 ( click the link to review the publication )

Oncotarget, 2015, 6(7):5275-91

PubMed: 25779659 ( click the link to review the publication )

Oncotarget, 2015, 6(11):9327-40

PubMed: 25871386 ( click the link to review the publication )

Oncotarget, 2015, 6(33):34475-93

PubMed: 26439686 ( click the link to review the publication )

Nat Cell Biol, 2014, 16(6):538-49

PubMed: 24776885 ( click the link to review the publication )

Clin Cancer Res, 2014, 20(12):3211-21

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Cancer Res, 2014, 74(20):5878-90

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ACS Chem Biol, 2014, 9(5):1160-71

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Antimicrob Agents Chemother, 2014, 13(5):1054-66

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J Biol Chem, 2014, 289(38):26344-56

PubMed: 25100726 ( click the link to review the publication )

J Biol Chem, 2014, 289(18):12313-29

PubMed: 24634213 ( click the link to review the publication )

J Biol Chem, 2014, 289,14066-14074

PubMed: ( click the link to review the publication )

J Biol Chem, 2014, 289(20):14066-74

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Cell Cycle, 2014, 13(23):3685-97

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Cell Cycle, 2014, 13(2):303-14

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Cell Cycle, 2014, 13(24):3867-77

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Cell Cycle, 2014, 13(14):2248-61

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Biosci Rep, 2014, 34(3)

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PLoS One, 2014, 9(10):e111146

PubMed: 25343454 ( click the link to review the publication )
PLoS One, 2014, 9(12):e115228

PubMed: 25542032 ( click the link to review the publication )

PLoS One, 2014, 8(10):e77053

PubMed: 24204733 ( click the link to review the publication )

Oncotarget, 2014, 5(3):667-78

PubMed: 24525428 ( click the link to review the publication )

Oncotarget, 2014, 5(18):8379-92

PubMed: 25268741 ( click the link to review the publication )

The University of Queensland, 2014, Fawzi Faisal A. Bokhari

PubMed: ( click the link to review the publication )

Assay Drug Dev Technol, 2014, 12(9-10):514-26

PubMed: 25506801 ( click the link to review the publication )

Dev Cell, 2013, 25(6):555-71

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Proc Natl Acad Sci USA, 2013, 110(32):13026-31

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Genes Dev, 2013, 27(20):2259-73

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Cancer Res, 2013, 73(22):6722-33

PubMed: 24101154 ( click the link to review the publication )

Cancer Res, 2013, 73(2):813-23

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Cancer Res, 2013, 73(20):6310-22

PubMed: 24067506 ( click the link to review the publication )

Cell Rep, 2013, 4(4):803-16

PubMed: 23972993 ( click the link to review the publication )

Oncogene, 2013, 10.1038/onc.2013.518

PubMed: 24317508 ( click the link to review the publication )

Br J Cancer, 2013, 110(2):510-9

PubMed: 24327015 ( click the link to review the publication )

Gynecol Oncol, 2013, 128(3):461-9

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J Cell Sci, 2013, 126(Pt 16):3627-37

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J Biol Chem, 2013, 288(33):23765-75

PubMed: 23814058 ( click the link to review the publication )

J Biol Chem, 2013, 288(20):14158-69

PubMed: 23504319 ( click the link to review the publication )

Invest Ophthalmol Vis Sci, 2013, 54(13):8353-63

PubMed: 24366665 ( click the link to review the publication )

Cancer Biol Ther, 2013, 14(5):436-49

PubMed: 23377828 ( click the link to review the publication )

Cell Cycle, 2013, 12(14):2255-65

PubMed: 24067368 ( click the link to review the publication )

PLoS One, 2013, 8(10):e77390

PubMed: 24155950 ( click the link to review the publication )

J Biomol Screen, 2013, 18(1):54-66

PubMed: 22923784 ( click the link to review the publication )
Biol Open, 2013, 2(5):479-86

PubMed: 23789096 ( click the link to review the publication )

Biol Open, 2013, 2(10):1022-31

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Cancer Res, 2013, 73(22):6667-78

PubMed: 23983103 ( click the link to review the publication )

Cell Cycle, 2013, 12(9):1340-51

PubMed: 23574746 ( click the link to review the publication )

J Biol Chem, 2012, 287(6):4376-85

PubMed: 22184120 ( click the link to review the publication )

J Biol Chem, 2012, 287(21):17088-99

PubMed: 22467873 ( click the link to review the publication )

Cell Cycle, 2012, 11(3):543-53

PubMed: 22262171 ( click the link to review the publication )

PLoS One, 2012, 7(10):e46546

PubMed: 23056340 ( click the link to review the publication )

PLoS One, 2012, 7(6):e38838

PubMed: 22701722 ( click the link to review the publication )

Biotechniques, 2012, 10.2144/000113866

PubMed: ( click the link to review the publication )

Biotechniques, 2012, 53(1)

PubMed: 26307252 ( click the link to review the publication )

Nat Cell Biol, 2011, 13(10):1265-71

PubMed: 21874008 ( click the link to review the publication )

Cancer Res, 2011, 71(4):1385-95

PubMed: 21303981 ( click the link to review the publication )

Cancer Res, 2011, 71(17):5659-69

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J Cell Biol, 2011, 193(6):1083-99

PubMed: 21646404 ( click the link to review the publication )

Oncogene, 2011, 30(46):4666-77

PubMed: 21602893 ( click the link to review the publication )

J Invest Dermatol, 2011, 131(9):1886-95

PubMed: 21654832 ( click the link to review the publication )

Purity & Quality Control

Choose Selective PLK Inhibitors

Biological Activity

Description

Features

The first potent and selective Plk1 inhibitor that induces all hallmarks of Plk1 inhibition.

Targets

c-Myc ^[3] ()	PLK1 ^[1] (Cell-free assay)	PLK2 ^[1] (Cell-free assay)	PLK3 ^[1] (Cell-free assay)	BRD4 ^[3] (Cell-free assay)
	0.83 nM	3.5 nM	9.0 nM	37 nM(Kd)

In vitro

BI 2536 blocks the activities of Plk2 and Plk3 to a slightly lesser extent with IC50 of 3.5 nM and 9.0 nM, respectively. In HeLa cells, BI 2536 treatment ranging from 10-100 nM leads to the blocking of the recruitment of γ-tubulin and phosphorylation of Apc6 at mitotic centrosomes, inhibition of cohesin release from chromosome arms, induction of monopolar spindles, as well as a range of other mitotic processes that are known to depend on Plk1. BI 2536 treatment leads to the HeLa cells arrested in G2/M, subsequently a sub-G1 DNA peak indicative of DNA breakdown and apoptosis, and accumulated cleaved PARP p85 fragments in a concentration-dependent manner. BI 2536 inhibits the growth of a panel of 32 human cancer cell lines with EC50 of 2-25 nM, while blocking the proliferation of exponentially growing hTERT-RPE1, human umbilical vein endothelial cells (HUVECs), and normal rat kidney (NRK) cells with EC50 of 12-31 nM. ^[1] Plk1 inhibition by BI 2536 reduces the growth and viability of anaplastic thyroid carcinoma (ATC) cells such as CAL62, OCUT-1, SW1736, 8505C, and ACT-1 with EC50 values of 1.4-5.6 nM. ^[2]

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID
PSN1	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MUXJR\|UxRTBwMEC3O\|Yh\|ryP	NHLkW5A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
ACN	MofhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWPnU\|lxUUN3ME2wMlAxQDR\|IN88US=>	NYDsOIdSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
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LC-2-ad	MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NHztenNKSzVyPUCuNFExQTNizszN	MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
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BB65-RCC	M1XlXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MlPlTWM2OD1yLkGwNlk1KM7:TR?=	Mnv6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
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NCI-H526	M2juPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1\p[GlEPTB;MD6xNFQ1KM7:TR?=	M3nWNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
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HD-MY-Z	M2TCU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1L4NWlEPTB;MD6xNFg2PiEQvF2=	NWD5clJYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
K-562	M4fmNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NXj5ZWdOUUN3ME2wMlExQDV6IN88US=>	NUWwOox6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
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SCC-3	NGDINIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M{fDb2lEPTB;MD61NVg4OyEQvF2=	NV;Dbo1sRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
KLE	NEHVbotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1fKRmlEPTB;MD61NlE4OSEQvF2=	NHnifFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
LB2241-RCC	M33ZdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVjJR\|UxRTBwNUK1NlUh\|ryP	NV3ZfIE2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NCI-H1417	M2jySWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NXLrVY16UUN3ME2wMlU{PDN3IN88US=>	NWC0Z21zRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NCI-H2081	MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGrMVlRKSzVyPUCuOVg3OTFizszN	Mn7LQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
NCI-H1522	NHewVXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVv3S3B4UUN3ME2wMlU6Ozh\|IN88US=>	NXnZSVJxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NCI-H889	NY\4b4dLT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFnKU2RKSzVyPUCuOVk5PDRizszN	MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
CGTH-W-1	M1S3Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3;PNWlEPTB;MD62NFc2PSEQvF2=	NYTrZplORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
EB-3	MlO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYjxbGgzUUN3ME2wMlYyOTV\|IN88US=>	MmfJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
D-336MG	M1[3OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1zFbGlEPTB;MD62NVc6OSEQvF2=	M37ZSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
LC-1F	NIXrRphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NH\3To9KSzVyPUCuOlI2QTJizszN	NX\WPHNVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
MHH-NB-11	MnfOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MULJR\|UxRTBwNkO4NFEh\|ryP	NVXCOpo3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
SK-N-FI	NVfrNlBpT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXTJR\|UxRTBwNkO5NUDPxE1?	NYjOUJE3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NCI-H69	M2r3[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVPJR\|UxRTBwNkS4O\|kh\|ryP	M2j2OVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
SCH	NX[2dJJlT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NEjMTmtKSzVyPUCuOlYxOjNizszN	MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
LS-513	MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Mm\ZTWM2OD1yLk[3NlU6KM7:TR?=	Mlz4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
CP67-MEL	M2HkSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVfJR\|UxRTBwNke1PVYh\|ryP	MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
GCIY	Ml:xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MWjJR\|UxRTBwN{CzOlMh\|ryP	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
SHP-77	NEiyeFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYrYNGk6UUN3ME2wMlcxPzN2IN88US=>	MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
EHEB	MkPtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVrPfpR3UUN3ME2wMlcyQDV2IN88US=>	NEfCb4Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
D-247MG	NFr5VmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFHO[\|hKSzVyPUCuO\|MzOzJizszN	M4KxdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
Raji	MoOyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXjRZ2FKUUN3ME2wMlc1QTh7IN88US=>	NFrJTIo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
MPP-89	MmLZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFnFdIJKSzVyPUCuO\|U6PzhizszN	M{XXZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
EKVX	NYrPfHhoT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NV33d2JPUUN3ME2wMlc6ODd\|IN88US=>	MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
HCC2218	NI\5OnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MlLOTWM2OD1yLke5NVMyKM7:TR?=	NVnkO3Z7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
KNS-81-FD	M4rKRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVrJR\|UxRTBwOEGwNVEh\|ryP	NGD3WI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
HCC2157	NXu5WphtT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmXBTWM2OD1yLki0PVUyKM7:TR?=	MlHLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
BT-474	NIjGc4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFSxeGhKSzVyPUCuPFg5PTRizszN	NFu3dGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
NCI-H748	Mn\aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYDqfppzUUN3ME2wMlkyOiEQvF2=	NUXk[2Z{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
EW-24	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NIrrN2VKSzVyPUCuPVIxODJizszN	NX\JXXNyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
D-263MG	M1fnRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MY\JR\|UxRTBwOUS1NVIh\|ryP	NI\qeIQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
OMC-1	MnnYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWXrUGU1UUN3ME2wMlk3Ozd\|IN88US=>	MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
NCI-H2196	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXjJR\|UxRTBwOUe3O\|ch\|ryP	MmC1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
HAL-01	MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NVrsXnNiUUN3ME2wMlk6QDd{IN88US=>	NHTLeXM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
NCI-H2107	M3LVdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MYPJR\|UxRTFwMEG4OVQh\|ryP	MnjuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
LB996-RCC	MkjDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NH3rdlZKSzVyPUGuNFgxPTFizszN	Moq4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
NCI-H1395	NWTWRoRsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MlrnTWM2OD1zLkGwOlch\|ryP	NW\LUnpZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
CHP-126	NELpcGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYTJR\|UxRTFwMU[xPVkh\|ryP	NWDsOpF[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NB69	NIXW[YZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MorGTWM2OD1zLkK2NVQ5KM7:TR?=	MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
CAS-1	M2XHR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2PXWmlEPTB;MT6zOFI{OSEQvF2=	MlO4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
JVM-3	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M{TwSWlEPTB;MT60O\|g2PSEQvF2=	M3;zPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
DMS-153	NVvRRplKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mmj4TWM2OD1zLkW3Olc1KM7:TR?=	M{HTNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
SK-MEL-2	NHjBOlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYHJR\|UxRTFwN{G3PFkh\|ryP	MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
NCI-H1155	NXe0[JJST3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MWfJR\|UxRTFwN{O2O\|Yh\|ryP	MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
NCI-H1092	NVHSeZplT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mn\hTWM2OD1zLke2NVgzKM7:TR?=	NWnGc3Q3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
LU-165	M3fv[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mmr4TWM2OD1zLki2OFc3KM7:TR?=	NYnjfINYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
HL-60	NITsUWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVPJR\|UxRTFwOUm5NFgh\|ryP	MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
REH	NWHSdFA2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NHS5SJdKSzVyPUKuNFA2QDJizszN	Ml\CQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
JVM-2	NUHxelk4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mk\rTWM2OD1{LkC2NVM2KM7:TR?=	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
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NCI-H719	M1W5O2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NH7wV5ZKSzVyPUOuN\|A{QDRizszN	MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
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SIMA	NWXFTo0xT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mk\UTWM2OD1\|LkW4OFE3KM7:TR?=	MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
SW872	M1nSRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MnH2TWM2OD1\|Lke4NVAyKM7:TR?=	MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
HCC1187	M3XpSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NXiwNZFuUUN3ME2zMlc5OzF3IN88US=>	M1;oOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
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RPMI-8866	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NEfwVFdKSzVyPUSuN\|YxOjlizszN	NFfQdmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
OCI-AML2	MkH6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYTSUpo5UUN3ME20MlU2OjNizszN	NWLMbodzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
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NB14	MmnjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MojLTWM2OD13Lkm3NVM2KM7:TR?=	MoDmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
COLO-829	M4n6WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MkHiTWM2OD14LkOzN\|U6KM7:TR?=	Mm\FQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
MHH-CALL-2	M2qzdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NVHwVoN5UUN3ME22MlUyPTB6IN88US=>	NUDZXlVoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NCI-H1770	NVHOSldsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXzJR\|UxRTZwNk[5NFQh\|ryP	NIe4TYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
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A498	M2C1OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NVLKZnptUUN3ME22Mlg4OTl{IN88US=>	M3j2VVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
DMS-79	M4G4Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mn7wTWM2OD15LkC0OVEzKM7:TR?=	NXX2WY5TRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
P30-OHK	M4XMcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NU[xNmwzUUN3ME23MlIyQTB4IN88US=>	NH;Qb2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
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MSTO-211H	NVHNTY5xT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3f6[GlEPTB;MkGuPFg2QCEQvF2=	Mn;uQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
U-87-MG	NETHPJVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFHmUHhKSzVyPUK1MlE6PjZizszN	NX;XVIpjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
THP-1	NV3sdItJT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmDtTWM2OD1{OT63NlAyKM7:TR?=	MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
NB10	MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MYHJR\|UxRTNyLkK2PVQh\|ryP	MnXYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
NH-12	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NV3LUIlmUUN3ME2zN{4zODF5IN88US=>	NFfEW4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
COLO-824	NFjFSGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUTlN4xzUUN3ME2zOE4yODB4IN88US=>	NF7DU3U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw2OTN7MEmvK\|5USU6JRWK8M4E,
SKM-1	MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NFP6NY1KSzVyPUO3Mlg1OjJizszN	MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
NCI-H1838	NXrNdXMzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NInUd2hKSzVyPUO4MlM4QTdizszN	MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
RL	Mkf1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MXjJR\|UxRTN7LkK0O\|ch\|ryP	MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
COLO-800	NHS0PVZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFe5UplKSzVyPUSwMlA4PzNizszN	MkfBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
KG-1	MnLwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M2\FXGlEPTB;NECuPFk2PSEQvF2=	M3PjNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFUyOzlyOT:nQnNCVkeHUkyvZV4>
TUR	MkTkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmjYTWM2OD12MT62N\|k6KM7:TR?=	MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly1NVM6ODlxJ{7TRW5ITVJ:L3G+
LNCaP-Clone-FGC	M3jzeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWTJR\|UxRTRzLkmwNVch\|ryP	NXO1eJlxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPTF\|OUC5M{c,W0GQR1XSQE9iRg>?
NCI-H322M	M3nrNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2DJVmlEPTB;NEKuOVk5PCEQvF2=	Mo\LQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOVE{QTB7Lze+V2FPT0WUPD;hQi=>
LNCaP	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkPzTWM2OD17MT6zJI5O	MnfSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV3MEWxO\|QoRjJ3NUC1NVc1RC:jPh?=
C4-2	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MmPXTWM2OD16IH7N	Mmj5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV3MEWxO\|QoRjJ3NUC1NVc1RC:jPh?=
JURKAT	NE\HZlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MoOxNlQhcA>?		M1fIUWlEPTB;NEG2MlY3KG6P	MorrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
MOLT-4	MlvlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MkX3NlQhcA>?		MV7JR\|UxRTJ6NUOuOUBvVQ>?	MlzmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
REH	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NFzuZ5gzPCCq		MUnJR\|UxRTJ6Nz62PEBvVQ>?	MkfDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
NALM-6	MlPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M1u3WVI1KGh?		MmD5TWM2OD1\|NEOzNEBvVQ>?	MkTJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
RS 4;11	NW\lNYEzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		Mn3nNlQhcA>?		NVLvXGh5UUN3ME21NVkvODVibl2=	NEHE[4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEWxPVk6PSd-MkS1NVk6QTV:L3G+
697	NFfzTnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NH:3NGgzPCCq		M4nRRWlEPTB;MkGwO{4yKG6P	MlHHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
SIL-ALL	Mn6yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NIX0[4szPCCq		NFfje4FKSzVyPUG5PU44PyCwTR?=	MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVzOUm5OUc,OjR3MUm5PVU9N2F-
CEM	NWDoe4hnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MX[yOEBp		MYjJR\|UxRTV{LkG4JI5O	NVTHS\|NNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NVk6QTVpPkK0OVE6QTl3PD;hQi=>
P12	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MkjENlQhcA>?		NH;QVFBKSzVyPUO5MlI4KG6P	M13zOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
NALM-16	MoK4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NH\pPHozPCCq		M2[0ZmlEPTB;OU[uNlghdk1?	M4T6SVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
JURKAT	NV2y[HhDT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		MX[0PEBp		NYPVd4ljUUN3ME2xOE45PCCwTR?=	NXPmOWNqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NVk6QTVpPkK0OVE6QTl3PD;hQi=>
MOLT-4	MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MmTsOFghcA>?		MV3JR\|UxRTJ4Lk[gcm0>	MlfGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
REH	MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NHn0PWM1QCCq		M1;Pe2lEPTB;NESuO\|Ehdk1?	MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVzOUm5OUc,OjR3MUm5PVU9N2F-
NALM-6	MlvWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NGPFZos1QCCq		MmD2TWM2OD1{Mz6yOkBvVQ>?	MoLJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
RS 4;11	NGT3[o5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MkXoOFghcA>?		M2TsOWlEPTB;MU[0MlI5KG6P	MnfoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
697	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MYC0PEBp		M4S4cWlEPTB;M{C1MlMhdk1?	NVHGepo1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NVk6QTVpPkK0OVE6QTl3PD;hQi=>
SIL-ALL	NFTpVVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		MXe0PEBp		MX;JR\|UxRTd2Lk[yJI5O	M3PB[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
CEM	MlH4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		Mm[4OFghcA>?		NGrDTXRKSzVyPUK0MlU2KG6P	M3OxOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
P12	MoTaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MoTvOFghcA>?		NXzlNIJkUUN3ME2xPE41PiCwTR?=	M{XOW\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
NALM-16	MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NELUbnc1QCCq		MVXJR\|UxRTZ\|LkK0JI5O	NVLHTpBLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NVk6QTVpPkK0OVE6QTl3PD;hQi=>
JURKAT	M{DxXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MkHPO\|IhcA>?		M4DI[GlEPTB;Mz62OUBvVQ>?	NGXkVos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEWxPVk6PSd-MkS1NVk6QTV:L3G+
MOLT-4	MnPPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		MXq3NkBp		NFy5V3hKSzVyPUeuN\|khdk1?	MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVzOUm5OUc,OjR3MUm5PVU9N2F-
REH	NXPYVnpuT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		NGDi[JQ4OiCq		MYnJR\|UxRTF4LkCxJI5O	M{XXe\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
NALM-6	NYrrNlhuT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=		M1nye\|czKGh?		NU\lZmNNUUN3ME2xMlc5KG6P	NUWyXoc4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NVk6QTVpPkK0OVE6QTl3PD;hQi=>
RS 4;11	M2jkVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7		MUO3NkBp		NVT0c3hqUUN3ME20MlM5KG6P	MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVzOUm5OUc,OjR3MUm5PVU9N2F-
697	MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		NWTqOI9pPzJiaB?=		NYfWUYJ[UUN3ME23OE4zQCCwTR?=	M1XuO\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
SIL-ALL	NEL1[W1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		M2Cze\|czKGh?		NY\5TFFiUUN3ME23MlIhdk1?	MkP0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR3MUm5PVUoRjJ2NUG5PVk2RC:jPh?=
CEM	MluxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NXjKT\|VmPzJiaB?=		M4DrdWlEPTB;NT60NkBvVQ>?	MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVzOUm5OUc,OjR3MUm5PVU9N2F-
P12	MonBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		NW\wUGd6PzJiaB?=		MYjJR\|UxRTZwM{egcm0>	MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDVzOUm5OUc,OjR3MUm5PVU9N2F-
NALM-16	NESyNZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NW\OVmdbPzJiaB?=		MVzJR\|UxRTd5LkezJI5O	M2\yUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NUG5PVk2Lz5{NEWxPVk6PTxxYU6=
Y79	Mlv2RZBweHSxc3nzJGF{e2G7	NFnEdJkyNTVyIH7N	M3;rOVEzNzJ2IHi=	MUjEUXNQ	MWnpcoR2[2WmIHHwc5B1d3OrczD3bIlkcCClYX6gZoUh\W6qYX7j[YQh[nliSGS=	NF2zW5Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2OlY3PSd-MkSzOlY3PjV:L3G+
WER-Rb-1	M2L4cWFxd3C2b4Ppd{BCe3OjeR?=	M4DwRVEuPTBibl2=	MnKwNVIwOjRiaB?=	M2G2cmROW09?	MnHKbY5lfWOnZDDhdI9xfG:\|aYOge4hq[2hiY3HuJIJmKGWwaHHuZ4VlKGK7IFjU	MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN4Nk[2OUc,OjR\|Nk[2OlU9N2F-
G7	NHzPWYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVXGbYNyUUN3ME2zMlMhdk1?	MnrXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR{MES3N\|MoRjJ2MkC0O\|M{RC:jPh?=
G166	NX:weXBnT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NYXNTGtyUUN3ME23MlAhdk1?	NUPtWXF1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSyNFQ4OzNpPkK0NlA1PzN\|PD;hQi=>
CB660	NVrhbVhET3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NULTcXRRUUN3ME22MlQhdk1?	NFntU3M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEKwOFc{Oyd-MkSyNFQ4OzN:L3G+
CB1117	M2\nOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MmjyTWM2OD1zNT62JI5O	NFLoU\|M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEKwOFc{Oyd-MkSyNFQ4OzN:L3G+
KB-3-1	NHvPNXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NH:wS2tKSzVyPUGuOFghyrFiMD61N{BvVQ>?	M4fZOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|OU[yOFQ2Lz5{M{m2NlQ1PTxxYU6=
KB-8-5-11	MnLaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Ml7mTWM2OD13LkCxJOKyKDJwMEGgcm0>	NHTsR449[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2NlQ1PSd-MkO5OlI1PDV:L3G+
KB-C-1	MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MnPMTWM2OD1zNj63OkDDuSB2LkWxJI5O	NVHwdng1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5OlI1PDVpPkKzPVYzPDR3PD;hQi=>
KB-V-1	MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MX3JR\|UxRTJ6MT6yOEDDuSB\|MT61O{BvVQ>?	NF60WpM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2NlQ1PSd-MkO5OlI1PDV:L3G+
OVCAR-8	M1HGV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M4f4V2lEPTB;Nz6xPUDDuSB\|Lk[wJI5O	Mn7QQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7NkK0OFUoRjJ\|OU[yOFQ2RC:jPh?=
NCI-ADR-RES	MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NYjPZnFsUUN3ME2xNlc{NjNyINMxJFE6OS5{MDDuUS=>	MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl4MkS0OUc,OjN7NkK0OFU9N2F-
MCF7	M3TWdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NFHS[GpKSzVyPUWuNVEhyrFiMT60O{BvVQ>?	NWPT[lJmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5OlI1PDVpPkKzPVYzPDR3PD;hQi=>
MCF7-FLV1000	MnHmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkX6TWM2OD1\|OUOuNVghyrFiN{SuPFMhdk1?	MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl4MkS0OUc,OjN7NkK0OFU9N2F-
S1	MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MUfJR\|UxRTJ2LkOwJOKyKDRwN{Wgcm0>	MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzl4MkS0OUc,OjN7NkK0OFU9N2F-
S1-M1-80	MlnxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXuyU4s4UUN3ME2yOlEvODZiwsGgOFgvOjVibl2=	NFLObJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2NlQ1PSd-MkO5OlI1PDV:L3G+
CORL-23/P	NX;nVlFyT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NGDFdYFKSzVyPUSuN\|ghyrFiMT6yOUBvVQ>?	NFPvNXA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2NlQ1PSd-MkO5OlI1PDV:L3G+
CORL-23/R	MkDYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MWTJR\|UxRTVwMU[gxtEhOS56MzDuUS=>	M{jQc\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|OU[yOFQ2Lz5{M{m2NlQ1PTxxYU6=
NIH3T3	NX3EdXdWT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M4T0S2lEPTB;NECuOlAhyrFiND65O{BvVQ>?	M4T2NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|OU[yOFQ2Lz5{M{m2NlQ1PTxxYU6=
NIH3T3-G185	NGnVO5lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MoPlTWM2OD1{NEGzMlQxKMLzIESyN{43PiCwTR?=	NEPRe2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2NlQ1PSd-MkO5OlI1PDV:L3G+
pcDNA-HEK293	NEK3THdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MUDJR\|UxRTJwN{WgxtEhOC54NzDuUS=>	Mk[zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN7NkK0OFUoRjJ\|OU[yOFQ2RC:jPh?=
MDR19-HEK293	MnzZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1;JVGlEPTB;OEWuOVAhyrFiMUOuOlchdk1?	NX7Y[FZHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5OlI1PDVpPkKzPVYzPDR3PD;hQi=>
R482-HEK293	NV7lXHdvT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NXP6VZF1UUN3ME2yOU46PyEEsTC0Mlk2KG6P	NYO1emw5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO5OlI1PDVpPkKzPVYzPDR3PD;hQi=>
MRP1-HEK293	NITUcmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1zHe2lEPTB;Mj65PUDDuSBzLkS5JI5O	NFnJS3Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{m2NlQ1PSd-MkO5OlI1PDV:L3G+
SF188	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	M3\zR\|ExNTFyMDDuUS=>	Mom2NlQuQTZiaB?=	NVf5VGZMTE2VTx?=	M1nQXIlvcGmkaYTzJINmdGxiZ4Lve5RpKGmwIHLveIghfGmvZT2gZY5lKGOxbnPlcpRz[XSrb36tJIRmeGWmZX70JI1idm6nch?=	MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{[0OUc,OjN6OEe2OFU9N2F-
T98G	NVXS[JJiT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	M4\EcFExNTFyMDDuUS=>	M2S2TVI1NTl4IHi=	NVHpUHQxTE2VTx?=	NGixTXlqdmirYnn0d{Bk\WyuIHfyc5d1cCCrbjDjc45k\W62cnH0bY9vNSCmZYDl[IVvfCCvYX7u[ZI>	MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6N{[0OUc,OjN6OEe2OFU9N2F-
DU145	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?			NG\KNopFVVOR	NEK5XnZKSzVy4pk8OlAhdk1?	Mn7wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OES0NlgoRjJ\|OEi0OFI5RC:jPh?=
LNCaP	M4jxdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7			NHixVoRFVVOR	NWjVR3pZUUN3MPMIwFc2KG6P	MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh6NESyPEc,OjN6OES0Nlg9N2F-
PC3	Mn:3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?			MmDwSG1UVw>?	MV\JR\|Ux6oj:MUe1JI5O	MlLWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6OES0NlgoRjJ\|OEi0OFI5RC:jPh?=
RT4	M3fkZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MkDsTWM2OD1{Nz6yNUBvVQ>?	MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzd7Mk[zPUc,OjN5OUK2N\|k9N2F-
5637	NFK0fIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MUHJR\|UxRTR3LkS3JI5O	NISzZ4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{e5NlY{QSd-MkO3PVI3Ozl:L3G+
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MCF7	NU\0Woo6TnWwY4Tpc44hSXO\|YYm=	NILndoYyODBibl2=	NV;0bGpmOSCq	MoXCSG1UVw>?	NEe0dY1z\WS3Y3XzJJRp\SCrbnT1Z5Rqd25ib3dCpGdz\WJzLNMgV4dsOS{EoGDzNkzDqFOncoDpcoE{NCCjbnVCpHdqe3B{	NWXnfYlzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3O\|AzPDRpPkKzO\|cxOjR2PD;hQi=>
KB-V1	MkXYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4npS2lEPTB;Mz65NkDPxE1?	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV7M{G5Okc,OjN3OUOxPVY9N2F-
Hec50co	Mo\hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mmm1TWM2OD13IH7N	M1fwWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MUS2Olg4Lz5{M{G0OlY5PzxxYU6=
MDA-MB-468	MX\BdI9xfG:\|aYOgRZN{[Xl?	MVSxM\|UwOTBibl2=	M3voUVI1NzR6L{eyJIg>	NXzadJN1TE2VTx?=	NWe3VpMzcW6mdXPld{BieG:ydH;zbZMhcW5iYTDkc5NmNWSncHXu[IVvfCCvYX7u[ZI>	Ml;6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNESyPVQoRjJ\|MUS0Nlk1RC:jPh?=
MCF10A	MVLBdI9xfG:\|aYOgRZN{[Xl?	MV2xM\|UwOTBibl2=	MWiyOE81QC95MjDo	MnrwSG1UVw>?	M1juOolv\HWlZYOgZZBweHSxc3nzJIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnXy	NWTaeHdGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOFQzQTRpPkKzNVQ1Ojl2PD;hQi=>
Huh-7	MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MnfNNU8yOC9zMECvNVAxOCCwTR?=	M3TVdlQ5KGh?		M3HzTIRm[3KnYYPld{B1cGViY3XscEB3cWGkaXzpeJkh\G:\|ZT3k[ZBmdmSnboTsfS=>	M3uzPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{S1OVg4Lz5{Mke0OVU5PzxxYU6=
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ONS-76	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MWWxMlg4PS1{NECgcm0>	MnW4O\|IhcA>?	M3\LdWROW09?	MUPJR\|UxRTdwNTDuUS=>	Mni3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ\|OUCyO\|koRjJ{M{mwNlc6RC:jPh?=
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MDA-MB-231	MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?	MoT4NE0yODBibl2=	NUX0T\|BUPzJiaB?=		MmribY5pcWKrdIOgeIhmKGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnHy	M4f0[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{M{C5PVM6Lz5{MkOwPVk{QTxxYU6=
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BT-474-M1	MorCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	MnTyNE0yODBibl2=	NEfIZYw4OiCq		NETVT\|lqdmirYnn0d{B1cGViY3XscEB3cWGkaXzpeJkhcW5iYTDkc5NmNWSncHXu[IVvfCCvYX7uZZI>	Ml7xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ\|MEm5N\|koRjJ{M{C5PVM6RC:jPh?=
AU565	NHLNWHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXmwMVExOCCwTR?=	M2e2SVczKGh?		Mk\wbY5pcWKrdIOgeIhmKGOnbHygeoli[mmuaYT5JIlvKGFiZH;z[U1l\XCnbnTlcpQhdWGwbnHy	NU\DRpBzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKzNFk6OzlpPkKyN\|A6QTN7PD;hQi=>
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MCF7	MlzTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Mn7VNE0yODBibl2=	NHvhPXQ4OiCq		M4jtbIlvcGmkaYTzJJRp\SClZXzsJJZq[WKrbHn0fUBqdiCjIHTvd4Uu\GWyZX7k[Y51KG2jbn7hdi=>	MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjNyOUmzPUc,OjJ\|MEm5N\|k9N2F-
HCT116p53(+/+)	M1PXS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M{frflExNTFyMECgcm0>	MmS4NlQwPDhiaB?=		M37nOolvcGmkaYTzJINmdGxicILvcIln\XKjdHnvckBkd22ybHX0[Yx6KGG2IEK1JI5O	M3fpW\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Mk[yNVcyLz5{MkK2NlE4OTxxYU6=
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TY82	MkjORY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl?		MWe3NkBpenN?		NGf0VZJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGTZPFIh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPDT\|gh[XO\|YYmsJGlEPTBiPTCwMlAxOSEQvF2u	NFHMVII9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEW4OlcyQCd-Mki1PFY4OTh:L3G+
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MV4-11	MkHZR5l1d3SxeHnjbZR6KGG\|c3H5		M{DUeFI1KGi{cx?=		Mke0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUXY1NTFzIHPlcIx{KGGodHXyJFI1KGi{czDifUBE\WyuVHn0[ZIuSmy3ZTDhd5NigSxiR1m1NEA:KDBwMEG1NkDPxE1w	MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjF7MUO2N{c,OjZzOUGzOlM9N2F-
BL21(DE3)	NGDQPXNHfW6ldHnvckBie3OjeR?=		NIjoXHE3OCCvaX7z		MlvVTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCQLYTldo1qdmGuIFjpd\|YufGGpZ3XkJGJTTDRiZYjwdoV{e2WmIHnuJGV{[2incnnjbIliKGOxbHmgRmwzOSiGRUOpJINmdGy\|IIXzbY5oKGKrb4Tpcplt[XSnZDDobZN1d26nIFi0JJBmeHSrZHWgZZMhe3Wkc4TyZZRmKGGodHXyJFYxKG2rboOgZpkhSWyyaHHTZ5Jm\W5iYYPzZZktKEmFNUCgQUAxNjB{NTFOwG0v	NFn5PJQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEG5OVczOyd-MkixPVU4OjN:L3G+
BL21(DE3)	MX7GeY5kfGmxbjDhd5NigQ>?				M4rLdWlvcGmkaYTpc44hd2ZiaIXtZY4hVi22ZYLtbY5idCCKaYO2MZRi\2enZDDCVmQ1NUKGMTCoOFQhfG9iMU[4JJJme2mmdXXzLUBmgHC{ZYPz[YQhcW5iRYPjbIVzcWOqaXGgZ49tcSCETEKxJEhFTTNrIHPlcIx{KHW\|aX7nJJBzd3SnaX6geIhmem2jbDDzbIlnfCCmeXWgZZMh\my3b4Lld4NmdmOnIIDyc4JmKGK7IHTp[oZmemWwdHnhcEB{[2Gwbnnu[{BndHWxcnnt[ZRzgSxiSVO1NEA:KDBwMEK1JO69VS5?	NHz2UIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEW4OlcyQCd-Mki1PFY4OTh:L3G+
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HL60	NULwPJF6S3m2b4TvfIlkcXS7IHHzd4F6		NHq2eJM{KGSjeYO=		Mn:5R5l1d3SxeHnjbZR6KGGpYXnud5QhSlKGNDDk[ZBmdmSnboSgbJVu[W5iSFy2NEBk\WyuczDhd5Nme3OnZDDhd{Bk\WyuII\pZYJqdGm2eTDh[pRmeiB\|IHThfZMh[nliQWTQcIl1\SCjc4PhfUwhUUN3MDC9JFAvODN4NTFOwG0v	M4TZclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OUi1Nlg2Lz5{Nkm4OVI5PTxxYU6=
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MCF7	MnfRRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl?		MWq3NkBpenN?		MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KEOFS{igZZN{[XluIFfJOVAhRSByLkC2O{DPxE1w	NYDte2tMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmyNlA4QTNpPkK5NlIxPzl\|PD;hQi=>
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MDA-MB-23	NV7Qb4xNTnWwY4Tpc44h[XO\|YYm=		MWm2JIhzew>?		M4jnVWlvcGmkaYTpc44hd2ZiUFzLNUBqdiCqdX3hckBOTEFvTVKtNlMh[2WubIOgZZN{\XO\|ZXSgZZMh\GWlcnXhd4UhcW5iVFPUVEBxcG:\|cHjvdplt[XSrb36gZYZ1\XJiNjDodpMh[nliV3XzeIVzdiCkbH;0JI1mfGixZDygTWM2OCB;IECuNUDPxE1w	MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd7Mke2NEc,Ojh5OUK3OlA9N2F-
HEK293T	M3WwWmZ2dmO2aX;uJIF{e2G7		Mkj3OkBpenN?		NEPOdWJKdmirYnn0bY9vKG:oIGDMT\|EhcW5iSFXLNlk{XCClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDUR3RRKHCqb4PwbI9zgWyjdHnvckBi\nSncjC2JIhzeyCkeTDX[ZN1\XKwIHLsc5QhdWW2aH;kMEBKSzVyIE2gNE4yKM7:TT6=	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd7Mke2NEc,Ojh5OUK3OlA9N2F-
NCI-H1975	NXnSdVZESW62aYDyc4xq\mW{YYTpeoUh[XO\|YYm=		MWS3NkBpenN?		NHvOcllCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JOTl5NTDj[YxteyCjZoTldkA4OiCqcoOgZpkhS0ONODDhd5NigSxiR1m1NEA:KDBwMkOg{txONg>?	MnqxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl{MkC3PVMoRjJ7MkKwO\|k{RC:jPh?=
BL21(DE3)	MUjGeY5kfGmxbjDhd5NigQ>?		MWG0JIhzew>?		M2\vVGlvcGmkaYTpc44hd2ZiSmGxMWZKXENiYnnu[Ilv\yC2bzDIbZM3NXSjZ3fl[EBDWkR2LVLENUApfW6tbn;3ckBwemmpaX6pJIV5eHKnc4Pl[EBqdiCHc3Po[ZJq[2irYTDjc4xqKEKOMkGgLGRGOylvY3;kc44heGy3cz3STWwh[2WubIOgbY5kfWKjdHXkJIlvKGSjcnug[o9zKDRiaILzJIJ6KG[udX;y[ZNk\W6lZTDhcol{d3S{b4D5JIF{e2G7LDDJR\|UxKD1iMD6yOUDPxE1w	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDV6NkexPEc,Ojh3OE[3NVg9N2F-
TC32	MmHudWhVWyCjc4PhfS=>				MoLodWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohWHKrbXHyfUB{[3KnZX6g[o9zKFSFM{KgZ4VtdHN?	M17mVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6=
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Saos-2	MX3xTHRUKGG\|c3H5				MUXxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW\|IH\vdkBlenWpIILldJVzeG:\|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhW2Gxcz2yJINmdGy\|	NGDSNHg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
BT-37	MV7xTHRUKGG\|c3H5				NVz0OGM{eUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiUILpcYFzgSC\|Y4Ll[Y4h\m:{IFLUMVM4KGOnbHzz	NFzuTnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
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BT-12	Mn\jdWhVWyCjc4PhfS=>				MV;xTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW\|IH\vdkBlenWpIILldJVzeG:\|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhSlRvMUKgZ4VtdHN?	NFXOPHo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
NB1643	NF7Zdm9yUFSVIHHzd4F6				MnPndWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohWHKrbXHyfUB{[3KnZX6g[o9zKE6EMU[0N{Bk\Wyucx?=	NITI[Yg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
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BT-12	MmHKdWhVWyCjc4PhfS=>				NV;wSXdjeUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiQ3;u[olzdWG2b4L5JJNkemWnbjDmc5IhSlRvMUKgZ4VtdHN?	NHm5XZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
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Fibroblast cells	NGeydXdyUFSVIHHzd4F6				MYfxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW\|IH\vdkBlenWpIILldJVzeG:\|aX7nPkBRemmvYYL5JJNkemWnbjDmc5Ih[2:wdILvcEBJcCC5aXzkJJR6eGViZnnido9jdGG\|dDDj[Yxtew>?	M1\EZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6=
NB-EBc1	Mmm5dWhVWyCjc4PhfS=>				M4fvWpFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KEOxbn\pdo1ifG:{eTDzZ5Jm\W5iZn;yJG5DNUWEY{GgZ4VtdHN?	MmHwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
SK-N-SH	NEDpcHByUFSVIHHzd4F6				MnjQdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohS2:wZnnycYF1d3K7IIPjdoVmdiCob4KgV2suVi2VSDDj[Yxtew>?	NWeyfGo{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N\|UyOzlpPkK5OFM2OTN7PD;hQi=>
A673	M3LWR5FJXFNiYYPzZZk>				NI[1XnByUFSVIH;mJJBm\GmjdILpZ{Bk[W6lZYKgZ4VtdCCuaX7ld{B1dyCrZHXueIlngSCvdXz0bZBt\SCxcIDvdpR2dmm2aXXzJIZweiCmcoXnJJJmeHW{cH;zbY5oQiCFb37mbZJu[XSxcomgd4Nz\WWwIH\vdkBCPjd\|IHPlcIx{MQ>?	MmTLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
BT-37	Ml;OdWhVWyCjc4PhfS=>				MnvMdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohS2:wZnnycYF1d3K7IIPjdoVmdiCob4KgRnQuOzdiY3XscJM>	Mk\VQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
MG 63(6-TG R)	NGjI[oxyUFSVIHHzd4F6				MkjXdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohS2:wZnnycYF1d3K7IIPjdoVmdiCob4KgUWchPjNiKE[tWGchWiliY3XscJM>	MmnQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
Fibroblast cells	M1[xeZFJXFNiYYPzZZk>				NFzaUnVyUFSVIH;mJJBm\GmjdILpZ{Bk[W6lZYKgZ4VtdCCuaX7ld{B1dyCrZHXueIlngSCvdXz0bZBt\SCxcIDvdpR2dmm2aXXzJIZweiCmcoXnJJJmeHW{cH;zbY5oQiCFb37mbZJu[XSxcomgd4Nz\WWwIH\vdkBkd262cn;sJGhpKHerbHSgeJlx\SCoaXLyc4Jt[XO2IHPlcIx{	MlTLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
OHS-50	MmjsdWhVWyCjc4PhfS=>				NE\YWYVyUFSVIH;mJJBm\GmjdILpZ{Bk[W6lZYKgZ4VtdCCuaX7ld{B1dyCrZHXueIlngSCvdXz0bZBt\SCxcIDvdpR2dmm2aXXzJIZweiCmcoXnJJJmeHW{cH;zbY5oQiCFb37mbZJu[XSxcomgd4Nz\WWwIH\vdkBQUFNvNUCgZ4VtdHN?	NYrGfFJZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N\|UyOzlpPkK5OFM2OTN7PD;hQi=>
RD	MYTxTHRUKGG\|c3H5				MYLxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW\|IH\vdkBlenWpIILldJVzeG:\|aX7nPkBEd26oaYLtZZRwenlic3Py[YVvKG[xcjDSSEBk\Wyucx?=	NEP2fYg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
SJ-GBM2	MUTxTHRUKGG\|c3H5				MknCdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohWHKrbXHyfUB{[3KnZX6g[o9zKFOMLVfCUVIh[2WubIO=	NIXPR3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
SK-N-MC	MV\xTHRUKGG\|c3H5				MU\xTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW\|IH\vdkBlenWpIILldJVzeG:\|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhW0tvTj3NR{Bk\Wyucx?=	NIr4bmY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
NB-EBc1	NHP5b5RyUFSVIHHzd4F6				NWfj[Hd2eUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiUILpcYFzgSC\|Y4Ll[Y4h\m:{IF7CMWVD[zFiY3XscJM>	M4K3UFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6=
LAN-5	NYT6cJJ2eUiWUzDhd5NigQ>?				NUP4VGc5eUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiUILpcYFzgSC\|Y4Ll[Y4h\m:{IFzBUk02KGOnbHzz	NHHad\|U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
Rh18	M1nJN5FJXFNiYYPzZZk>				M2LnW5FJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KFC{aX3hdpkhe2O{ZXXuJIZweiCUaEG4JINmdGy\|	NEnIN3o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
NB1643	NIq1b2RyUFSVIHHzd4F6				Mne2dWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[\|ohS2:wZnnycYF1d3K7IIPjdoVmdiCob4KgUmIyPjR\|IHPlcIx{	NFf3bZI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
SK-N-MC	MY\xTHRUKGG\|c3H5				M4izTpFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KEOxbn\pdo1ifG:{eTDzZ5Jm\W5iZn;yJHNMNU5vTVOgZ4VtdHN?	MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR\|NUGzPUc,Ojl2M{WxN\|k9N2F-
SJ-GBM2	Ml7CdWhVWyCjc4PhfS=>				NUG2OY5FeUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiQ3;u[olzdWG2b4L5JJNkemWnbjDmc5IhW0pvR1LNNkBk\Wyucx?=	MnLKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
TC32	M{Kze5FJXFNiYYPzZZk>				M2CzVpFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KEOxbn\pdo1ifG:{eTDzZ5Jm\W5iZn;yJHREOzJiY3XscJM>	MkC0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN\|koRjJ7NEO1NVM6RC:jPh?=
Rh18	M{THbJFJXFNiYYPzZZk>				NHjVPXRyUFSVIH;mJJBm\GmjdILpZ{Bk[W6lZYKgZ4VtdCCuaX7ld{B1dyCrZHXueIlngSCvdXz0bZBt\SCxcIDvdpR2dmm2aXXzJIZweiCmcoXnJJJmeHW{cH;zbY5oQiCFb37mbZJu[XSxcomgd4Nz\WWwIH\vdkBTcDF6IHPlcIx{	M3jHNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6=
Saos-2	MknYdWhVWyCjc4PhfS=>				NUjMO\|M5eUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiQ3;u[olzdWG2b4L5JJNkemWnbjDmc5IhW2Gxcz2yJINmdGy\|	NHXjZXM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N\|UyOzl:L3G+
DU145	M2L1fGFxd3C2b4Ppd{Bie3OjeR?=	NYrU[JBjOTByIH7N	NVjE[W5oOjRiaILz		MX\JcoR2[3Srb36gc4Yh[XCxcITvd4l{KGmwIHj1cYFvKESXMUS1JINmdGy\|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKFCDUmCgZ4xm[X[jZ3WgZZQhOTByIH7NJIFnfGW{IEK0JIhzeyCkeTDpcY12dm:kbH;0eIlv\yCvZYToc4Q>	MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ6NUm0NUc,OjV4OEW5OFE9N2F-
HeLa	MXnGeY5kfGmxbjDhd5NigQ>?	MmfRNVAxKG6P			NXfacoNZUW6qaXLpeIlwdiCxZjDQUGsyKFSqckKxNEBxcG:\|cHjvdplt[XSrb36gbY4hcHWvYX6gTIVN[SClZXzsd{BifCBzMECgcm0h[nliaX3teY5w[myxdITpcochdWW2aH;k	M1fuTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nki1PVQyLz5{NU[4OVk1OTxxYU6=
DU145	NEfkZVNHfW6ldHnvckBie3OjeR?=	M1HFTVExOCCwTR?=			M{\0dmlvcGmkaYTpc44hd2ZiUFzLNUBxem:2ZXnuJIFk[3WvdXzheIlwdiCrbjDoeY1idiCGVUG0OUBk\WyuczDheEAyODBibl2gZpkhcW2vdX7vZoxwfHSrbnegcYV1cG:m	NEW3VpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[4OVk1OSd-MkW2PFU6PDF:L3G+
HeLa	M{Tz[mZ2dmO2aX;uJIF{e2G7	Mor0NVAxKG6P			NHHkNHJKdmirYnn0bY9vKG:oIGDMT\|EheHKxdHXpckBi[2O3bYXsZZRqd25iaX6gbJVu[W5iSHXMZUBk\WyuczDheEAyODBibl2gZpkhcW2vdX7vZoxwfHSrbnegcYV1cG:m	M3jMV\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nki1PVQyLz5{NU[4OVk1OTxxYU6=
HeLa	M3TFSGZ2dmO2aX;uJIF{e2G7	NWTJbVRmOTByIH7N	MVGxPEBpenN?		NHzIdJlKdmS3Y4Tpc44hd2ZibX;uc5BwdGG{IH3peI91cWNic4DpcoRt\XNiaX6gbJVu[W5iSHXMZUBk\WyuczDheEAyODBibl2gbY5kfWKjdHXkJIZweiBzODDodpMh[nliaX7kbZJm[3RiaX3teY5w\my3b4Lld4NmdmOnIH3pZ5Jwe2OxcIm=	NEPibYw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[4OVk1OSd-MkW2PFU6PDF:L3G+
HeLa	MmTwRZBweHSxc3nzJIF{e2G7	NE\MTW4yODBibl2=	Mnv3NlQhcHK\|		M4HsZmlv\HWldHnvckBw\iCjcH;weI9{cXNiaX6gbJVu[W5iSHXMZUBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCSQWLQJINt\WG4YXflJIF1KDFyMDDuUUBi\nSncjCyOEBpenNiYomgbY1ufW6xYnzveJRqdmdibXX0bI9l	M1TYfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nki1PVQyLz5{NU[4OVk1OTxxYU6=
PC3	NF7PN2pHfW6ldHnvckBie3OjeR?=	MXixNFAhdk1?	NIPOUFIyQCCqcoO=		M{jrNGlv\HWldHnvckBw\iCvb37vdI9t[XJibXn0c5Rq[yC\|cHnu[IxmeyCrbjDoeY1idiCSQ{OgZ4VtdHNiYYSgNVAxKG6PIHnuZ5Vj[XSnZDDmc5IhOThiaILzJIJ6KGmwZHny[YN1KGmvbYXuc4ZtfW:{ZYPj[Y5k\SCvaXPyc5Nkd3C7	Moi0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV4OEW5OFEoRjJ3Nki1PVQyRC:jPh?=
DU145	NH7TOFRHfW6ldHnvckBie3OjeR?=	NUSzcVN3OTByIH7N			NVLQVnNXUW6qaXLpeIlwdiCxZjDQUGsyKFSqckKxNEBxcG:\|cHjvdplt[XSrb36gbY4hcHWvYX6gSHUyPDViY3XscJMh[XRiMUCwJI5OKGK7IHntcZVvd2Kub4T0bY5oKG2ndHjv[C=>	M3rUfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nki1PVQyLz5{NU[4OVk1OTxxYU6=

... Click to View More Cell Line Experimental Data

Assay

Methods	Test Index	PMID
Western blot	pro-caspase-8 / cleaved caspase-8 / cleaved caspase-3 / cleaved caspase-9; PubMed: 27699933 Cancer Sci PLKi‐induced caspase activation. HeLa cells were treated with BI 2536 (10 nmol/L), BI 6727 (68 nmol/L), or GSK461364 (11 nmol/L), and HCT 116 cells were treated with BI 2536 (20 nmol/L), BI 6727 (70 nmol/L), or GSK461364 (12 nmol/L) for 48 h. The levels of cleaved caspase (CASP)‐3, ‐8, and ‐9 were examined by Western blot analysis. p-HH3 / PARP / Myc / p-Myc; PubMed: 24771642 Clin Cancer Res Western blotting showing more mitotic arrested (shown by phospho-histone H3) and apoptotic (shown by PARP) cells as well as lower MYC levels in LNCaP-Pim1 cells after BI 2536 treatment compared with LNCaP-Neo cells. The difference is obvious at lower dose of BI 2536 (10 nM). Both total MYC expression and phosphor-MYC levels were lower in Pim1 cells than Neo cells after BI 2536 treatment. pMEK / MEK / pERK / ERK / pRSK1 / RSK1; PubMed: 28430578 Oncotarget (A) and (B) Western blot analysis of the expression and activation of components of the MEK-ERK-RSK1 pathway in MKN45 and MKN74 cancer cells treated with BI 2536 and BI 6727 for 24 and 48 hours, respectively. pPlk1 / Plk1 / pMyt1; PubMed: 28430578 Oncotarget (A) and (B) Western blot analysis of the expression and phosphorylation of Plk1, and phosphorylation of Myt1 in the CSC-like and cancer cells after treatment with BI 2536 and BI 6727 for 24 and 48 hours, respectively. Aurora B / pAurora B / pAurora C / pH3 / Cyclin B1 / Securin / pBcl-XL / MPM2; PubMed: 25169932 Mol Oncol Western blot analysis of cells treated for 24 h with the indicated inhibitor concentrations. Cell lysates were immunoblotted for Plk1, Phospho-Aurora B (T232)/Aurora C (T198), Aurora B, histone H3 phosphorylated at S10 (pH3), Cdk1, Cyclin B1, Securin, Phospho-Bcl-XL, Induced myeloid leukemia cell differentiation protein Mcl-1, MPM-2 and β-Actin. Left (Hela cells); Right (HUVEC)	27699933 24771642 28430578 25169932
Immunofluorescence	p-H2AX / propidium iodide; PubMed: 22309939 Breast Cancer Res Apoptotic images of the cells after BI 2536 treatment, as revealed by HCS (high-content screening) instrument (×10) with phospho-H2AX antibody or PI (propidium iodide) intake. Pericentrin / α-tubulin; PubMed: 21772266 Nat Commun MEFs were labelled using Plk1, pericentrin and α-tubulin antibodies and 4,6-diamidino-2-phenylindole for the analysis by immunofluorescence microscopy. Representative examples of BI 2536-treated and control MEFs are depicted. Scale bar, 5 μm.	22309939 21772266
Growth inhibition assay	Cell viability; PubMed: 21772266 Nat Commun Proliferative activity of MEFs at different BI 2536 concentrations (25–250 nM; means±s.d., n=3, for each concentration). P<0.05, P<0.01, **P<0.001, Student's t-test, unpaired and two-tailed.	21772266

In vivo

BI 2536 given i.v. once or twice per week is highly efficacious in diverse xenograft models with acceptable tolerability by inhibiting cell proliferation through a mitotic arrest, and subsequently induction of tumor-cell death. Administration of BI 2536 at 50 mg/kg once or twice per week significantly inhibits growth of HCT 116 xenografts with T/C of 15% and 0.3%, respectively. BI 2536 treatment twice-weekly also leads to excellent tumor-growth in BxPC-3 and A549 models with T/C of 5% and 14%, respectively. ^[1]

Protocol

Kinase Assay: ^[1]	- Collapse Plk1 in vitro kinase assay: Recombinant human Plk1 (residues 1-603) is expressed as N-terminal, GST-tagged fusion protein with a baculoviral expression system and purified by affinity chromatography with Glutathione-agarose. Enzyme activity assays for Plk1 are performed in the presence of serially diluted BI 2536 with 20 ng of recombinant kinase and 10 μg casein from bovine milk as the substrate. Kinase reactions are performed in a final volume of 60 μL for 45 minutes at 30 °C (15 mM MgCl₂, 25 mM MOPS [pH 7.0], 1 mM DTT, 1% DMSO, 7.5 mM ATP, 0.3 μCi γ-³³P-ATP). Reactions are terminated by the addition of 125 μL of ice-cold 5% TCA. After transfer of the precipitates to Multi-Screen mixed ester cellulose filter plates, plates are washed with 1% TCA and quantified radiometrically. Dose-response curve is used for calculating IC50 value.
Cell Research: ^[1]	- Collapse Cell lines: HeLa, A43, SKOV-3, HT-29, K562, A549, Saos-2, MCF7, HCT116, COLO 205, Hep G2, Raji and PC-3 cells, etc. Concentrations: Dissolved in DMSO, final concentrations ~1 μM Incubation Time: 24 and 72 hours Method: Cells are exposed to various concentrations of BI 2536 for 24, and 72 hours. Cell growth is assessed by the measurement of Alamar Blue dye conversion in a fluorescence spectrophotometer. For determining the DNA content of the cultures, cell suspensions are fixed in 80% ethanol, treated for 5 minutes with 0.25% Triton X-100 in PBS, and incubated with 0.1% RNase and 10 μg/mL propidium iodide (PI) in PBS for 20 minutes at RT. Cell-cycle profiles are determined by flow cytometric analysis. (Only for Reference)
Animal Research: ^[1]	- Collapse Animal Models: Female BomTac:NMRI-Foxn1^nu mice injected subcutaneously with HCT 116, NCI-H460, or A549 cells Dosages: ~50 mg/kg Administration: Injection i.v. once or twice per week (Only for Reference)

References

Solubility (25°C)

In vitro	Ethanol	100 mg/mL (191.69 mM)
	DMSO	21 mg/mL (40.25 mM)
	Water	Insoluble
In vivo	Add solvents to the product individually and in order(Data is from Selleck tests instead of citations): 30% PEG 400+0.5% Tween 80+5% Propylene glycol For best results, use promptly after mixing.	15mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download BI 2536 SDF

Molecular Weight	521.66
Formula	C₂₈H₃₉N₇O₃
CAS No.	755038-02-9
Storage	3 years-20°C powder 2 years-80°C in solvent
Synonyms	N/A
Smiles	CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage

mg/kg

Average weight of animals

Dosing volume per animal

Number of animals

Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)

% DMSO+ % + % Tween 80+ % ddH₂O

Calculate Reset

Calculation results:

Working concentration： mg/ml；

Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH₂O，mix and clarify.

Note：1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2020-01-06)

NCT Number	Recruitment	interventions	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT02215044	Terminated	Drug: BI 2536 intravenous\|Drug: Gemcitabine intravenous	Pancreatic Neoplasms	Boehringer Ingelheim	June 2007	Phase 1
NCT02211833	Completed	Drug: BI 2536\|Drug: Pemetrexed	Carcinoma Non-Small-Cell Lung	Boehringer Ingelheim	October 2006	Phase 1
NCT00701766	Completed	Drug: BI 2536	Leukemia Myeloid Acute	Boehringer Ingelheim	October 2006	Phase 2
NCT00706498	Completed	Drug: BI 2536	Prostatic Neoplasms	Boehringer Ingelheim	September 2006	Phase 2
NCT00376623	Completed	Drug: BI 2536	Carcinoma Non-Small-Cell Lung	Boehringer Ingelheim	July 2006	Phase 2
NCT02211872	Completed	Drug: BI 2536 BS intravenous	Neoplasms	Boehringer Ingelheim	August 2004	Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

Frequently Asked Questions

Question 1:
We need to use BI 2536 in preclinical studies using mice, how to formulate the inhibitor for this in vivo study?
Answer:
For in vivo study, DMSO should not be more than 5% because the toxicity. You can formulated BI2536 in hydrochloric acid (0.1 N), and diluted with 0.9% NaCl for animal study according to the reference :( Supplemental Data) http://linkinghub.elsevier.com/retrieve/pii/S0960-9822(06)02671-6

PLK Signaling Pathway Map

PLK Inhibitors with Unique Features

Selective Plk Inhibitors

GSK461364 : Plk1-selective, K_i=2.2 nM.
Plk Inhibitor in Clinical Trial

Rigosertib (ON-01910) : Phase III for Myelo Dysplastic Syndrome (MDS).
Newest Plk Inhibitor

Ro3280 ^New : Potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
Calssic Plk Inhibitor

Volasertib (BI 6727) : Highly potent Plk1 inhibitor with IC50 of 0.87 nM and in phase II trials.

Related PLK Products

SBE 13 HCl ^New

SBE 13 HCl is a potent and selective PLK1 inhibitor with IC50 of 200 pM, >4000-fold selectivity over Aurora A kinase, Plk2 and Plk3.
Ro-3306 ^New

RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with K_i of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.
CCG-1423 ^New

CCG-1423 is a specific RhoA pathway inhibitor, which inhibits SRF-mediated transcription.
Rigosertib (ON-01910)

Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.
HMN-214

HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation of Plk1.
GSK461364

GSK461364 inhibits purified Plk1 with K_i of 2.2 nM in a cell-free assay. It is more than 1000-fold selective against Plk2/3. Phase 1.

Features:Demonstrates >390-fold selectivity for Plk1 relative to Plk2 and Plk3.
Volasertib (BI 6727)

Volasertib (BI 6727) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. Volasertib induces cell cycle arrest and apoptosis in various cancer cells. Phase 3.

Features:A high volume of distribution, indicating good tissue penetration, and a long terminal half-life.
MLN0905

MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM.
Ro3280

RO3280 (Ro5203280) is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.

Features:A selective PLK1 inhibitor. Demonstrates greater potency than BI2536. Potential use in nasopharyngeal carcinomas.
Onvansertib (NMS-P937)

Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.

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BI 2536