All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
F0378 FoxM1 Rabbit mAb Sep 04 2024
F0494 Phospho-β-Catenin (Ser 552) Rabbit mAb Sep 04 2024
F0497 Phospho-GSK-3α/β (Ser 21/9) Rabbit mAb Glycogen synthase kinase-3 alpha, GSK-3 alpha, Glycogen synthase kinase-3 beta, GSK-3α, GSK-3 beta, GSK-3β, GSK3A, GSK3B, GSK3, Serine/threonine-protein kinase GSK3B Sep 04 2024
F0527 Ubiquitin (linkage-specific Lys 48) Rabbit mAb K48-linkage Specific Polyubiquitin,Ubiquitin (linkage-specific K48) Sep 04 2024
F0157 Phospho-Stat3 (Tyr705) Rabbit mAb Phospho-Stat3 (Tyr705),p-Stat3,STAT3 (phospho Y705) Sep 04 2024
F0156 Phospho-SAPK/JNK (Thr183/Tyr185) Rabbit mAb Phospho-SAPK/JNK (Thr183/Tyr185),p-JNK Sep 04 2024
F0247 Phospho-IGF-I Receptor (Tyr1135/1136)/Insulin Receptor (Tyr1150/1151) Rabbit mAb Insulin-like growth factor 1 receptor, CD221, IGF1R, Insulin receptor, CD220, IR Sep 04 2024
F0179 BACE Rabbit mAb BACE,BACE1 Sep 04 2024
F0353 Phospho-c-Raf (Ser338) Rabbit mAb Sep 04 2024
F0400 Phospho-NF-κB p105 (Ser 932) Rabbit mAb Sep 04 2024
F0452 Progesterone Receptor A/B Rabbit mAb Progesterone Receptor A/B Sep 04 2024
F0634 Jagged1 Rabbit mAb Sep 04 2024
E1508 APG-2449 APG-2449 is an orally active inhibitor of ALK/ROS1/FAK. APG-2449 exerts potent and durable antitumor activity in human non-small-cell lung cancer (NSCLC) and ovarian tumor models. Sep 04 2024
E4662 CK-586 CK-586(CK-4021586) is an inhibitor of cardiac myosin used to treat obstructive hypertrophic cardiomyopathy (oHCM). It effectively reduces left ventricular outflow tract obstruction (LVOTO) in a dose-dependent manner. Sep 03 2024
E4695 OPB-171775 OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12). This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST). Sep 03 2024
E4679 Bleximenib oxalate Bleximenib oxalate(Menin-MLL inhibitor 24 oxalate) is an inhibitor of menin-mixed-lineage leukemia 1 (menin-MLL) . It can be used for the research of cancer. Sep 03 2024
E4659 Pyr3 Pyr3 is a selective and potent inhibitor of transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner with the IC50 value of 0.7 μM. It holds potential for treating TRPC3-related diseases like cardiac hypertrophy. Sep 03 2024
E1556 GSK-3484862 GSK-3484862 is a non-covalent, potent and selective inhibitor of DNMT1 with an IC50 of 0.23 μM. It demonstrates efficacy in acute myeloid leukemia. Sep 03 2024
E4660 TAC(TERT activator compound) TAC(TERT activator compound) is an activator of TERT, that upregulates TERT transcription via the MEK/ERK/AP-1 cascade. It enhances telomere synthesis, reduces aging markers, inflammation, and senescence, and preserves brain function, highlighting TERT's potential in combating aging and related diseases. Sep 03 2024
E4624 Tradipitant Tradipitant(VLY-686, LY686017) is the 2nd generation antagonist of neurokinin-1 (NK-1). It exhibits potential for treating chemotherapy-induced nausea, depression, alcoholism, social anxiety disorder, and for developing imaging ligands. Sep 03 2024