PP2A
Inhibitory Selectivity
PP2A Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0308New |
AMZ30AMZ30 is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells. |
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| S7537 |
LB-100LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. |
LB-100 induced HDAC2 S394 phosphorylation.
|
|
| S8248 |
IQ-1IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction. |
||
| S8774New |
DT-061(SMAP)DT-061(SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0308New |
AMZ30AMZ30 is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells. |
||
| S7537 |
LB-100LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. |
LB-100 induced HDAC2 S394 phosphorylation.
|
|
| S8248 |
IQ-1IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S8774New |
DT-061(SMAP)DT-061(SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively. |
