HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E7804 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity. Dec 20 2024
E8059 VH032-cyclopropane-F VH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4. Dec 20 2024
E7549 Halofantrine hydrochloride Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound. Dec 20 2024
E7805 cis-Epoxysuccinic acid cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 µM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system. Dec 20 2024
E8060 N-Acetylprocainamide N-Acetylprocainamide is a class III antiarrhythmic, which blocks K+ channels. Dec 20 2024
E7550 Filanesib Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity. Dec 20 2024
E7806 Thyrotropin-Releasing Hormone (TRH), Free Acid Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) is a physiological metabolite of Thyrotropin-Releasing Hormone. Dec 20 2024
E8061 5'-Deoxyadenosine 5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. 5'-Deoxyadenosine shows anti-orthopoxvirus activity. Dec 20 2024
E7551 MK-5046 MK-5046 is a potent, selective and orally active Bombesin receptor subtype-3 (BRS-3) allosteric agonist with an IC50 and an EC50 value of 27 and 25 nM for hBRS-3, respectively. MK-5046 inhibits food intake and reduces body weight of diet-induced obese (DIO) mouse models. MK-5046 can be used for the research of obesity. Dec 20 2024
E7807 BETP BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively. Dec 20 2024
E8062 D-64131 D-64131 is an orally active tubulin inhibitor, with an IC50 of 0.53 μM for tubulin polymerization. D-64131 has antimitotic activity. D-64131 can be used for cancer research. Dec 20 2024
E7552 Reparixin L-lysine salt Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation. Dec 20 2024
E7808 PSB-603 PSB-603 is a potent and highly selective A2B adenosine receptor antagonist exhibiting a Ki value of 0.553 nM and virtually no affinity for the human and rat A1 and A2A and the human A3 receptors up to a concentration of 10 μM. Dec 20 2024
E8063 Acumapimod Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α. Dec 20 2024
E5773 Gypenoside L Gypenoside L, is a saponin from Gynostemma pentaphyllum, increases SA-β-galactosidase activity, enhances senescence-associated cytokine production, inhibits proliferation and LPS-induced nitric oxide (NO) production, induces S-phase arrest, and activates p21, p27, p38, ERK MAPK, and NF-κB pathways to promote senescence. Dec 20 2024
E7553 DMP 777 DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor. Dec 20 2024
E7809 Acridine Orange base Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays. Dec 20 2024
E8064 Pseudomonas quinolone signal Pseudomonas Quinolone Signal (Compound C), a signaling molecule produced by Pseudomonas aeruginosa, can activate lasB. Pseudomonas Quinolone Signal can be used in the study of virulence regulation in Pseudomonas aeruginosa. Dec 20 2024
E7554 Bay 65-1942 hydrochloride Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor. Dec 20 2024
E7810 Eicosadienoic acid Eicosadienoic acid (Eicosa-11Z,14Z-dienoic Acid) is a polyunsaturated fatty acid that is metabolized to stearidonic acid (SCA) in macrophages, altering cellular phospholipid composition. It alters the inflammatory response to lipopolysaccharide (LPS) by decreasing nitric oxide (NO) production and increasing prostaglandin E2 (PGE2) and TNF-α levels. Dec 20 2024