HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E8072 Sagittatoside A Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii). Dec 20 2024
E7818 INCA-6 INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the  calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling. Dec 20 2024
E8073 Sagittatoside B Sagittatoside B is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii). Dec 20 2024
E7563 1-Methylguanosine 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker. Dec 20 2024
E7819 TTA-A2 TTA-A2 is a potent and selective antagonist of T-type calcium channel with an IC50 of 9.4 nM, and reduced PXR activation, promoting slow-wave sleep in mice. It shows strong efficacy in rodent models of epilepsy and sleep, making it a valuable preclinical tool for the research of a variety of human neurological diseases. Dec 20 2024
E8074 Oxazine 1 perchlorate Oxazine 1 perchlorate is a symmetric cationic dye (λex=653 nm, λem=666 nm). Dec 20 2024
E7564 3-Methylcytidine 3-Methylcytidine, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer. Dec 20 2024
E7820 RAGE antagonist peptide RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities. Dec 20 2024
E8075 Ucf-101 Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect. Dec 20 2024
E7565 360A iodide 360A iodide is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay. Dec 20 2024
E7821 BODIPY 505/515 BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 505/515 nm. Dec 20 2024
E4608 4-Hydroperoxy cyclophosphamide 4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases. Dec 19 2024
E7010 (±)-BI-D (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site. Dec 19 2024
E7214 Sabinene Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways. Dec 19 2024
E4998 Polyinosinic-polycytidylic acid sodium Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic double-stranded RNA (dsRNA) analogue that activates the MDA-5 receptor in the cytoplasm and TLR3 in endosomal compartments. This activation promotes the production of type I interferons and induces apoptosis in cancer cells, particularly those that lack protective anti-apoptotic mechanisms like Bcl-xL. Dec 19 2024
E7437 Phenol Red Phenol red (Phenolsulfonephthalein) is a pH indicator dye commonly used in cell culture media, where it changes color from yellow to red based on pH levels. It also participates in redox reactions, particularly in the presence of enzymes like myeloperoxidase, influencing cellular oxidative states without directly causing significant toxicity. Dec 19 2024
E7011 1,3-Diphenylisobenzofuran 1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals. Dec 19 2024
E7216 Isoquinoline Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities. Dec 19 2024
E7438 Desmethylglycitein Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes. Dec 19 2024
E7012 Conduritol B epoxide Conduritol B epoxide is an irreversible covalently bound inhibitor of Gcase. It can be used in the research of Neuronopathic Gaucher disease (nGD). Dec 19 2024