PP2A
Inhibitory Selectivity
PP2A Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0308New |
AMZ30AMZ30 is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells. |
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| S7537 |
LB-100LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. |
LB-100 induced HDAC2 S394 phosphorylation.
|
|
| S8248 |
IQ-1IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction. |
||
| S9695New |
iHAP1iHAP1 is an activator of Protein phosphatase 2A (PP2A) enzymes. The PP2A complex activated by iHAP1 dephosphorylates the MYBL2 transcription factor on Ser241, causing irreversible arrest of leukemia and other cancer cells in prometaphase. |
||
| S8774 |
DT-061(SMAP)DT-061(SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0308New |
AMZ30AMZ30 is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells. |
||
| S7537 |
LB-100LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. |
LB-100 induced HDAC2 S394 phosphorylation.
|
|
| S8248 |
IQ-1IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S9695New |
iHAP1iHAP1 is an activator of Protein phosphatase 2A (PP2A) enzymes. The PP2A complex activated by iHAP1 dephosphorylates the MYBL2 transcription factor on Ser241, causing irreversible arrest of leukemia and other cancer cells in prometaphase. |
||
| S8774 |
DT-061(SMAP)DT-061(SMAP) is a bioavailable PP2A activator. It decreases cell viability in HCC827 and HCC3255 cell lines, with IC50 values of 14.3 μM and 12.4 μM respectively. |
