All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E8255 Lamotrigine-13C,d3 Lamotrigine-13C,d3 is the deuterated form of lamotrigine. Lamotrigine is a new anticonvulsant agent. Mar 26 2025
E8256 SiroliMus-D3/ RapaMycin-D3 SiroliMus-D3/ RapaMycin-D3 is a deuterated derivative of sirolimus. Sirolimus is a potent and specific mTOR inhibitor. Mar 26 2025
E8257 Cortisol-d5 Cortisol-D5 is the deuterated form of hydrocortisone. Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal glands. Mar 26 2025
E8258 Aldosterone-d7 Aldosterone-d7 is the deuterated form of aldosterone. Aldosterone is the primary mineralocorticoid. Mar 26 2025
E8259 progesterone-d9 Progesterone-d9 is a deuterated form of progesterone.Progesterone is an endogenous steroid hormone that is involved in regulating the menstrual cycle, pregnancy, and embryonic development in humans and other species. Mar 26 2025
E8260 Pregnenolone-d4 Pregnenolone-d4 is a deuterated form of Pregnenolone.Pregnenolone is an endogenous steroid hormone. Mar 26 2025
E8261 1,2-dichlorobenzene-d4 1,2-dichlorobenzene-d4 is the deuterated product of 12-dichloro-benzene. 1,2-dichlorobenzene is mainly used in the synthesis of phthalic anhydride, pesticides and long-acting sulfonamide drugs. Mar 26 2025
E8262 4-Bromofluorobenzene-d4 4-Bromofluorobenzene-d4 is the deuterated product of 1-Bromo-4-fluorobenzene. 1-Bromo-4-fluorobenzene is an organic halogenated aromatic compound, mainly used in the synthesis of pharmaceutical intermediates or functional materials. Mar 26 2025
E8263 anthracene-d10 Anthracene-d10 is the deuterated derivative of anthracene. Anthracene is a tricyclic fused aromatic hydrocarbon mainly used in the synthesis of anthraquinone compounds (such as anti-tumor drug precursors). Mar 26 2025
E8264 naphthalene-d8 Naphthalene-d8 is the deuterated form of naphthalene. Naphthalene is an aromatic hydrocarbon compound that is mainly used as an industrial raw material for the synthesis of phthalic anhydride, pesticides, and plant growth regulators. Mar 26 2025
E8265 Carbazole D8 Carbazole D8 is the deuterated derivative of 9H-carbazole. 9H-Carbazole is a tricyclic aromatic heterocyclic compound that can inhibit the synthesis of new DNA or RNA by binding to DNA and has potential antitumor or antibacterial activity. Mar 26 2025
E8266 4,4'-dibromobiphenyl-d8 4,4'-dibromobiphenyl-d8 is the deuterated derivative of 4,4'-Dibromobiphenyl. 4,4'-Dibromobiphenyl is an important intermediate in polymer materials and the electronics industry, and is used in polymer synthesis as a flame retardant or crosslinking agent. Mar 26 2025
E8267 9-bromoanthracene-d9 9-Bromoanthracene-d9 is the deuterated derivative of 9-Bromoanthracene. 9-Bromoanthracene is an organic synthesis intermediate, commonly used in the preparation of polycyclic aromatic hydrocarbon derivatives. Mar 26 2025
E8268 1-bromonaphthalene-d7 1-Bronaphthalene-d7 is the deuterated form of 1-Bromonaphthalene. 1-Bromonaphthalene is a biochemical reagent that can be used as a biomaterial or organic compound related to life science research. Mar 26 2025
E5824 Lenumlostat Lenumlostat (PAT-1251, GB2064) is a potent, selective, and orally available inhibitor of lysyl oxidase-like 2 (LOXL2). It exhibits greater selectivity for LOXL2 over other family members, with IC50 of 0.71 μM for hLOXL2 and 1.17 μM for hLOXL3. It also possesses anti-fibrotic properties. Mar 26 2025
E4726 NDI-101150 NDI-101150 is a potent HPK1 (MAP4K1) inhibitor that selectively activates immune cells such as T cells, B cells, and dendritic cells. It significantly inhibits tumor growth and induces complete tumor regression in the EMT-6 mouse model. Mar 26 2025
E4756 MCB-22-174 MCB-22-174 is a potent agonist of Piezo1, with an EC50 value of 6.28 µM. It activates the Ca2+-related extracellular signal-related kinases and calcium–calmodulin (CaM)-dependent protein kinase II (CaMKII) pathway and promotes mesenchymal stem cells osteoblastic differentiation, exhibiting its potential use in research for the treatment of disuse osteoporosis (OP). Mar 26 2025
E8275 Z57346765 hydrochloride Z57346765 hydrochloride is an inhibitor of phosphoglycerate kinase 1 (PGK1) that binds to the ADP-binding pocket with a KD value of 2.09 × 10⁻⁵ M, reducing PGK1 metabolic enzyme activity, glucose consumption, and lactate production. It also inhibits DNA replication, impairs DNA damage repair, and induces cell cycle arrest in kidney renal clear cell carcinoma (KIRC) cells. Mar 26 2025
E8276 Golidocitinib 1-hydroxy-2-naphthoate Golidocitinib 1-hydroxy-2-naphthoate is a derivative of Golidocitinib, an oral, potent, selective inhibitor of Janus kinase 1 (JAK1) with an IC50 of 70 nM. It exhibits enhnaced antitumor activity and can be used for the treatment of cancer, including peripheral T cell lymphoma (PTCL). Mar 26 2025
E5871 VAV1 degrader-3 VAV1 degrader-3 (MRT-6160) is an orally active molecular glue degrader of VAV1 with a DC50 of 7 nM. It suppresses immune activation, proliferation, and cytokine production, inhibiting disease progression in inflammatory and autoimmune models like encephalomyelitis (EAE) and Collagen-induced arthritis (CIA). Mar 26 2025