All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E7361 (±)-Huperzine A (±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). Dec 19 2024
E7139 Gastric mucin Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. Dec 19 2024
E7362 Virginiamycin M1 Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665). Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL. Dec 19 2024
E7140 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers. Dec 19 2024
E7363 Canthaxanthin Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties. Dec 19 2024
E7364 2'-Deoxy-2'-fluorocytidine 2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication. Dec 19 2024
E7142 CGP-42112 CGP-42112 (CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist. Dec 19 2024
E7365 3-Epiursolic Acid 3-Epiursolic Acid is a triterpenoid that can be isolated from Eriobotrya japonica, acts as a competitive inhibitor of cathepsin L (IC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B. Dec 19 2024
E6008 Miglustat hydrochloride Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an effective, reversible, and non-toxic iminosugar and an inhibitor of ceramide-specific glucosyl transferase and β-glucosidase 2, with an IC50 of 32 μM and 81 μM, respectively. It is used in the treatment and research of dyslipidosis-related disorders, including GM1 gangliosidosis, Gaucher type I, Tay-Sachs disease, and Niemann-Pick type C disease (NPCD). Dec 19 2024
E1666 TPPB TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11.9 nM. Dec 19 2024
E7143 DTE DTE (Dithioerythritol) is a sulfur-containing sugar derived from the corresponding 4-carbon monosaccharide erythrose; an epimer of dithiothreitol (DTT). Dec 19 2024
E7366 Veliparib dihydrochloride Veliparib (dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Kis of 5.2 nM and 2.9 nM in cell-free assays, respectively. Dec 19 2024
E7144 PAR-4 Agonist Peptide, amide PAR-4 Agonist Peptide, amide (PAR-4-AP, AY-NH2) is a agonist of proteinase-activated receptor-4 (PAR-4) that provides antinociceptive effects in stress- and inflammation-induced hyperalgesia. It reduces visceral pain by activating PAR-4 receptors on colonic nerve terminals. Dec 19 2024
E7367 Beaucage reagent Beaucage reagent is found to be potent in causing DNA cleavage. Dec 19 2024
E7368 Light green SF yellowish Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains. Dec 19 2024
E7146 VIP(6-28)(human, rat, porcine, bovine) VIP(6-28)(human, rat, porcine, bovine) is an effective antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) on cAMP. Dec 19 2024
E7369 Zaprinast Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5). Zaprinast causes a significant increase in cGMP levels in myocytes. Zaprinast is a G protein-coupled receptor 35 (GPR35) agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects. Dec 19 2024
E1518 DPQ DPQ is a potent inhibitor of Poly (ADP-ribose) polymerase (PARP), with an IC50 of 40 nM for PARP1. It also suppresses macrophage-mediated inflammation and mitigates acute lung injury (ALI) induced by lipopolysaccharide (LPS) challenge in mice. Dec 19 2024
E7370 Chromium(III) acetate Chromium(III) acetate (Chromic acetate) is an AMPK inhibitor that promotes lipogenesis by inhibiting AMPK phosphorylation. Chromium(III) acetate has low toxicity in mammals, with an LD50 of 2365 mg/kg in rats. Dec 19 2024
E7147 Senktide Senktide is a tachykinin NK3 receptor agonist. Dec 19 2024