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PI3K/Akt/mTOR

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Cat.No. Product Name Information Product Use Citations Product Validations
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
Nature, 2025, 10.1038/s41586-025-09203-8
Haematologica, 2025, 110(8):1822-1833
Cell Commun Signal, 2025, 23(1):274
Verified customer review of LB-100
S8774 DT-061 (SMAP) DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
J Asthma Allergy, 2025, 18:1505-1522
Sci Adv, 2025, 11(34):eadv6937
Cell Rep, 2024, 43(4):114054
S0308 AMZ30 AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. This compound reduces the demethylated form of PP2A in living cells.
S3861 Sodium Demethylcantharidate Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.
iScience, 2024, 27(10):110862
S8248 IQ-1 IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
Haematologica, 2022, 10.3324/haematol.2022.280760
Neoplasia, 2020, 23(1):1-11
Cell Mol Life Sci, 2019, 76(14):2817-2832
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
Nature, 2025, 10.1038/s41586-025-09203-8
Haematologica, 2025, 110(8):1822-1833
Cell Commun Signal, 2025, 23(1):274
 Verified customer review of LB-100
S0308 AMZ30 AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. This compound reduces the demethylated form of PP2A in living cells.
S3861 Sodium Demethylcantharidate Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.
iScience, 2024, 27(10):110862
S8248 IQ-1 IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
Haematologica, 2022, 10.3324/haematol.2022.280760
Neoplasia, 2020, 23(1):1-11
Cell Mol Life Sci, 2019, 76(14):2817-2832
S8774 DT-061 (SMAP) DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
J Asthma Allergy, 2025, 18:1505-1522
Sci Adv, 2025, 11(34):eadv6937
Cell Rep, 2024, 43(4):114054