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Nur77

Other Cell Cycle Related Inhibitors

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Cat.No. Product Name Information Product Use Citations Product Validations
S6674 Cytosporone B (Csn-B) Cytosporone B is a naturally occurring agonist for nuclear orphan receptor Nur77(NR4A1) with an EC50 of 0.278nM.
Exp Cell Res, 2026, 454(2):114824
Exp Mol Med, 2025, 57(4):804-819
J Adv Res, 2025, S2090-1232(25)00582-X
S0149 C-DIM5 C-DIM5 (DIM-C-pPhOCH3) is an agonist of Nur77 (Nerve growth factor-induced Bα (NGFI-Bα)/nuclear receptor 4A1 (NR4A1)) which is an orphan nuclear receptor. This compound decreases survival and induces apoptosis in RKO colon cancer cells.
STAR Protoc, 2025, 6(1):103593
Cell Rep Med, 2024, S2666-3791(24)00234-9
Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8
S6799 DIM-C-pPhOH DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist. This compound inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. It reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.
J Adv Res, 2025, S2090-1232(25)00582-X
Cell Rep, 2024, 43(2):113746
Mol Psychiatry, 2022, 10.1038/s41380-022-01497-8
S6785 DIM-C-pPhCO2Me DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist with antineoplastic activity.