PP2A

PP2A Products

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  • PP2A Inhibitors (4)
  • PP2A Activator (1)
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Catalog No. Product Name Information Product Use Citations Product Validations
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
Cell Death Dis, 2024, 15(2):121
Blood Cancer J, 2023, 13(1):106
Cell Death Dis, 2023, 14(2):114
S8774 DT-061 (SMAP) DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
Nat Commun, 2023, 10.1038/s41467-023-42978-w
Cell Death Dis, 2023, 14(12):793
Cell Rep, 2023, 42(6):112542
S8248 IQ-1 IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
Haematologica, 2022, 10.3324/haematol.2022.280760
Neoplasia, 2020, 23(1):1-11
Cell Mol Life Sci, 2019, 76(14):2817-2832
S0308 AMZ30 AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
S3861 Sodium Demethylcantharidate Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.
S7537 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
Cell Death Dis, 2024, 15(2):121
Blood Cancer J, 2023, 13(1):106
Cell Death Dis, 2023, 14(2):114
S8248 IQ-1 IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.
Haematologica, 2022, 10.3324/haematol.2022.280760
Neoplasia, 2020, 23(1):1-11
Cell Mol Life Sci, 2019, 76(14):2817-2832
S0308 AMZ30 AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
S3861 Sodium Demethylcantharidate Demethylcantharidin (norcantharidin) is a synthetic analogue of cantharidin and has potent antitumor activity.
S8774 DT-061 (SMAP) DT-061 (SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively.
Nat Commun, 2023, 10.1038/s41467-023-42978-w
Cell Death Dis, 2023, 14(12):793
Cell Rep, 2023, 42(6):112542

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