Nur77

Inhibitory Selectivity

Nur77 Products

Catalog No. Information Product Use Citations Product Validations
S6785

DIM-C-pPhCO2Me

DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist with antineoplastic activity.
S6799

DIM-C-pPhOH

DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.
S6674

Cytosporone B

Cytosporone B is a naturally occurring agonist for nuclear orphan receptor Nur77(NR4A1) with an EC50 of 0.278nM.
Signal Transduct Target Ther, 2021, 6(1):133
Cell Physiol Biochem, 2018, 46(3):1078-1090
J Pineal Res, 2018, 64(1)
S0149

C-DIM5

C-DIM5 (DIM-C-pPhOCH3) is an agonist of Nur77 (Nerve growth factor-induced Bα (NGFI-Bα)/nuclear receptor 4A1 (NR4A1)) which is an orphan nuclear receptor. C-DIM5 (DIM-C-pPhOCH3) decreases survival and induces apoptosis in RKO colon cancer cells.
Catalog No. Information Product Use Citations Product Validations
S6785

DIM-C-pPhCO2Me

DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist with antineoplastic activity.
S6799

DIM-C-pPhOH

DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1)(Nur77) antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.
Catalog No. Information Product Use Citations Product Validations
S6674

Cytosporone B

Cytosporone B is a naturally occurring agonist for nuclear orphan receptor Nur77(NR4A1) with an EC50 of 0.278nM.
Signal Transduct Target Ther, 2021, 6(1):133
Cell Physiol Biochem, 2018, 46(3):1078-1090
J Pineal Res, 2018, 64(1)
S0149

C-DIM5

C-DIM5 (DIM-C-pPhOCH3) is an agonist of Nur77 (Nerve growth factor-induced Bα (NGFI-Bα)/nuclear receptor 4A1 (NR4A1)) which is an orphan nuclear receptor. C-DIM5 (DIM-C-pPhOCH3) decreases survival and induces apoptosis in RKO colon cancer cells.