BMI-1

Inhibitory Selectivity

BMI-1 Products

Catalog No. Information Product Use Citations Product Validations
S7372

PTC-209

PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).

S5315

PRT4165

PRT4165 is a Bmi1/Ring1A inhibitor with an IC50 of 3.9 µM in the cell-free assay and also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro.

S7539

PTC-209 HBr

PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).

S8662

PTC-028

PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification.

Catalog No. Information Product Use Citations Product Validations
S7372

PTC-209

PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).

S5315

PRT4165

PRT4165 is a Bmi1/Ring1A inhibitor with an IC50 of 3.9 µM in the cell-free assay and also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro.

S7539

PTC-209 HBr

PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).

S8662

PTC-028

PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification.

Tags: BMI-1 inhibitor | BMI-1 modulator | BMI-1 chemical