All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
F0433 HER3/ErbB3 Rabbit mAb ErbB3,ErbB3 / HER3,ErbB3/HER3,erbB-3/HER-3,HER3/ErbB3 Jul 15 2024
F0455 Synapsin-1 Rabbit mAb Synapsin I,Synapsin-1 Jul 15 2024
F0500 Phospho-RIP (Ser166) Rabbit mAb Jul 15 2024
F0971 EB1 mAb EB1,EB-1,MAPRE1/EB1 Jul 15 2024
F0528 Ubiquitin (linkage-specific Lys 63) Rabbit mAb K63-linkage Specific Polyubiquitin,Ubiquitin (linkage-specific K63),Ub-K63 Jul 15 2024
F0729 FIP200 Rabbit mAb Jul 15 2024
F0286 LC3A Rabbit mAb LC3,LC3A,MAP1LC3A Jul 15 2024
F0464 Phospho-GSK-3 (Ser21) Rabbit mAb GSK3 alpha (phospho S21),Phospho-GSK-3α (Ser21) Jul 15 2024
F1070 CD14 Rat mAb Jul 15 2024
E1966 VVD-214 VVD-214 (RO7589831, VVD-133214) is a synthetic allosteric inhibitor of WRN helicase. VVD-214 binds irreversibly to cysteine 727 on WRN, suppressing ATP hydrolysis and helicase activity. VVD-214 exhibits potent efficacy in inducing double-stranded DNA breaks, nuclear enlargement, and cellular apoptosis in cancers with high microsatellite instability (MSI). Jul 15 2024
E1970 BAL-0028 BAL-0028 (Compound 3), which belongs to the indazole class is an inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds tightly to the NACHT domain of NLRP3, with KD values ranging from 104 to 123 nM. BAL-0028 also exhibits anti-inflammatory activity. Jul 15 2024
E1186 Tenapanor Tenapanor (AZD1722, RDX5791) is a potent and orally active inhibitor of sodium/hydrogen exchanger isoform 3 (NHE3). It exhibits an IC50 of 2 and 6 nM in human and mouse ileum monolayers, respectively. Tenapanor reduces intestinal phosphate absorption predominantly by reducing passive paracellular phosphate flux. Jul 15 2024
E4821 Simvastatin acid (ammonium) Simvastatin acid (Tenivastatin) ammonium is a potent inhibitor of HMG-CoA reductase (HMGCR). Simvastatin acid ammonium also decreases Indoxyl sulfate-induced reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium regulates the expression of OATP3A1 in cardiomyocytes. Jul 15 2024
E4820 Sulbactam pivoxil Sulbactam pivoxil (CP 47904), a proagent of sulbactam, is an inhibitor of β-lactamase. Sulbactam pivoxil provides higher absorption than its parent compound and achieves high serum levels following oral administration. Jul 15 2024
E4818 Pemetrexed (disodium heptahydrate) Pemetrexed (disodium heptahydrate) is a folate antimetabolite that inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase. It also induces apoptosis and cell-cycle arrest in non-small-cell lung cancer carrying an EGFR exon 19 deletion. Jul 14 2024
F1454 UHRF1 Rabbit mAb Jul 11 2024
F1456 Cool2/αPix Rabbit mAb Jul 11 2024
F1343 Munc18-1 Rabbit mAb Jul 11 2024
F1551 NDUFA9 mAb Jul 11 2024
F0125 Bcl-2 Rabbit mAb Bcl2,Bcl-2 Jul 11 2024